Neuropsychological course of voltage-gated potassium channel and glutamic acid decarboxylase antibody related limbic encephalitis

European Journal of Neurology

Volumn 20, Issue 9, 2013, Pages 1297-1304

  Frisch, C ^a   Malter, M P ^a   Elger, C E ^a   Helmstaedter, C ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Attention; Epilepsy; Limbic encephalitis subforms; Long term; Memory

Indexed keywords

GLUTAMATE DECARBOXYLASE ANTIBODY; METHYLPREDNISOLONE; VOLTAGE GATED POTASSIUM CHANNEL;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; EXECUTIVE FUNCTION; HUMAN; IMMUNOTHERAPY; LEARNING DISORDER; MENTAL PERFORMANCE; NEUROPSYCHOLOGICAL TEST; PARANEOPLASTIC NEUROPATHY; PRIORITY JOURNAL; SCHOOL CHILD; SEIZURE; TREATMENT RESPONSE; VERBAL MEMORY;

ATTENTION; EPILEPSY; LIMBIC ENCEPHALITIS SUBFORMS; LONG TERM; MEMORY;

ADOLESCENT; ADULT; AGED; AUTOANTIBODIES; AUTOANTIGENS; BRAIN; CHILD; FEMALE; GLUTAMATE DECARBOXYLASE; HUMANS; IMMUNOPRECIPITATION; LIMBIC ENCEPHALITIS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POTASSIUM CHANNELS, VOLTAGE-GATED; YOUNG ADULT;

EID: 84881027315     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/ene.12186     Document Type: Article

References (34)

1. Nabbout R. Autoimmune and inflammatory epilepsies. Epilepsia 2012; 53(Suppl. 4): 58-62.
2. Flanagan EP, Caselli RJ. Autoimmune encephalopathy. Semin Neurol 2011; 31: 144-157.
3. Malter MP, Helmstaedter C, Urbach H, Vincent A, Bien CG. Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis. Ann Neurol 2010; 67: 470-478.
4. Parthasarathi UD, Harrower T, Tempest M, et al. Psychiatric presentation of voltage-gated potassium channel antibody-associated encephalopathy. Case report. Br J Psychiatry 2006; 189: 182-183.
5. Kitten S, Gupta N, Bloch RM, Dunham CK. Voltage-gated potassium channel antibody associated mood disorder without paraneoplastic disease. Biol Psychiatry 2011; 70: e15-e17.
6. Geschwind MD, Tan KM, Lennon VA, et al. Voltage-gated potassium channel autoimmunity mimicking Creutzfeldt-Jakob disease. Arch Neurol 2008; 65: 1341-1346.
7. Chan D, Henley SM, Rossor MN, Warrington EK. Extensive and temporally ungraded retrograde amnesia in encephalitis associated with antibodies to voltage-gated potassium channels. Arch Neurol 2007; 64: 404-410.
8. Lalic T, Pettingill P, Vincent A, Capogna M. Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission. Epilepsia 2011; 52: 121-131.
9. Vincent A, Bien CG, Irani SR, Waters P. Autoantibodies associated with diseases of the CNS: new developments and future challenges. Lancet Neurol 2011; 10: 759-772.
10. Bien CG, Urbach H, Schramm J, et al. Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy. Neurology 2007; 69: 1236-1244.
11. Urbach H. Imaging of the epilepsies. Eur Radiol 2005; 15: 494-500.
12. Vincent A, Buckley C, Schott JM, et al. Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis. Brain 2004; 127: 701-712.
13. Lutz MT, Helmstaedter C. EpiTrack: tracking cognitive side effects of medication on attention and executive functions in patients with epilepsy. Epilepsy Behav 2005; 7: 708-714.
14. Helmstaedter C, Lendt M, Lux S, eds. VLMT: Verbaler Lern- und Merkfähigkeitstest. Testhandbuch. Göttingen: Hogrefe, 2000.
15. Helmstaedter C, Pohl C, Elger CE. Eine modifizierte Version des Diagnostikums für Cerebralschäden (DCS) zur Diagnostik räumlich-visueller Gedächtnisdefizite bei Patienten mit Temporallappenepilepsie. In: Scheffner D, ed. Epilepsie 90. Reinbek: Einhorn-Presse, 1991: 272-279.
16. Helmstaedter C, Grunwald T, Lehnertz K, Gleissner U, Elger CE. Differential involvement of left temporolateral and temporomesial structures in verbal declarative learning and memory: evidence from temporal lobe epilepsy. Brain Cogn 1997; 35: 110-131.
17. Flanagan EP, McKeon A, Lennon VA, et al. Autoimmune dementia: clinical course and predictors of immunotherapy response. Mayo Clin Proc 2010; 85: 881-897.
18. Rolls ET. An attractor network in the hippocampus: theory and neurophysiology. Learn Mem 2007; 14: 714-731.
19. Goodrich-Hunsaker NJ, Hopkins RO. Word memory test performance in amnesic patients with hippocampal damage. Neuropsychology 2009; 23: 529-534.
20. Rosenbaum RS, Moscovitch M, Foster JK, et al. Patterns of autobiographical memory loss in medial-temporal lobe amnesic patients. J Cogn Neurosci 2008; 20: 1490-1506.
21. Race E, Keane MM, Verfaellie M. Medial temporal lobe damage causes deficits in episodic memory and episodic future thinking not attributable to deficits in narrative construction. J Neurosci 2011; 31: 10262-10269.
22. Kartsounis LD, de Silva R. Unusual amnesia in a patient with VGKC-Ab limbic encephalitis: a case study. Cortex 2011; 47: 451-459.
23. Cossette M, Levesque D, Parent A. Neurochemical characterization of dopaminergic neurons in human striatum. Parkinsonism Relat Disord 2005; 11: 277-286.
24. Schreiber S, Bernstein HG, Fendrich R, et al. Increased density of GAD65/67 immunoreactive neurons in the posterior subiculum and parahippocampal gyrus in treated patients with chronic schizophrenia. World J Biol Psychiatry 2011; 12: 57-65.
25. Najjar S, Pearlman D, Najjar A, Ghiasian V, Zagzag D, Devinsky O. Extralimbic autoimmune encephalitis associated with glutamic acid decarboxylase antibodies: an underdiagnosed entity? Epilepsy Behav 2011; 21: 306-313.
26. Brunner R, Schaefer D, Hess K, Parzer P, Resch F, Schwab S. Effect of corticosteroids on short-term and long-term memory. Neurology 2005; 64: 335-337.
27. Badre D, Hoffman J, Cooney JW, D'Esposito M. Hierarchical cognitive control deficits following damage to the human frontal lobe. Nat Neurosci 2009; 12: 515-522.
28. Axmacher N, Henseler MM, Jensen O, Weinreich I, Elger CE, Fell J. Cross-frequency coupling supports multi-item working memory in the human hippocampus. Proc Natl Acad Sci USA 2010; 107: 3228-3233.
29. Gordon JA. Oscillations and hippocampal-prefrontal synchrony. Curr Opin Neurobiol 2011; 21: 486-491.
30. Piekema C, Kessels RPC, Mars RB, Petersson KM, Fernández G. The right hippocampus participates in short-term memory maintenance of object-location associations. Neuroimage 2006; 33: 374-382.
31. Meulenbroek O, Kessels RP, de Rover M, et al. Age-effects on associative object-location memory. Brain Res 2010; 1315: 100-110.
32. Patel AB, de Graaf RA, Martin DL, Battaglioli G, Behar KL. Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo. J Neurochem 2006; 97: 385-396.
33. Walls AB, Nilsen LH, Eyjolfsson EM, et al. GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activity. J Neurochem 2010; 115: 1398-1408.
34. Bien CG, Vincent A, Barnett MH, et al. Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis. Brain 2012; 135: 1622-1638.