Canine hemophagocytic histiocytic sarcoma: A proliferative disorder of CD11d+ macrophages

Veterinary Pathology

Volumn 43, Issue 5, 2006, Pages 632-645

  Moore, P F ^a,b   Affolter, V K ^a   Vernau, W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CD1; CD11d; CD18; Dendritic cell; Dogs; Hemophagocytic; Histiocytic sarcoma; Macrophage

Indexed keywords

CD11 ANTIGEN; INTEGRIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; BONE MARROW; DOG; DOG DISEASE; FEMALE; GENE EXPRESSION REGULATION; HISTIOCYTIC LYMPHOMA; LIVER; MACROPHAGE; MALE; METABOLISM; PATHOLOGY; SARCOMA; SPLEEN;

ANIMALS; ANTIGENS, CD11; BONE MARROW; DOG DISEASES; DOGS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTIOCYTIC DISORDERS, MALIGNANT; INTEGRINS; LIVER; MACROPHAGES; MALE; SARCOMA; SPLEEN;

CANIS FAMILIARIS;

EID: 33748611606     PISSN: 03009858     EISSN: 03009858     Source Type: Journal    
DOI: 10.1354/vp.43-5-632     Document Type: Article

References (52)

1. Affolter VK, Moore PF: Canine cutaneous and systemic histiocytosis: reactive histiocytosis of dermal dendritic cells. Am J Dermatopathol 22:40-48, 2000
2. Affolter VK, Moore PF: Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs. Vet Pathol 39:74-83, 2002
3. Banchereau J, Palucka AK: Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 5:296-306, 2005
4. Bentz MH, Magnette J: Hypocholesterolemia during the acute phase of an inflammatory reaction of infectious origin. 120 cases. Rev Med Interne 19:168-172, 1998 [in French]
5. Bologa RM, Levine DM, Parker TS, Cheigh JS, Serur D, Stenzel KH, Rubin AL: Interleukin-6 predicts hypoalbuminemia, hypocholesterolemia, and mortality in hemodialysis patients. Am J Kidney Dis 32:107-114, 1998
6. Brown DE, Thrall MA, Getzy DM, Weiser MG, Ogilvie GK: Cytology of canine malignant histiocytosis. Vet Clin Path 23:118-122, 1994
7. Carr AP, Panciera DL, Kidd L: Prognostic factors for mortality and thromboembolism in canine immune-mediated hemolytic anemia: a retrospective study of 72 dogs. J Vet Intern Med 16:504-509, 2002
8. Catalfamo M, Henkart PA: Perforin and the granule exocytosis cytotoxicity pathway. Curr Opin Immunol 15:522-527, 2003
9. Danilenko DM, Moore PF, Rossitto PV: Canine leukocyte cell adhesion molecules (LeuCAMS): characterization of the CD11/CD18 family. Tissue Antigens 40:13-21, 1992
10. Danilenko DM, Rossitto PV, Van der Vieren M, Le Trong H, McDonough SP, Affolter VK, Moore PF: A novel canine leukointegrin, alpha d beta 2, is expressed by specific macrophage subpopulations in tissue and a minor CD8+ lymphocyte subpopulation in peripheral blood. J Immunol 155:35-44, 1995
11. De Libero G, Mori L: Recognition of lipid antigens by T cells. Nat Rev Immunol 5:485-496, 2005
12. de Saint Basile G, Fischer A: The role of cytotoxicity in lymphocyte homeostasis. Curr Opin Immunol 13:549-554, 2001
13. Ettinger WH Jr, Sun WH, Binkley N, Kouba E, Ershler W: Interleukin-6 causes hypocholesterolemia in middle-aged and old rhesus monkeys. J Gerontol A Biol Sci Med Sci 50:M137-M140, 1995
14. Fadeel B, Orrenius S, Henter JI: Familial hemophagocytic lymphohistiocytosis: too little cell death can seriously damage your health. Leuk Lymphoma 42:13-20, 2001
15. Favara BE: Histopathology of the liver in histiocytosis syndromes. Pediatr Pathol Lab Med 16:413-433, 1996
16. Favara BE, Feller AC, Pauli M, Jaffe ES, Weiss LM, Arico M, Bucsky P, Egeler RM, Elinder G, Gadner H, Gresik M, Henter JI, Imashuku S, Janka-Schaub G, Jaffe R, Ladisch S, Nezelof C, Pritchard J: Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol 29:157-166, 1997
17. Feldmann J, Callebaut I, Raposo G, Certain S, Bacq D, Dumont C, Lambert N, Ouachee-Chardin M, Chedeville G, Tamary H, Minard-Colin V, Vilmer E, Blanche S, Le Deist F, Fischer A, de Saint Basile G: Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell 115:461-473, 2003
18. Feldmann J, Le Deist F, Ouachee-Chardin M, Certain S, Alexander S, Quartier P, Haddad E, Wulffraat N, Casanova JL, Blanche S, Fischer A, de Saint Basile G: Functional consequences of perforin gene mutations in 22 patients with familial haemophagocytic lymphohistiocytosis. Br J Haematol 117:965-972, 2002
19. Fisman DN: Hemophagocytic syndromes and infection. Emerg Infect Dis 6:601-608, 2000
20. Fry MM, Vernau W, Pesavento PA, Bromel C, Moore PF: Hepatosplenic lymphoma in a dog. Vet Pathol 40:556-562, 2003
21. Hackstein H, Thomson AW: Dendritic cells: emerging pharmacological targets of immunosuppressive drugs. Nat Rev Immunol 4:24-34, 2004
22. Hirasa K, Baba E, Kotani T: Hemolytic anemia induced by malignant histiocytosis. Canine Practice 11:46-48, 1984
23. Imashuku S: Clinical features and treatment strategies of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Crit Rev Oncol Hematol 44:259-272, 2002
24. Ishii E, Ohga S, Imashuku S, Kimura N, Ueda I, Morimoto A, Yamamoto K, Yasukawa M: Review of hemophagocytic lymphohistiocytosis (HLH) in children with focus on Japanese experiences. Crit Rev Oncol Hematol 53:209-223, 2005
25. Ishii E, Ueda I, Shirakawa R, Yamamoto K, Horiuchi H, Ohga S, Furuno K, Morimoto A, Imayoshi M, Ogata Y, Zaitsu M, Sako M, Koike K, Sakata A, Takada H, Hara T, Imashuku S, Sasazuki T, Yasukawa M: Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions. Blood 105:3442-3448, 2005
26. Jordan MB, Hildeman D, Kappler J, Marrack P: An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood 104:735-743, 2004
27. Marchal T, Dezutter-Dambuyant C, Fournel C, Magnol JP, Schmitt D: Immunophenotypic and ultrastructural evidence of the langerhans cell origin of the canine cutaneous histiocytoma. Acta Anat (Basel) 153:189-202, 1995
28. Mays MB, Bergeron JA: Cutaneous histiocytosis in dogs. J Am Vet Med Assoc 188:377-381, 1986
29. McDonough SP, Moore PF: Clinical, hematologic, and immunophenotypic characterization of canine large granular lymphocytosis. Vet Pathol 37:637-646, 2000
30. Meunier L, Bata-Csorgo Z, Cooper KD: In human dermis, ultraviolet radiation induces expansion of a CD36+ CD11b+ CD1- macrophage subset by infiltration and proliferation; CD1+ Langerhans-like dendritic antigen-presenting cells are concomitantly depleted. J Invest Dermatol 105:782-788, 1995
31. Meunier L, Gonzalez-Ramos A, Cooper KD: Heterogeneous populations of class II MHC+ cells in human dermal cell suspensions. Identification of a small subset responsible for potent dermal antigen presenting cell activity with features analogous to Langerhans cells. J Immunol 151:4067-4080, 1993
32. Moore P, Affolter V, Olivry T, Schrenzel M: The use of immunological reagents in defining the pathogenesis of canine skin diseases involving proliferation of leukocytes. In: Advances in Veterinary Dermatology, ed. Kwotchka K and Willemse Tvon Tscharner C, pp. 77-94. Butterworth Heinmann, Oxford, 1998
33. Moore PF: Systemic histiocytosis of Bernese mountain dogs. Vet Pathol 21:554-563, 1984
34. Moore PF, Rosin A: Malignant histiocytosis of Bernese mountain dogs. Vet Pathol 23:1-10, 1986
35. Moore PF, Schrenzel MD, Affolter VK, Olivry T, Naydan D: Canine cutaneous histiocytoma is an epidermotropic Langerhans cell histiocytosis that expresses CD1 and specific beta 2-integrin molecules. Am J Pathol 148:1699-1708, 1996
36. Mullauer L, Gruber P, Sebinger D, Buch J, Wohlfart S, Chott A: Mutations in apoptosis genes: a pathogenetic factor for human disease. Mutat Res 488:211-231, 2001
37. Nagata M, Hirata M, Ishida T, Hirata S, Nanko H: Progressive Langerhans cell histiocytosis in a puppy. Vet Derm 11:241-246, 2000
38. Ost A, Nilsson-Ardnor S, Henter JI: Autopsy findings in 27 children with haemophagocytic lymphohistiocytosis. Histopathology 32:310-316, 1998
39. Reimer ME, Troy GC, Warnick LD: Immune-mediated hemolytic anemia: 70 cases (1988-1996). J Am Anim Hosp Assoc 35:384-391, 1999
40. Schalm O: Histiocytic medullary reticulosis. Canine Practice 5:42-45, 1978
41. Shortman K, Caux C: Dendritic cell development: multiple pathways to nature's adjuvants. Stem Cells 15:409-419, 1997
42. Shortman K, Liu YJ: Mouse and human dendritic cell subtypes. Nat Rev Immunol 2:151-161, 2002
43. Spangler WL, Kass PH: Splenic myeloid metaplasia, histiocytosis, and hypersplenism in the dog (65 cases). Vet Pathol 36:583-593, 1999
44. Stepp SE, Dufourcq-Lagelouse R, Le Deist F, Bhawan S, Certain S, Mathew PA, Henter JI, Bennett M, Fischer A, de Saint Basile G, Kumar V: Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science 286:1957-1959, 1999
45. Stockhaus C, Slappendel RJ: Haemophagocytic syndrome with disseminated intravascular coagulation in a dog. J Small Anim Pract 39:203-206, 1998
46. Van der Vieren M, Le Trong H, Wood CL, Moore PF, StJohn T, Staunton DE, Gallatin WM: A novel leukointegrin, alpha d beta 2, binds preferentially to ICAM-3. Immunity 3:683-690, 1995
47. Vernau W, Moore PF: An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction. Vet Immunol Immunopathol 69:145-164, 1999
48. Walton RM, Modiano JF, Thrall MA, Wheeler SL: Bone marrow cytological findings in 4 dogs and a cat with hemophagocytic syndrome. J Vet Intern Med 10:7-14, 1996
49. Warnke RA, Kim H, Dorfman RF: Malignant histiocytosis (histiocytic medullary reticulosis). I. Clinicopatholigic study of 29 cases. Cancer 35:215-230, 1975
50. Weiss DJ: Flow cytometric evaluation of hemophagocytic disorders in canine. Vet Clin Pathol 31:36-41, 2002
51. Wellman ML, Davenport DJ, Morton D, Jacobs RM: Malignant histiocytosis in four dogs. J Am Vet Med Assoc 187:919-921, 1985
52. Zhang B, Ginsburg D: Getting secretory granules ready for prime time. Cell 115:372-373, 2003