Gene Expression Profiling of Histiocytic Sarcomas in a Canine Model: The Predisposed Flatcoated Retriever Dog

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Boerkamp, Kim M ^a   van der Kooij, Marieke ^a   van Steenbeek, Frank G ^a   van Wolferen, Monique E ^a   Groot Koerkamp, Marian J A ^b   van Leenen, Dik ^b   Grinwis, Guy C M ^a   Penning, Louis C ^a   Wiemer, Erik A C ^c   Rutteman, Gerard R ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

THY 1 ANTIGEN; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL TISSUE; ARTICLE; CANCER SUSCEPTIBILITY; CD90 GENE; COL3A1 GENE; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DISSEMINATED CANCER; DNA REPAIR; DNA REPLICATION; DOG; DOWN REGULATION; ENPEP GENE; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION; GTSF1 GENE; HISTIOCYTIC SARCOMA; ITGAD GENE; LUM GENE; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PPBP GENE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SOFT TISSUE SARCOMA; SPIC GENE; TUMOR GENE; UPREGULATION; VALIDATION PROCESS; VCAM1 GENE;

ANIMALS; DISEASE MODELS, ANIMAL; DOGS; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; HISTIOCYTIC SARCOMA; HUMANS; MALE; SPLEEN;

EID: 84881001298     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071094     Document Type: Article

References (57)

1. Shearin AL, Hedan B, Cadieu E, Erich SA, Schmidt EV, et al. (2012) The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer. Cancer Epidemiol Biomarkers Prev. 10.1158/1055-9965.EPI-12-0190-T.
2. Dobson J, Hoather T, McKinley TJ, Wood JL, (2009) Mortality in a cohort of flat-coated retrievers in the UK. Vet Comp Oncol 7: 115-121 10.1111/j.1476-5829.2009.00181.x.
3. Fidel J, Schiller I, Hauser B, Jausi Y, Rohrer-Bley C, et al. (2006) Histiocytic sarcomas in flat-coated retrievers: A summary of 37 cases (november 1998-march 2005). Vet Comp Oncol 4: 63-74 10.1111/j.1476-5810.2006.00090.x.
4. Fulmer AK, Mauldin GE (2007) Canine histiocytic neoplasia: An overview. Can Vet J 48: 1041-3, 1046-50.
5. Scott DW, Miller WH Jr, Tasker JB, Schultz RD, Meuten DJ, (1979) Lymphoreticular neoplasia in a dog resembling malignant histiocytosis (histiocytic medullary reticulosis) in man. Cornell Vet 69: 176-197.
6. Affolter VK, Moore PF, (2002) Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs. Vet Pathol 39: 74-83.
7. Moore PF, Affolter VK, Vernau W, (2006) Canine hemophagocytic histiocytic sarcoma: A proliferative disorder of CD11d+ macrophages. Vet Pathol 43: 632-645 10.1354/vp.43-5-632.
8. Constantino-Casas F, Mayhew D, Hoather TM, Dobson JM, (2011) The clinical presentation and histopathologic-immunohistochemical classification of histiocytic sarcomas in the flat coated retriever. Vet Pathol 48: 764-771 10.1177/0300985810385153.
9. Beverley PC, Egeler RM, Arceci RJ, Pritchard J, (2005) The nikolas symposia and histiocytosis. Nat Rev Cancer 5: 488-494 10.1038/nrc1632.
10. Hedan B, Thomas R, Motsinger-Reif A, Abadie J, Andre C, et al. (2011) Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior. BMC Cancer 11: 201 10.1186/1471-2407-11-201.
11. Abadie J, Hedan B, Cadieu E, De Brito C, Devauchelle P, et al. (2009) Epidemiology, pathology, and genetics of histiocytic sarcoma in the bernese mountain dog breed. J Hered 100Suppl 1: S19-27 10.1093/jhered/esp039.
12. Pileri SA, Grogan TM, Harris NL, Banks P, Campo E, et al. (2002) Tumours of histiocytes and accessory dendritic cells: An immunohistochemical approach to classification from the international lymphoma study group based on 61 cases. Histopathology 41: 1-29.
13. Meuten DJ (2002) Tumors in domestic animals.: Iowa State Press; A Blackwell Publishing Company. 788 p.
14. Sterenczak KA, Kleinschmidt S, Wefstaedt P, Eberle N, Hewicker-Trautwein M, et al. (2011) Quantitative PCR and immunohistochemical analyses of HMGB1 and RAGE expression in canine disseminated histiocytic sarcoma (malignant histiocytosis). Anticancer Res 31: 1541-1548.
15. Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 98: 10869-10874 10.1073/pnas.191367098.
16. Baird K, Davis S, Antonescu CR, Harper UL, Walker RL, et al. (2005) Gene expression profiling of human sarcomas: Insights into sarcoma biology. Cancer Res 65: 9226-9235 10.1158/0008-5472.CAN-05-1699.
17. Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, et al. (2005) Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438: 803-819 10.1038/nature04338.
18. Tamburini BA, Phang TL, Fosmire SP, Scott MC, Trapp SC, et al. (2010) Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma. BMC Cancer 10: 619 10.1186/1471-2407-10-619.
19. Mahoney JA, Fisher JC, Snyder SA, Hauck ML, (2010) Feasibility of using gene expression analysis to study canine soft tissue sarcomas. Mamm Genome 21: 577-582 10.1007/s00335-010-9298-y.
20. Tamburini BA, Trapp S, Phang TL, Schappa JT, Hunter LE, et al. (2009) Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed. PLoS One 4: e5549 10.1371/journal.pone.0005549.
21. Paoloni M, Khanna C, (2008) Translation of new cancer treatments from pet dogs to humans. Nat Rev Cancer 8: 147-156 10.1038/nrc2273.
22. Hoffman MM, Birney E, (2007) Estimating the neutral rate of nucleotide substitution using introns. Mol Biol Evol 24: 522-531 10.1093/molbev/msl179.
23. Danilenko DM, Rossitto PV, Van der Vieren M, Le Trong H, McDonough SP, et al. (1995) A novel canine leukointegrin, alpha d beta 2, is expressed by specific macrophage subpopulations in tissue and a minor CD8+ lymphocyte subpopulation in peripheral blood. J Immunol 155: 35-44.
24. Opitz L, Salinas-Riester G, Grade M, Jung K, Jo P, et al. (2010) Impact of RNA degradation on gene expression profiling. BMC Med Genomics 3: 36 10.1186/1755-8794-3-36.
25. Roepman P, Wessels LF, Kettelarij N, Kemmeren P, Miles AJ, et al. (2005) An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas. Nat Genet 37: 182-186 10.1038/ng1502.
26. van de Peppel J, Kemmeren P, van Bakel H, Radonjic M, van Leenen D, et al. (2003) Monitoring global messenger RNA changes in externally controlled microarray experiments. EMBO Rep 4: 387-393 10.1038/sj.embor.embor798.
27. Yang YH, Dudoit S, Luu P, Lin DM, Peng V, et al. (2002) Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15.
28. Margaritis T, Lijnzaad P, van Leenen D, Bouwmeester D, Kemmeren P, et al. (2009) Adaptable gene-specific dye bias correction for two-channel DNA microarrays. Mol Syst Biol 5: 266 10.1038/msb.2009.21.
29. Wu H, Kerr M, Cui X, Churchill G (2003) MAANOVA: A software package for the analysis of spotted cDNA microarray experiments. In: Anonymous The Analysis of Gene Expression Data. 313-313-341.
30. Schlotter YM, Veenhof EZ, Brinkhof B, Rutten VP, Spee B, et al. (2009) A GeNorm algorithm-based selection of reference genes for quantitative real-time PCR in skin biopsies of healthy dogs and dogs with atopic dermatitis. Vet Immunol Immunopathol 129: 115-118 10.1016/j.vetimm.2008.12.004.
31. Brinkhof B, Spee B, Rothuizen J, Penning LC, (2006) Development and evaluation of canine reference genes for accurate quantification of gene expression. Anal Biochem 356: 36-43 10.1016/j.ab.2006.06.001.
32. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
33. van Steenbeek FG, Van den Bossche L, Grinwis GC, Kummeling A, van Gils IH, et al. (2013) Aberrant gene expression in dogs with portosystemic shunts. PLoS One 8: e57662 10.1371/journal.pone.0057662; 10.1371/journal.pone.0057662.
34. van Steenbeek FG, Spee B, Penning LC, Kummeling A, van Gils IH, et al. (2013) Altered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs. PLoS One 8: e57973 10.1371/journal.pone.0057973; 10.1371/journal.pone.0057973.
35. Kohyama M, Ise W, Edelson BT, Wilker PR, Hildner K, et al. (2009) Role for spi-C in the development of red pulp macrophages and splenic iron homeostasis. Nature 457: 318-321 10.1038/nature07472.
36. Osborn L, Hession C, Tizard R, Vassallo C, Luhowskyj S, et al. (1989) Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 59: 1203-1211.
37. Falkenburg JH, Koning F, Duinkerken N, Fibbe WE, Voogt PJ, et al. (1986) Expression of CD11, CDw15, and transferrin receptor antigens on human hematopoietic progenitor cells. Exp Hematol 14: 90-96.
38. Davies FE, Dring AM, Li C, Rawstron AC, Shammas MA, et al. (2003) Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis. Blood 102: 4504-4511 10.1182/blood-2003-01-0016.
39. Matsubara J, Honda K, Ono M, Tanaka Y, Kobayashi M, et al. (2011) Reduced plasma level of CXC chemokine ligand 7 in patients with pancreatic cancer. Cancer Epidemiol Biomarkers Prev 20: 160-171 10.1158/1055-9965.EPI-10-0397.
40. Seya T, Tanaka N, Shinji S, Yokoi K, Koizumi M, et al. (2006) Lumican expression in advanced colorectal cancer with nodal metastasis correlates with poor prognosis. Oncol Rep 16: 1225-1230.
41. Sifaki M, Assouti M, Nikitovic D, Krasagakis K, Karamanos NK, et al. (2006) Lumican, a small leucine-rich proteoglycan substituted with keratan sulfate chains is expressed and secreted by human melanoma cells and not normal melanocytes. IUBMB Life 58: 606-610 10.1080/15216540600951605.
42. Troup S, Njue C, Kliewer EV, Parisien M, Roskelley C, et al. (2003) Reduced expression of the small leucine-rich proteoglycans, lumican, and decorin is associated with poor outcome in node-negative invasive breast cancer. Clin Cancer Res 9: 207-214.
43. Vuillermoz B, Khoruzhenko A, D'Onofrio MF, Ramont L, Venteo L, et al. (2004) The small leucine-rich proteoglycan lumican inhibits melanoma progression. Exp Cell Res 296: 294-306 10.1016/j.yexcr.2004.02.005.
44. Shinji S, Tajiri T, Ishiwata T, Seya T, Tanaka N, et al. (2005) Different expression levels of lumican in human carcinoid tumor and neuroendocrine cell carcinoma. Int J Oncol 26: 873-880.
45. D'Onofrio MF, Brezillon S, Baranek T, Perreau C, Roughley PJ, et al. (2008) Identification of beta1 integrin as mediator of melanoma cell adhesion to lumican. Biochem Biophys Res Commun 365: 266-272 10.1016/j.bbrc.2007.10.155.
46. Ishiwata T, Cho K, Kawahara K, Yamamoto T, Fujiwara Y, et al. (2007) Role of lumican in cancer cells and adjacent stromal tissues in human pancreatic cancer. Oncol Rep 18: 537-543.
47. Mori H, Nishida K, Ozaki T, Inoue H, Nakanishi T, (2008) Isolation of a mRNA preferentially expressed in synoviocytes from rheumatoid arthritis that is identical with lumican, which encodes a collagen binding, extracellular matrix protein. 17: 125-126-130.
48. Nikitovic D, Katonis P, Tsatsakis A, Karamanos NK, Tzanakakis GN, (2008) Lumican, a small leucine-rich proteoglycan. IUBMB Life 60: 818-823 10.1002/iub.131.
49. van Kester MS, Borg MK, Zoutman WH, Out-Luiting JJ, Jansen PM, et al. (2012) A meta-analysis of gene expression data identifies a molecular signature characteristic for tumor-stage mycosis fungoides. J Invest Dermatol 132: 2050-2059 10.1038/jid.2012.117.
50. Gueugnon F, Leclercq S, Blanquart C, Sagan C, Cellerin L, et al. (2011) Identification of novel markers for the diagnosis of malignant pleural mesothelioma. Am J Pathol 178: 1033-1042 10.1016/j.ajpath.2010.12.014.
51. Berner JM, Müller CR, Holden M, Wang J, Hovig E, et al. (2006) Sampling effects on gene expression data from a human tumour xenograft. 33: 17-18-30.
52. Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, et al. (2000) Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet 24: 227-235 10.1038/73432.
53. Lu JW, Chang JG, Yeh KT, Chen RM, Tsai JJ, et al. (2011) Overexpression of Thy1/CD90 in human hepatocellular carcinoma is associated with HBV infection and poor prognosis. Acta Histochem 113: 833-838 10.1016/j.acthis.2011.01.001.
54. Mercati F, Pascucci L, Ceccarelli P, Dall'Aglio C, Pedini V, et al. (2009) Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species. Eur J Histochem 53: 159-166.
55. He J, Liu Y, Zhu T, Zhu J, Dimeco F, et al. (2012) CD90 is identified as a candidate marker for cancer stem cells in primary high-grade gliomas using tissue microarrays. Mol Cell Proteomics 11: M111.010744 10.1074/mcp.M111.010744.
56. Parry PV, Engh JA, (2012) CD90 is identified as a marker for cancer stem cells in high-grade gliomas using tissue microarrays. Neurosurgery 70: N23-4 10.1227/01.neu.0000413227.80467.92; 10.1227/01.neu.0000413227.80467.92.
57. Breen M, Modiano JF, (2008) Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans-man and his best friend share more than companionship. Chromosome Res 16: 145-154 10.1007/s10577-007-1212-4.