Levels of Murine, but Not Human, CXCL13 Are Greatly Elevated in NOD-SCID Mice Bearing the AIDS-Associated Burkitt Lymphoma Cell Line, 2F7

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Widney, Daniel P ^a   Olafsen, Tove ^a,c   Wu, Anna M ^a,c   Kitchen, Christina M R ^b   Said, Jonathan W ^a   Smith, Jeffrey B ^a   Peña, Guadalupe ^a   Magpantay, Larry I ^a   Penichet, Manuel L ^a   Martinez Maza, Otoniel ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; CXCL13 CHEMOKINE; TUMOR MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BURKITT LYMPHOMA; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INNATE IMMUNITY; LYMPHOMA CELL; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR XENOGRAFT;

ANIMALS; ASCITES; BURKITT LYMPHOMA; CHEMOKINE CXCL13; FEMALE; FLOW CYTOMETRY; HIV-1; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHOMA, AIDS-RELATED; MICE; MICE, INBRED NOD; MICE, SCID; TUMOR CELLS, CULTURED;

EID: 84881014701     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072414     Document Type: Article

References (35)

1. Carbone A, Gloghini A, Capello D, Gaidano G, (2001) Genetic pathways and histogenetic models of AIDS-related lymphomas. Eur J Cancer 37: 1270-1275. doi:10.1016/S0959-8049(01)00119-8. PubMed: 11423258.
2. Grogg KL, Miller RF, Dogan A, (2007) HIV infection and lymphoma. J Clin Pathol 60: 1365-1372. PubMed: 18042692.
3. Martínez-Maza O, Breen EC, (2002) B-cell activation and lymphoma in patients with HIV. Curr Opin Oncol 14: 528-532. doi:10.1097/00001622-200209000-00009. PubMed: 12192272.
4. Brower V, (2010) Clues emerge on how HIV increases lymphoma risk. J Natl Cancer Inst 102: 1002-1004. doi:10.1093/jnci/djq274. PubMed: 20616350.
5. Huysentruyt LC, McGrath MS, (2010) The role of macrophages in the development and progression of AIDS-related non-Hodgkin lymphoma. J Leukoc Biol 87: 627-632. doi:10.1189/jlb.0809564. PubMed: 20042471.
6. Zenger E, Abbey NW, Weinstein MD, Kapp L, Reis J, et al. (2002) Injection of human primary effusion lymphoma cells or associated macrophages into severe combined immunodeficient mice causes murine lymphomas. Cancer Res 62: 5536-5542. PubMed: 12359765.
7. Lamers SL, Fogel GB, Huysentruyt LC, McGrath MS,. (2010) HIV-1 nef protein visits B-cells via macrophage nanotubes: a mechanism for AIDS-related lymphoma pathogenesis? Curr HIV Res 8: 638-640. doi:10.2174/157016210794088209. PubMed: 21067513.
8. Müller G, Höpken UE, Stein H, Lipp M, (2002) Systemic immunoregulatory and pathogenic functions of homeostatic chemokine receptors. J Leukoc Biol 72: 1-8. PubMed: 12101256.
9. Hansen A, Lipsky PE, Dörner T, (2007) B cells in Sjogren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissue. Arthritis Res Ther 9: 218. doi:10.1186/ar2210. PubMed: 17697366.
10. Shi K, Hayashida K, Kaneko M, Hashimoto J, Tomita T, et al. (2001) Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients. J Immunol 166: 650-655. PubMed: 11123349.
11. Widney DP, Breen EC, Boscardin WJ, Kitchen SG, Alcantar JM, et al. (2005) Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection. J Interferon Cytokine Res 25: 702-706. doi:10.1089/jir.2005.25.702. PubMed: 16318584.
12. Cagigi A, Mowafi F, Phuong Dang LV, Tenner-Racz K, Atlas A, et al. (2008) Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B-cells during chronic HIV-1 infection. Blood 112: 4401-4410. doi:10.1182/blood-2008-02-140426. PubMed: 18780835.
13. Förster R, Schweigard G, Johann S, Emrich T, Kremmer E, et al. (1997) Abnormal expression of the B-cell homing chemokine receptor BLR1 during the progression of acquired immunodeficiency syndrome. Blood 90: 520-525. PubMed: 9226150.
14. Chan CC, Shen D, Hackett JJ, Buggage RR, Tuaillon N, (2003) Expression of chemokine receptors, CXCR4 and CXCR5, and chemokines, BLC and SDF-1, in the eyes of patients with primary intraocular lymphoma. Ophthalmology 110: 421-426. doi:10.1016/S0161-6420(02)01737-2. PubMed: 12578791.
15. Husson H, Freedman AS, Cardoso AA, Schultze J, Munoz O, et al. (2002) CXCL13 (BCA-1) is produced by follicular lymphoma cells: role in the accumulation of malignant B cells. Br J Haematol 119: 492-495. doi:10.1046/j.1365-2141.2002.03832.x. PubMed: 12406091.
16. Han JI, Huang NN, Kim DU, Kehrl JH, (2006) RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization. J Leukoc Biol 79: 1357-1368. doi:10.1189/jlb.1105693. PubMed: 16565322.
17. Trentin L, Cabrelle A, Facco M, Carollo D, Miorin M, et al. (2004) Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas. Blood 104: 502-508. doi:10.1182/blood-2003-09-3103. PubMed: 15001469.
18. Widney DP, Gui D, Popoviciu LM, Said JW, Breen EC, et al. (2010) Expression and function of the chemokine, CXCL13, and its receptor, CXCR5, in AIDS-associated non-Hodgkin's lymphoma. AIDS Res Treat, 2010: 164586. PubMed: 21490903.
19. Ng VL, Hurt MH, Fein CL, Khayam-Bashi F, Marsh J, et al. (1994) IgMs produced by two acquired immune deficiency syndrome lymphoma cell lines: Ig binding specificity and VH-gene putative somatic mutation analysis. Blood 83: 1067-1078. PubMed: 8111047.
20. Widney D, Boscardin WJ, Kasravi A, Martínez-Maza O, (2003) Expression and function of CD28 on Epstein-Barr virus-positive B cell lines and AIDS-associated non-Hodgkin's lymphoma cell lines. Tumour Biol 24: 82-93. doi:10.1159/000071081. PubMed: 12853703.
21. Loening AM, Gambhir SS, (2003) AMIDE: a free software tool for multimodality medical image analysis. Mol Imaging 2: 131-137. doi:10.1162/153535003322556877. PubMed: 14649056.
22. Olafsen T, Betting D, Kenanova VE, Salazar FB, Clarke P, et al. (2009) Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas. J Nucl Med 50: 1500-1508. doi:10.2967/jnumed.108.060426. PubMed: 19690034.
23. Piovan E, Tosello V, Indraccolo S, Cabrelle A, Baesso I, et al. (2005) Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation. Blood 105: 931-939. PubMed: 15454484.
24. Kahnt K, Mätz-Rensing K, Hofmann P, Stahl-Hennig C, Kaup FJ, (2002) SIV-associated lymphomas in rhesus monkeys (Macaca mulatta) in comparison with HIV-associated lymphomas. Vet Pathol 39: 42-55. doi:10.1354/vp.39-1-42. PubMed: 12102218.
25. Laurence J, Astrin SM (1991) Human immunodeficiency virus induction of malignant transformation in human B lymphocytes. Proc Natl Acad Sci U.S.A. 88: 7635-7639.
26. Knowles DM, (2003) Etiology and pathogenesis of AIDS-related non-Hodgkin's lymphoma. Hematol/Oncol Clin North Am 17: 785-820. doi:10.1016/S0889-8588(03)00050-9.
27. Bertolini F, Fusetti L, Mancuso P, Gobbi A, Corsini C, et al. (2000) Endostatin, an antiangiogenic drug, induces tumor stabilization after chemotherapy or anti-CD20 therapy in a NOD/SCID mouse model of human high-grade non-Hodgkin lymphoma. Blood 96: 282-287. PubMed: 10891463.
28. Daniel D, Yang B, Lawrence DA, Totpal K, Balter I, et al. (2007) Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts. Blood 110: 4037-4046. doi:10.1182/blood-2007-02-076075. PubMed: 17724141.
29. Bertolini F, Dell'Agnola C, Mancuso P, Rabascio C, Burlini A, et al. (2002) CXCR4 neutralization, a novel therapeutic approach for non-Hodgkin's lymphoma. Cancer Res 62: 3106-3112. PubMed: 12036921.
30. Breen EC, van der Meijden M, Cumberland W, Kishimoto T, Detels R, et al. (1999) The development of AIDS-associated Burkitt's/small noncleaved cell lymphoma is preceded by elevated serum levels of Interleukin 6. Clin Immunol 92: 293-299. doi:10.1006/clim.1999.4760. PubMed: 10479534.
31. Yawetz S, Cumberland WG, van der Meyden M, Martínez-Maza O, (1995) Elevated serum levels of soluble CD23 (sCD23) precede the appearance of acquired immunodeficiency syndrome--associated non-Hodgkin's lymphoma. Blood 85: 1843-1849. PubMed: 7703491.
32. R&D Systems Inc., Minneapolis, MN (2009). Tech Literature on Recombinant Mouse CXCL 13Cat. #470-BC. Available: http://www.rndsystems.com.
33. Meijer J, Zeelenberg IS, Sipos B, Roos E, (2006) The CXCR5 chemokine receptor is expressed by carcinoma cells and promotes growth of colon carcinoma in the liver. Cancer Res 66: 9576-9582. doi:10.1158/0008-5472.CAN-06-1507. PubMed: 17018614.
34. Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, et al. (1995) Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol 154: 180-191. PubMed: 7995938.
35. Greiner DL, Hesselton RA, Shultz LD, (1998) SCID mouse models of human stem cell engraftment. Stem Cells 16: 166-177. doi:10.1002/stem.160166. PubMed: 9617892.