Abnormal expression of the B-cell homing chemokine receptor BLR1 during the progression of acquired immunodeficiency syndrome

Blood

Volumn 90, Issue 2, 1997, Pages 520-525

  Förster, Reinhold ^a   Schweigard, Georgina ^b   Johann, Sabine ^b   Emrich, Thomas ^b   Kremmer, Elisabeth ^b   Nerl, Christoph ^b   Lipp, Martin ^b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GENE EXPRESSION; GERMINAL CENTER; HELPER CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LYMPH FOLLICLE; LYMPHOCYTE SUBPOPULATION; LYMPHOID TISSUE; MAJOR CLINICAL STUDY; MEMORY CELL; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 1842333856     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.2.520.520_520_525     Document Type: Article

References (40)

1. Fauci AS: Multifactorial nature of human immunodeficiency virus disease: Implications for therapy. Science 262:1011, 1993
2. Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowitz M: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373:123, 1995
3. Wei X, Ghosh SK, Taylor ME, Johnson VA, Emini EA, Deutsch P, Lifson JD, Bonhoeffer S, Nowak MA, Hahn BH, Saag MS, Shaw GM: Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373:117, 1995
4. Pantaleo G, Graziosi C, Demarest JF, Butini L, Montroni M, Fox CH, Orenstein JM, Kotler DP, Fauci AS: HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 362:355, 1993
5. Embretson J, Zupancic M, Ribas JL, Burke A, Racz P, Tenner Racz K, Haase AT: Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 362:359, 1993
6. Piatak M Jr, Saag MS, Yang LC, Clark SJ, Kappes JC, Luk KC, Hahn BH, Shaw GM, Lifson JD: High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR. Science 259:1749, 1993
7. Feng Y, Broder CC, Kennedy PE, Berger EA: HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272:872, 1996
8. Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA: CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272:1955, 1996
9. Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J: The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1135, 1996
10. Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR: Identification of a major co-receptor for primary isolates of HIV-1. Nature 381:661, 1996
11. Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC, Parmentier M, Collman RG, Doms RW: A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 85:1149, 1996
12. Dragic T, Litwin V, Allaway GP, Martin SR, Huang Y, Nagashima KA, Cayanan C, Maddon PJ, Koup RA, Moore JP, Paxton WA: HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 381:667, 1996
13. Ashorn PA, Berger EA, Moss B: Human immunodeficiency virus envelope glycoprotein/CD4-mediated fusion of nonprimate cells with human cells. J Virol 64:2149, 1990
14. Maddon PJ, Dalgleish AG, McDougal JS, Clapham PR, Weiss RA, Axel R: The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47:333, 1986
15. Murphy PM: The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol 12:593, 1994
16. Baggiolini M, Dewald B, Moser B: Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv Immunol 55:97, 1994
17. Dobner T, Wolf I, Emrich T, Lipp M: Differentiation-specific expression of a novel G protein-coupled receptor from Burkitt's lymphoma. Eur J Immunol 22:2795, 1992
18. Kaiser E, Förster R, Wolf I, Ebensperger C, Kuehl WM, Lipp M: The G protein-coupled receptor BLR1 is involved in murine B cell differentiation and is also expressed in neuronal tissues. Eur J Immunol 23:2532, 1993
19. Förster R, Emrich T, Kremmer E, Lipp M: Expression of the G-protein-coupled receptor BLR1 defines mature recirculating B cells and a subset of T memory helper cells. Blood 84:830, 1994
20. Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzanaseisdedos F, Schwartz O, Heard JM, Clarklewis I, Legler DF, Loetscher M, Baggiolini M, Moser B: The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T cell line adapted HIV-1. Nature 382:833, 1996
21. Bleul CC, Farzan M, Choe H, Parolin C, Clarklewis I, Sodroski J, Springer TA: The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/Fusin and blocks HIV-1 entry. Nature 382:829, 1996
22. Förster R, Mattis EA, Kremmer E, Wolf E, Brem G, Lipp M: A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037, 1996
23. Armstrong JA, Dawkins RL, Horne R: Retroviral infection of accessory cells and the immunological paradox in AIDS. Immunol Today 6:121, 1985
24. Emilie D, Peuchmaur M, Maillot MC, Crevon MC, Brousse N, Delfraissy JF, Dormont J, Galanaud P: Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes. J Clin Invest 86:148, 1990
25. Fox CH, Tenner Racz K, Racz P, Firpo A, Pizzo PA, Fauci AS: Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA. J Infect Dis 164:1051, 1991
26. Spiegel H, Herbst H, Niedobitek G, Foss HD, Stein H: Follicular dendritic cells are a major reservoir for human immunodeficiency virus type 1 in lymphoid tissues facilitating infection of CD4+ T-helper cells. Am J Pathol 140:15, 1992
27. Tenner-Racz K, Racz P, Dietrich M, Kern P: Altered follicular dendritic cells and virus-like particles in AIDS and AIDS-related lymphadenopathy. Lancet 1:105, 1985
28. Redfield RR, Wright DC, Tramont EC: The Walter Reed staging classification for HTLV-III/LAV infection. N Engl J Med 314:131, 1986
29. Kabelitz D, Pechhold K, Bender A, Wesselborg S, Wesch D, Friese K, Janssen O: Activation and activation-driven death of human gamma/delta T cells. Immunol Rev 120:71, 1991
30. Schuurman HJ, Krone WJ, Broekhuizen R, Goudsmit J: Expression of RNA and antigens of human immunodeficiency virus type-1 (HIV-1) in lymph nodes from HIV-1 infected individuals. Am J Pathol 133:516, 1988
31. Koopman G, Pals ST: Cellular interactions in the germinal center: Role of adhesion receptors and significance for the pathogenesis of AIDS and malignant lymphoma. Immunol Rev 126:21, 1992
32. Lane HC, Masur H, Edgar LC, Whalen G, Rook AH, Fauci AS: Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med 309:453, 1983
33. Amadori A, De Rossi A, Faulkner Valle GP, Chieco Bianchi L: Spontaneous in vitro production of virus-specific antibody by lymphocytes from HIV-infected subjects. Clin Immunol Immunopathol 46:342, 1988
34. Amadori A, Chieco Bianchi L: B-cell activation and HIV-1 infection: Deeds and misdeeds. Immunol Today 11:374, 1990
35. Macchia D, Almerigogna F, Parronchi P, Ravina A, Maggi E. Romagnani S: Membrane tumour necrosis factor-alpha is involved in the polyclonal B-cell activation induced by HIV-infected human T cells. Nature 363:464, 1993
36. Akbar AN, Terry L, Timms A, Beverley PC, Janossy G: Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol 140:2171, 1988
37. Helbert MR, L'age SJ, Mitchison NA: Antigen presentation, loss of immunological memory and AIDS. Immunol Today 14:340, 1993
38. Falini B, Flenghi L, Pileri S, Pelicci P, Fagioli M, Martelli MF, Moretta L, Ciccone E: Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues. J Immunol 143:2480, 1989
39. Augustin A, Kubo RT, Sim GK: Resident pulmonary lymphocytes expressing the gamma/delta T-cell receptor. Nature 340:239, 1989
40. Perera MK, Carter R, Goonewardene R, Mendis KN: Transient increase in circulating gamma/delta T cells during Plasmodium vivax malarial paroxysms. J Exp Med 179:311, 1994