Endogenous catecholamine synthesis, metabolism, storage, and uptake in human peripheral blood mononuclear cells

Experimental Hematology

Volumn 27, Issue 3, 1999, Pages 489-495

  Marino, Franca ^a   Cosentino, Marco ^a   Bombelli, Raffaella ^a   Ferrari, Marco ^a   Lecchini, Sergio ^a   Frigo, Gianmario ^a  

^a 2nd Faculty of Medicine   (Italy)

Author keywords

Catecholamine metabolism; Catecholamines; Peripheral blood mononuclear cells

Indexed keywords

ADRENALIN; DOPAMINE; NORADRENALIN;

ADRENALIN RELEASE; ADRENERGIC SYSTEM; ARTICLE; CATECHOLAMINE SYNTHESIS; CELL LEVEL; DOPAMINE METABOLISM; HUMAN; HUMAN CELL; IMMUNOREGULATION; MONONUCLEAR CELL; NORADRENALIN RELEASE; PRIORITY JOURNAL;

ADULT; ALPHA-METHYLTYROSINE; CALCIUM; CATECHOLAMINES; ENZYME INHIBITORS; HUMANS; INTRACELLULAR FLUID; LEUKOCYTES, MONONUCLEAR; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; NEUROIMMUNOMODULATION; PARGYLINE; TYROSINE 3-MONOOXYGENASE;

EID: 0033015543     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(98)00057-5     Document Type: Article

References (30)

1. Felten D.L. Direct innervation of lymphoid organs. substrate for neurotransmitter signaling of cells of the immune system Neuropsychobiology. 28:1993;110.
2. Friedman E.M., Irwin M.R. Modulation of immune cell function by the autonomic nervous system. Pharmacol Ther. 74:1997;27.
3. Yu B., Shinnick-Gallagher P. Interleukin-1 beta inhibits synaptic transmission and induces hyperpolarization in amigdala neurons. J Pharmacol Exp Ther. 271:1994;590.
4. Bognar I.T., Albrecht S.A., Farasaty M., Fuder H. Inhibition by interleukin-1 beta of noradrenaline release in rat spleen. involvement of lymphocytes, NO and opioid receptors Naunyn-Schmiedebergs Arch Pharmacol. 351:1995;433.
5. Josefsson E., Bergquist J., Ekman R., Tarkowski A. Catecholamines are synthesized by mouse lymphocytes and regulate function of these cells by induction of apoptosis. Immunology. 88:1996;140.
6. Bergquist J., Tarkowski A., Ekman R., Ewing A. Discovery of endogenous catecholamines in lymphocytes and evidence for catecholamine regulation of lymphocyte function via an autocrine loop. Proc Natl Acad Sci U S A. 91:1994;12912.
7. Bergquist J., Josefsson E., Tarkowski A., Ekman R., Ewing A. Measurements of catecholamine-mediated apoptosis of immunocompetent cells by capillary electrophoresis. Electrophoresis. 18:1997;1760.
8. Musso N.R., Brenci S.B., Setti M., Indiveri F., Lotti G. Catecholamine content and in vitro catecholamine synthesis in peripheral human lymphocytes. J Clin Endocrinol Metab. 81:1996;3553.
9. Faraj B.A., Olkowski Z.L., Jackson R.T. Binding of [3H]-dopamine to human lymphocytes. possible relationship to neurotransmitter uptake sites Pharmacology. 42:1991;135.
10. Chelmicka-Schorr E., Arnason B.G. Nervous system-immune system interactions and their role in multiple sclerosis. Ann Neurol. 36:1994;S29.
11. Kamp T., Liebl B., Haen E., Emmerich B., Hallek M. Defects of beta 2-adrenergic signal transduction in chronic lymphocytic leukaemia. relationship to disease progression Eur J Clin Invest. 27:1997;121.
12. Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest. 21(suppl. 97):1968;77.
13. Marino F., Cosentino M., Bombelli R., Ferrari M., Maestroni G.J.M., Conti A., Lecchini S., Frigo G.M. Measurement of catecholamines in mouse bone marrow by means of HPLC with electrochemical detection. Haematologica. 82:1997;392.
14. Wester P. Simultaneous liquid chromatographic determination of seventeen of the major monoamine neurotransmitters, precursors and metabolites. I. Optimization of the mobile phase using factorial designs and a computer program to predict chromatograms. J Chromatogr Biomed Appl. 415:1987;261.
15. Masserano J.M., Vulliet P.R., Tank A.V., Weiner N. The role of tyrosine hydroxylase in the regulation of the catecholamine synthesis. Trendelenburg U., Weiner N. Catecholamines II. 1989;Springer, Heidelberg. 427p.
16. Youdim MBH, Finberg JPM, Tipton KF (1989) Monoamine oxidase. In: Trendelenburg U, Weiner N (eds.) Catecholamines I. Heidelberg, Springer, p. 119.
17. Shore P.A. The mechanism of noephinephrine depletion by reserpine, metaraminol and related agents. The role of monoamine oxidase. Pharmacol Rev. 18:1966;561.
18. Knudsen J.H., Christensen N.J., Bratholm P. Peripheral catecholaminergic function evaluated by norepinephrine measurements in plasma, extracellular fluid, and lymphocytes, from nerve recordings and cellular responses. Life Sci. 59:1996;639.
19. Williams L.T., Snyderman R., Lefkowitz R.J. Identification of beta-adrenergic receptors in human lymphocytes by (-)(3H) alprenolol binding. J Clin Invest. 57:1976;149.
20. Santambrogio L., Lipartiti M., Bruni A., Dal Torso R. Dopamine receptors on human T- and B-lymphocytes. J Neroimmunol. 45:1993;113.
21. Kirshner N. Uptake of catecholamines by a particulate fraction of the adrenal medulla. J Biol Chem. 327:1962;2311.
22. 2+-ATP dependent storage mechanisms in the amine granules of the adrenal medulla. Acta Physiol Scand. 59(suppl. 2151):1963.
23. Faraj B.A., Olkowski Z.L., Jackson R.T. Active [3H]-dopamine uptake by human lymphocytes. correlates with serotonin transporter activity Pharmacology. 48:1994;320.
24. Slominski A., Goodman-Snitkoff G. Dopa inhibits induced proliferative activity of murine and human lymphocytes. Anticancer Res. 12:1992;753.
25. Hadden J.W., Hadden E.M., Middleton E. Lymphocyte blast transformation. I. Demonstration of adrenergic receptors in human peripheral lymphocytes. J Cell Immunol. 1:1970;583.
26. Hellstrand K., Hermodsson S., Strannegard O. Evidence for a beta-adrenoceptor-mediated regulation of human natural killer cells. J Immunol. 134:1985;4095.
27. Hu X.X., Goldmuntz E.A., Brosnan C.F. The effect of norepinephrine on endotoxin-mediated macrophage activation. J Neuroimmunol. 31:1991;35.
28. Maestroni G.J.M., Conti A., Pedrinis E. Effect of adrenergic agents on hematopoiesis after syngeneic bone marrow transplantation in mice. Blood. 80:1992;1178.
29. Maestroni G.J.M., Conti A. Modulation of hematopoiesis via alpha 1-adrenergic receptors on bone marrow cells. Exp Hematol. 22:1994;313.
30. Maestroni G.J.M., Conti A. Noradrenergic modulation of lymphohematopoiesis. Int J Immunopharmacol. 16:1994;117.