메뉴 건너뛰기




Volumn 8, Issue 8, 2013, Pages 873-884

E2f6-mediated repression of the meiotic Stag3 and Smc1β genes during early embryonic development requires Ezh2 and not the de novo methyltransferase Dnmt3b

Author keywords

DNA methylation; E2f6; Embryonic development; Ezh2; Germline genes; Stem cells; Transcriptional silencing

Indexed keywords

ALPHA TUBULIN; COLLAGEN TYPE 11; DNA METHYLTRANSFERASE 3B; FIBROBLAST GROWTH FACTOR 5; KRUPPEL LIKE FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN; SLC25A31 PROTEIN; SMC1 BETA PROTEIN; STAG3 PROTEIN; TRANSCRIPTION FACTOR E2F6; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 84881018011     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.25522     Document Type: Article
Times cited : (13)

References (29)
  • 1
    • 84868591105 scopus 로고    scopus 로고
    • Intercellular interactions, position, and polarity in establishing blastocyst cell lineages and embryonic axes
    • PMID:23125013
    • Stephenson RO, Rossant J, Tam PP. Intercellular interactions, position, and polarity in establishing blastocyst cell lineages and embryonic axes. Cold Spring Harb Perspect Biol 2012; 4:4; PMID:23125013; http:// dx.doi.org/10.1101/cshperspect.a008235
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , pp. 4
    • Stephenson, R.O.1    Rossant, J.2    Tam, P.P.3
  • 3
    • 0032490832 scopus 로고    scopus 로고
    • E2F-6: A novel member of the E2F family is an inhibitor of E2F-dependent transcription
    • PMID:9704927
    • Cartwright P, Müller H, Wagener C, Holm K, Helin K. E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 1998; 17:611-23; PMID:9704927; http://dx.doi. org/10.1038/sj.onc.1201975
    • (1998) Oncogene , vol.17 , pp. 611-623
    • Cartwright, P.1    Müller, H.2    Wagener, C.3    Holm, K.4    Helin, K.5
  • 4
    • 0035914059 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the mouse E2F6 gene
    • PMID:11594747
    • Kherrouche Z, Begue A, Stehelin D, Monté D. Molecular cloning and characterization of the mouse E2F6 gene. Biochem Biophys Res Commun 2001; 288:22-33; PMID:11594747; http://dx.doi. org/10.1006/bbrc.2001.5718
    • (2001) Biochem Biophys Res Commun , vol.288 , pp. 22-33
    • Kherrouche, Z.1    Begue, A.2    Stehelin, D.3    Monté, D.4
  • 5
    • 20144379783 scopus 로고    scopus 로고
    • A role for E2F6 in the restriction of male-germ-cell-specific gene expression
    • PMID:15936277
    • Pohlers M, Truss M, Frede U, Scholz A, Strehle M, Kuban RJ, et al. A role for E2F6 in the restriction of male-germ-cell-specific gene expression. Curr Biol 2005; 15:1051-7; PMID:15936277; http://dx.doi. org/10.1016/j.cub.2005.04.060
    • (2005) Curr Biol , vol.15 , pp. 1051-1057
    • Pohlers, M.1    Truss, M.2    Frede, U.3    Scholz, A.4    Strehle, M.5    Kuban, R.J.6
  • 6
    • 29244470501 scopus 로고    scopus 로고
    • Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6
    • PMID:16236716
    • Storre J, Schäfer A, Reichert N, Barbero JL, Hauser S, Eilers M, et al. Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6. J Biol Chem 2005; 280:41380-6; PMID:16236716; http:// dx.doi.org/10.1074/jbc.M506797200
    • (2005) J Biol Chem , vol.280 , pp. 41380-41386
    • Storre, J.1    Schäfer, A.2    Reichert, N.3    Barbero, J.L.4    Hauser, S.5    Eilers, M.6
  • 7
    • 55549103686 scopus 로고    scopus 로고
    • A conserved E2F6-binding element in murine meiosis-specific gene promoters
    • PMID:18667754
    • Kehoe SM, Oka M, Hankowski KE, Reichert N, Garcia S, McCarrey JR, et al. A conserved E2F6-binding element in murine meiosis-specific gene promoters. Biol Reprod 2008; 79:921-30; PMID:18667754; http:// dx.doi.org/10.1095/biolreprod.108.067645
    • (2008) Biol Reprod , vol.79 , pp. 921-930
    • Kehoe, S.M.1    Oka, M.2    Hankowski, K.E.3    Reichert, N.4    Garcia, S.5    McCarrey, J.R.6
  • 8
    • 0036023975 scopus 로고    scopus 로고
    • Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6
    • PMID:12101104
    • Storre J, Elsässer HP, Fuchs M, Ullmann D, Livingston DM, Gaubatz S. Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6. EMBO Rep 2002; 3:695-700; PMID:12101104; http://dx.doi.org/10.1093/embo-reports/kvf141
    • (2002) EMBO Rep , vol.3 , pp. 695-700
    • Storre, J.1    Elsässer, H.P.2    Fuchs, M.3    Ullmann, D.4    Livingston, D.M.5    Gaubatz, S.6
  • 9
    • 43449130065 scopus 로고    scopus 로고
    • E2f6 and Bmi1 cooperate in axial skeletal development
    • PMID:18366140
    • Courel M, Friesenhahn L, Lees JA. E2f6 and Bmi1 cooperate in axial skeletal development. Dev Dyn 2008; 237:1232-42; PMID:18366140; http://dx.doi. org/10.1002/dvdy.21516
    • (2008) Dev Dyn , vol.237 , pp. 1232-1242
    • Courel, M.1    Friesenhahn, L.2    Lees, J.A.3
  • 10
    • 0035852632 scopus 로고    scopus 로고
    • The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
    • PMID:11171983
    • Trimarchi JM, Fairchild B, Wen J, Lees JA. The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc Natl Acad Sci U S A 2001; 98:1519-24; PMID:11171983; http:// dx.doi.org/10.1073/pnas.98.4.1519
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1519-1524
    • Trimarchi, J.M.1    Fairchild, B.2    Wen, J.3    Lees, J.A.4
  • 11
    • 19944431321 scopus 로고    scopus 로고
    • A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner
    • PMID:15536069
    • Attwooll C, Oddi S, Cartwright P, Prosperini E, Agger K, Steensgaard P, et al. A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner. J Biol Chem 2005; 280:1199-208; PMID:15536069; http://dx.doi.org/10.1074/jbc.M412509200
    • (2005) J Biol Chem , vol.280 , pp. 1199-1208
    • Attwooll, C.1    Oddi, S.2    Cartwright, P.3    Prosperini, E.4    Agger, K.5    Steensgaard, P.6
  • 12
    • 0037052539 scopus 로고    scopus 로고
    • A complex with chromatin modifiers that occupies E2F-and Myc-responsive genes in G0 cells
    • PMID:12004135
    • Ogawa H, Ishiguro K, Gaubatz S, Livingston DM, Nakatani Y. A complex with chromatin modifiers that occupies E2F-and Myc-responsive genes in G0 cells. Science 2002; 296:1132-6; PMID:12004135; http:// dx.doi.org/10.1126/science.1069861
    • (2002) Science , vol.296 , pp. 1132-1136
    • Ogawa, H.1    Ishiguro, K.2    Gaubatz, S.3    Livingston, D.M.4    Nakatani, Y.5
  • 13
    • 79955972412 scopus 로고    scopus 로고
    • L3MBTL2 protein acts in concert with PcG proteinmediated monoubiquitination of H2A to establish a repressive chromatin structure
    • PMID:21596310
    • Trojer P, Cao AR, Gao Z, Li Y, Zhang J, Xu X, et al. L3MBTL2 protein acts in concert with PcG proteinmediated monoubiquitination of H2A to establish a repressive chromatin structure. Mol Cell 2011; 42:438-50; PMID:21596310; http://dx.doi.org/10.1016/j. molcel.2011.04.004
    • (2011) Mol Cell , vol.42 , pp. 438-450
    • Trojer, P.1    Cao, A.R.2    Gao, Z.3    Li, Y.4    Zhang, J.5    Xu, X.6
  • 14
    • 84866139087 scopus 로고    scopus 로고
    • The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development
    • PMID:22770845
    • Qin J, Whyte WA, Anderssen E, Apostolou E, Chen HH, Akbarian S, et al. The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development. Cell Stem Cell 2012; 11:319-32; PMID:22770845; http://dx.doi.org/10.1016/j. stem.2012.06.002
    • (2012) Cell Stem Cell , vol.11 , pp. 319-332
    • Qin, J.1    Whyte, W.A.2    Anderssen, E.3    Apostolou, E.4    Chen, H.H.5    Akbarian, S.6
  • 15
    • 77952695371 scopus 로고    scopus 로고
    • Dnmt3b recruitment through E2F6 transcriptional repressor mediates germline gene silencing in murine somatic tissues
    • PMID:20439742
    • Velasco G, Hubé F, Rollin J, Neuillet D, Philippe C, Bouzinba-Segard H, et al. Dnmt3b recruitment through E2F6 transcriptional repressor mediates germline gene silencing in murine somatic tissues. Proc Natl Acad Sci U S A 2010; 107:9281-6; PMID:20439742; http://dx.doi.org/10.1073/pnas.1000473107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 9281-9286
    • Velasco, G.1    Hubé, F.2    Rollin, J.3    Neuillet, D.4    Philippe, C.5    Bouzinba-Segard, H.6
  • 16
    • 84865843074 scopus 로고    scopus 로고
    • Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline
    • PMID:22949617
    • Hackett JA, Reddington JP, Nestor CE, Dunican DS, Branco MR, Reichmann J, et al. Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline. Development 2012; 139:3623-32; PMID:22949617; http://dx.doi.org/10.1242/dev.081661
    • (2012) Development , vol.139 , pp. 3623-3632
    • Hackett, J.A.1    Reddington, J.P.2    Nestor, C.E.3    Dunican, D.S.4    Branco, M.R.5    Reichmann, J.6
  • 17
    • 0037133565 scopus 로고    scopus 로고
    • Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    • PMID:11891299
    • Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A 2002; 99:3740-5; PMID:11891299; http://dx.doi.org/10.1073/pnas.052410099
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3740-3745
    • Takai, D.1    Jones, P.A.2
  • 18
    • 33744552284 scopus 로고    scopus 로고
    • CpG sites preferentially methylated by Dnmt3a in vivo
    • PMID:16439359
    • Oka M, Rodic N, Graddy J, Chang LJ, Terada N. CpG sites preferentially methylated by Dnmt3a in vivo. J Biol Chem 2006; 281:9901-8; PMID:16439359; http://dx.doi.org/10.1074/jbc.M511100200
    • (2006) J Biol Chem , vol.281 , pp. 9901-9908
    • Oka, M.1    Rodic, N.2    Graddy, J.3    Chang, L.J.4    Terada, N.5
  • 19
    • 27144447720 scopus 로고    scopus 로고
    • DNA methylation is required for silencing of ant4, an adenine nucleotide translocase selectively expressed in mouse embryonic stem cells and germ cells
    • PMID:16051982
    • Rodic N, Oka M, Hamazaki T, Murawski MR, Jorgensen M, Maatouk DM, et al. DNA methylation is required for silencing of ant4, an adenine nucleotide translocase selectively expressed in mouse embryonic stem cells and germ cells. Stem Cells 2005; 23:1314-23; PMID:16051982; http://dx.doi.org/10.1634/ stemcells.2005-0119
    • (2005) Stem Cells , vol.23 , pp. 1314-1323
    • Rodic, N.1    Oka, M.2    Hamazaki, T.3    Murawski, M.R.4    Jorgensen, M.5    Maatouk, D.M.6
  • 20
    • 18844397298 scopus 로고    scopus 로고
    • De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine
    • PMID:15735669
    • Oka M, Meacham AM, Hamazaki T, Rodic N, Chang LJ, Terada N. De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine. Oncogene 2005; 24:3091-9; PMID:15735669; http://dx.doi. org/10.1038/sj.onc.1208540
    • (2005) Oncogene , vol.24 , pp. 3091-3099
    • Oka, M.1    Meacham, A.M.2    Hamazaki, T.3    Rodic, N.4    Chang, L.J.5    Terada, N.6
  • 21
    • 79955616730 scopus 로고    scopus 로고
    • Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells
    • PMID:21490431
    • Villasante A, Piazzolla D, Li H, Gomez-Lopez G, Djabali M, Serrano M. Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells. Cell Cycle 2011; 10:1488-98; PMID:21490431; http://dx.doi. org/10.4161/cc.10.9.15658
    • (2011) Cell Cycle , vol.10 , pp. 1488-1498
    • Villasante, A.1    Piazzolla, D.2    Li, H.3    Gomez-Lopez, G.4    Djabali, M.5    Serrano, M.6
  • 22
    • 0037320925 scopus 로고    scopus 로고
    • Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement
    • PMID:12496962
    • Su IH, Basavaraj A, Krutchinsky AN, Hobert O, Ullrich A, Chait BT, et al. Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat Immunol 2003; 4:124-31; PMID:12496962; http://dx.doi.org/10.1038/ni876
    • (2003) Nat Immunol , vol.4 , pp. 124-131
    • Su, I.H.1    Basavaraj, A.2    Krutchinsky, A.N.3    Hobert, O.4    Ullrich, A.5    Chait, B.T.6
  • 23
    • 78649459828 scopus 로고    scopus 로고
    • Targets and dynamics of promoter DNA methylation during early mouse development
    • PMID:21057502
    • Borgel J, Guibert S, Li Y, Chiba H, Schübeler D, Sasaki H, et al. Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet 2010; 42:1093-100; PMID:21057502; http:// dx.doi.org/10.1038/ng.708
    • (2010) Nat Genet , vol.42 , pp. 1093-1100
    • Borgel, J.1    Guibert, S.2    Li, Y.3    Chiba, H.4    Schübeler, D.5    Sasaki, H.6
  • 24
    • 4744372577 scopus 로고    scopus 로고
    • Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
    • PMID:15456861
    • Jackson M, Krassowska A, Gilbert N, Chevassut T, Forrester L, Ansell J, et al. Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol Cell Biol 2004; 24:8862-71; PMID:15456861; http://dx.doi. org/10.1128/MCB.24.20.8862-8871.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 8862-8871
    • Jackson, M.1    Krassowska, A.2    Gilbert, N.3    Chevassut, T.4    Forrester, L.5    Ansell, J.6
  • 25
    • 32844459336 scopus 로고    scopus 로고
    • The Polycomb group protein EZH2 directly controls DNA methylation
    • PMID:16357870
    • Viré E, Brenner C, Deplus R, Blanchon L, Fraga M, Didelot C, et al. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 2006; 439:871-4; PMID:16357870; http://dx.doi. org/10.1038/nature04431
    • (2006) Nature , vol.439 , pp. 871-874
    • Viré, E.1    Brenner, C.2    Deplus, R.3    Blanchon, L.4    Fraga, M.5    Didelot, C.6
  • 26
    • 73449144780 scopus 로고    scopus 로고
    • Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation
    • PMID:19717977
    • Rush M, Appanah R, Lee S, Lam LL, Goyal P, Lorincz MC. Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation. Epigenetics 2009; 4:404-14; PMID:19717977; http://dx.doi.org/10.4161/ epi.4.6.9392
    • (2009) Epigenetics , vol.4 , pp. 404-414
    • Rush, M.1    Appanah, R.2    Lee, S.3    Lam, L.L.4    Goyal, P.5    Lorincz, M.C.6
  • 27
    • 55549103314 scopus 로고    scopus 로고
    • A model for transmission of the H3K27me3 epigenetic mark
    • PMID:18931660
    • Hansen KH, Bracken AP, Pasini D, Dietrich N, Gehani SS, Monrad A, et al. A model for transmission of the H3K27me3 epigenetic mark. Nat Cell Biol 2008; 10:1291-300; PMID:18931660; http://dx.doi. org/10.1038/ncb1787
    • (2008) Nat Cell Biol , vol.10 , pp. 1291-1300
    • Hansen, K.H.1    Bracken, A.P.2    Pasini, D.3    Dietrich, N.4    Gehani, S.S.5    Monrad, A.6
  • 28
    • 36749083455 scopus 로고    scopus 로고
    • A new class of tissue-specifically methylated regions involving entire CpG islands in the mouse
    • PMID:18076568
    • Suzuki M, Sato S, Arai Y, Shinohara T, Tanaka S, Greally JM, et al. A new class of tissue-specifically methylated regions involving entire CpG islands in the mouse. Genes Cells 2007; 12:1305-14; PMID:18076568; http://dx.doi.org/10.1111/j.1365-2443.2007.01136.x
    • (2007) Genes Cells , vol.12 , pp. 1305-1314
    • Suzuki, M.1    Sato, S.2    Arai, Y.3    Shinohara, T.4    Tanaka, S.5    Greally, J.M.6
  • 29
    • 0036856355 scopus 로고    scopus 로고
    • MethPrimer: Designing primers for methylation PCRs
    • PMID:12424112
    • Li LC, Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics 2002; 18:1427-31; PMID:12424112; http://dx.doi.org/10.1093/bioinformatics/ 18.11.1427
    • (2002) Bioinformatics , vol.18 , pp. 1427-1431
    • Li, L.C.1    Dahiya, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.