Extensive and temporally ungraded retrograde amnesia in encephalitis associated with antibodies to voltage-gated potassium channels

Archives of Neurology

Volumn 64, Issue 3, 2007, Pages 404-410

  Chan, Dennis ^a,b   Henley, Susie M D ^b   Rossor, Martin N ^b,c   Warrington, Elizabeth K ^b  

^a ROYAL SUSSEX COUNTY HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOSUPPRESSIVE AGENT; PREDNISONE; VOLTAGE GATED POTASSIUM CHANNEL;

ADULT; ARTICLE; BEHAVIOR CHANGE; CASE REPORT; CLINICAL FEATURE; DISEASE ASSOCIATION; DISEASE COURSE; ENCEPHALITIS; EPILEPSY; HIPPOCAMPUS; HUMAN; IMMUNOTHERAPY; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PREVALENCE; PRIORITY JOURNAL; RADIODIAGNOSIS; RETROGRADE AMNESIA; SIGNAL PROCESSING; TEMPORAL LOBE;

ADULT; AMNESIA, RETROGRADE; ANTIBODIES; ENCEPHALITIS; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 33947272963     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneur.64.3.404     Document Type: Article

References (17)

1. Buckley C, Oger J, Clover L, et al. Potassium channel antibodies in two patients with reversible limbic encephalitis. Ann Neurol. 2001;50:73-78.
2. Thieben MJ, Lennon VA, Boeve BF, Aksamit AJ, Keegan M, Vernino S. Potentially reversible autoimmune limbic encephalitis with neuronal potassium channel antibody. Neurology. 2004;62:1177-1182.
3. Vincent A, Buckley C, Schott JM, et al. Potassium channel antibody-associated encephalopathy: a potentially treatable immunotherapy- responsive form of limbic encephalitis. Brain. 2004;127:701-712.
4. Squire LR, Cohen NJ, Nadel L. The medial temporal region and memory consolidation: a new hypothesis. In: Weingartner H, Parker E, eds. Memory Consolidation. Hillsdale, Ill: Lawrence A Erlbaum Associates; 1984:185-210.
5. Teyler TJ, DiScenna P. The hippocampal memory indexing system. Behav Neurosci. 1986;100:147-154.
6. Warrington EK, Weiskrantz L. Amnesia: a disconnection syndrome? Neuropsychologia. 1982;20:233-248.
7. Nadel L, Moscovitch M. Memory consolidation, retrograde amnesia and the hippocampal complex. Curr Opin Neurobiol. 1997;7:217-227.
8. Schott JM, Harkness K, Barnes J, della Rocchetta AI, Vincent A, Rossor MN. Amnesia, cerebral atrophy, and autoimmunity [letter] [published correction appears in Lancet. 2004;363:86]. Lancet. 2003;361:1266.
9. Hartley T, Bird CM, Chan D, et al. The hippocampus is required for short-term topographical memory in humans. Hippocampus. In press.
10. Warrington EK. Recognition Memory Test. Windsor, England: NFER-Nelson; 1984.
11. Weschler D. Manual for the Wechsler Adult Intelligence Scale-Revised. New York: New York Psychological Corp; 1981.
12. Urbach H, Soeder BM, Jeub M, Klockgether T, Meyer B, Bien CG. Serial MRI of limbic encephalitis. Neuroradiology. 2006;48:380-386.
13. + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature. 1997;387:869-875.
14. Dorandeu F, Wetherall J, Pernot-Marino I, Tattersall JEH, Fosbracy P. Effects of excitatory amino acid antagonists on dendrotoxin-induced increases in neurotransmitter release and epileptiform bursting in rat hippocampus in vitro. J Neurosci Res. 1997;48:499-506.
15. Golding NL, Jung H, Mickus T, Spruston N. Dendritic calcium spike initiation and repolarization are controlled by distinct potassium channel subtypes in CA1 pyramidal neurons. J Neurosci. 1999;19:8789-8798.
16. Smart SL, Lopantsev V, Zhang CL, et al. Deletion of the K1.1 potassium channel causes epilepsy in mice. Neuron. 1998;20:809-819.
17. Gratacos E, Ghelardini C, Gherardini LM, et al. Kv1.1 channel antisense attenuates learning and modulation of dentate polysialylated NCAM. Neuroreport. 1998;9:2727-2731.