Metal ions activate vascular endothelial cells and increase lymphocyte chemotaxis and binding

Journal of Orthopaedic Research

Volumn 31, Issue 9, 2013, Pages 1484-1491

  Ninomiya, James T ^a   Kuzma, Scott A ^a   Schnettler, Timothy J ^a   Krolikowski, John G ^a   Struve, Janine A ^a   Weihrauch, Dorothee ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

endothelium; lymphocytes; metal on metal

Indexed keywords

CHROMIUM; COBALT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; METAL ION; MONOCYTE CHEMOTACTIC PROTEIN 1;

ARTICLE; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOCYTE MIGRATION; PRIORITY JOURNAL; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; VASCULITIS;

ENDOTHELIUM; LYMPHOCYTES; METAL ON METAL;

BLOTTING, WESTERN; CELL ADHESION; CELL SURVIVAL; CHEMOKINE CCL2; CHEMOTAXIS, LEUKOCYTE; CHLORIDES; CHROMIUM COMPOUNDS; COBALT; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-8; IONS; JURKAT CELLS; LYMPHOCYTES; METAL-ON-METAL JOINT PROSTHESES; UP-REGULATION;

EID: 84881022485     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22377     Document Type: Article

References (37)

1. Cuckler JM., 2005. The rationale for metal-on-metal total hip arthroplasty. Clin Orthop Relat Res 441: 132-136.
2. Antoniou J, Zukor DJ, Mwale F, et al. 2008. Metal ion levels in the blood of patients after hip resurfacing: a comparison between twenty-eight and thirty-six-millimeter-head metal-on-metal prostheses. J Bone Joint Surg Am 3: 142-148.
3. Cobb AG, Schmalzreid TP., 2006. The clinical significance of metal ion release from cobalt-chromium metal-on-metal hip joint arthroplasty. Proc Inst Mech Eng [H] 220: 385-398.
4. Dunstan E, Sanghrajka AP, Tilley S, et al. 2005. Metal ion levels after metal-on-metal proximal femoral replacements: a 30-year follow-up. J Bone Joint Surg Br 87: 628-631.
5. Dunstan E, Ladon D, Whittingham-Jones P, et al. 2008. Chromosomal aberrations in the peripheral blood of patients with metal-on-metal hip bearings. J Bone Joint Surg Am 90: 517-522.
6. Jacobs JJ, Urban RM, Hallab NJ, et al. 2009. Metal-on-metal bearing surfaces. J Am Acad Orthop Surg 17: 69-76.
7. Urban RM, Tomlinson MJ, Hall DJ, et al. 2004. Accumulation in liver and spleen of metal particles generated at nonbearing surfaces in hip arthroplasty. J Arthroplasty 19: 94-101.
8. Willert HG, Buchhorn GH, Fayyazi A, et al. 2005. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints. A clinical and histomorphological study. J Bone Joint Surg Am 87: 28-36.
9. Cook-Mills JM, Deem TL., 2005. Active participation of endothelial cells in inflammation. J Leukoc Biol 77: 487-495.
10. Hallab NJ, Caicedo M, Finnegan A, et al. 2008. Th1 type lymphocyte reactivity to metals in patients with total hip arthroplasty. J Orthop Surg Res 3: 6.
11. Jensen P, Thyssen JP, Retpen JB, et al. 2009. Cobalt allergy and suspected aseptic lymphocyte-dominated vascular-associated lesion following total hip arthroplasty. Contact Dermatitis 61: 238-239.
12. Sultana C, Shen Y, Johnson C, et al. 1999. Cobalt chloride-induced signaling in endothelium leading to the augmented adherence of sickle red blood cells and transendothelial migration of monocyte-like HL-60 cells is blocked by PAF-receptor antagonist. J Cell Physiol 179: 67-78.
13. Thomas P, Braathen LR, Dorig M, et al. 2009. Increased metal allergy in patients with failed metal-on-metal hip arthroplasty and peri-implant T-lymphocytic inflammation. Allergy 64: 1157-1165.
14. Kwon YM, Thomas P, Summer B, et al. 2010. Lymphocyte proliferation responses in patients with pseudotumors following metal-on-metal hip resurfacing arthroplasty. J Orthop Res 28: 444-450.
15. Cai JP, Hudson S, Ye MW, et al. 1996. The intracellular signaling pathways involved in MCP-1-stimulated T cell migration across microvascular endothelium. Cell Immunol 167: 269-275.
16. Santamaria Babi LF, Moser B, Perez Soler MT, et al. 1996. The interleukin-8 receptor B and CXC chemokines can mediate transendothelial migration of human skin homing T cells. Eur J Immunol 26: 2056-2061.
17. Hallab NJ, Jacobs JJ., 2009. Biologic effects of implant debris. Bull NYU Hosp Joint Dis 67: 182.
18. Caicedo M, Jacobs JJ, Reddy A, et al. 2008. Analysis of metal ion-induced DNA damage, apoptosis, and necrosis in human (jurkat) T-cells demonstrates Ni2+ and V3+ are more toxic than other metals: Al3+, Be2+, Co2+, Cr3+, Cu2+, Fe3+, Mo5+, Nb5+, Zr2+. J Biomed Mater Res A 86: 905-913.
19. Busse B, Hahn M, Niecke M, et al. Allocation of nonbirefringent wear debris: darkfield illumination associated with PIXE microanalysis reveals cobalt deposition in mineralized bone matrix adjacent to CoCr implants.
20. Wagner M, Klein CL, van Kooten TG, et al. 1998. Mechanisms of cell activation by heavy metal ions. J Biomed Mater Res 42: 443-452.
21. Davies AP, Willert HG, Campbell PA, et al. 2005. An unusual lymphocytic perivascular infiltration in tissues around contemporary metal-on-metal joint replacements. J Bone Joint Surg Am 87: 18-27.
22. Pandit H, Vlychou M, Whitwell D, et al. 2008. Necrotic granulomatous pseudotumours in bilateral resurfacing hip arthoplasties: evidence for a type IV immune response. Virchows Arch 453: 529-534.
23. Campbell P, Ebramzadeh E, Nelson S, et al. 2010. Histological features of pseudotumor-like tissues from metal-on-metal hips. Clin Orthop Relat Res 468: 2321-2327.
24. Kraft CN, Burian B, Diedrich O, et al. 2005. Microvascular response of striated muscle to common arthroplasty-alloys: a comparative in vivo study with CoCrMo, ti-6Al-4V, and ti-6Al-7Nb. J Biomed Mater Res A 75: 31-40.
25. Kraft CN, Diedrich O, Burian B, et al. 2003. Microvascular response of striated muscle to metal debris. A comparative in vivo study with titanium and stainless steel. J Bone Joint Surg Br 85: 133-141.
26. Utzschneider S, Becker F, Grupp TM, et al. 2010. Inflammatory response against different carbon fiber-reinforced PEEK wear particles compared with UHMWPE in vivo. Acta Biomater 6: 4296-4304.
27. Zysk SP, Gebhard HH, Kalteis T, et al. 2005. Particles of all sizes provoke inflammatory responses in vivo. Clin Orthop Relat Res 258-264.
28. Rahman A, Fazal F., 2009. Hug tightly and say goodbye: role of endothelial ICAM-1 in leukocyte transmigration. Antioxid Redox Signal 11: 823-839.
29. Delaunay C, Petit I, Learmonth ID, et al. 2010. Metal-on-metal bearings total hip arthroplasty: the cobalt and chromium ions release concern. Orthop Traumatol, Surg Res 96: 894-904.
30. Liu S, Wu P, Ye D, et al. 2009. Effects of lipoxin A(4) on CoCl(2)-induced angiogenesis and its possible mechanisms in human umbilical vein endothelial cells. Pharmacology 84: 17-23.
31. Korovessis P, Petsinis G, Repanti M, et al. 2006. Metallosis after contemporary metal-on-metal total hip arthroplasty. five to nine-year follow-up. J Bone Joint Surg Am 88: 1183-1191.
32. MacDonald SJ., 2004. Can a safe level for metal ions in patients with metal-on-metal total hip arthroplasties be determined ? J Arthroplasty 19: 71-77.
33. Templeton D., 2004. Mechanisms of Immunosensitization to metals. Pure Appl Chem 76: 1255-1268.
34. Caicedo MS, Pennekamp PH, McAllister K, et al. 2010. Soluble ions more than particulate cobalt-alloy implant debris induce monocyte costimulatory molecule expression and release of proinflammatory cytokines critical to metal-induced lymphocyte reactivity. J Biomed Mater Res A 93: 1312-1321.
35. Fujishiro T, Moojen DJF, Kobayashi N, et al. 2011. Perivascular and diffuse lymphocytic inflammation are not specific for failed metal-on-metal hip implants. Clin Orthop Relat Res 469: 1127-1133.
36. Hallab NJ, Anderson S, Stafford T, et al. 2005. Lymphocyte responses in patients with total hip arthroplasty. J Orthop Res 23: 384-391.
37. Hallab NJ, Mikecz K, Vermes C, et al. 2001. Differential lymphocyte reactivity to serum-derived metal-protein complexes produced from cobalt-based and titanium-based implant alloy degradation. J Biomed Mater Res 56: 427-436.