PKC and ERK mediate GH-stimulated lipolysis

Journal of Molecular Endocrinology

Volumn 51, Issue 2, 2013, Pages 213-224

  Bergan, Heather E ^a   Kittilson, Jeffrey D ^a   Sheridan, Mark A ^a  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

GH; Hormone sensitive lipase; Lipids; Metabolism; Rainbow trout (oncorhynchus mykiss); Signal transduction

Indexed keywords

GLYCEROL; GROWTH HORMONE; HORMONE SENSITIVE LIPASE; JANUS KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE B; PROTEIN KINASE C; STAT5 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; LIPOLYSIS; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAINBOW TROUT;

GH; HORMONE-SENSITIVE LIPASE; LIPIDS; METABOLISM; RAINBOW TROUT (ONCORHYNCHUS MYKISS); SIGNAL TRANSDUCTION;

ANIMALS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GROWTH HORMONE; HEPATOCYTES; LIPOLYSIS; ONCORHYNCHUS MYKISS; PROTEIN KINASE C; SIGNAL TRANSDUCTION;

EID: 84880989183     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-13-0039     Document Type: Article

References (36)

1. Albalat A, Gomez-Requeni P, Rojas P, Medale F, Kaushik S, Vianen GJ, Van den Thillart G, Gutiérrez J, Perez-Sanchez J & Navarro I 2005 Nutritional and hormonal control of lipolysis in isolated gilthead sea bream (Sparus aurata) adipocytes. American Journal of Physiology 289 R259-R265. (doi:10.1152/ajpregu.00574.2004)
2. Albalat A, Saera-vila A, Capilla E, Gutierrez J, Perez-Sanchez J & Navarro I 2007 Insulin regulation of lipoprotein lipase (LPL) activity and expression in gilthead sea bream (Sparus aurata). Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology 148 151-159. (doi:10.1016/j.cbpb.2007.05.004)
3. Baragali A, Ghè C, Arnoletti E, Granata R, Ghigo E & Muccioli G 2011 Acylated and unacylated ghrelin attenuate isoproterenol-induced lipolysis in isolated rat visceral adipocytes through activation of phosphoinositide 3-kinase g and phosphodiesterase 3B. Biochimica et Biophysica Acta 1811 386-396. (doi:10.1016/j.bbalip.2011.03.001)
4. Bergan HB, Kittilson JD & Sheridan MA 2012 Nutrition-regulated lipolysis in rainbow trout (Oncorhynchus mykiss) is associated with alteration in the ERK, PI3K-Akt, JAK-STAT, and PKC signaling pathways. General and Comparative Endocrinology 176 367-376. (doi:10.1016/j.ygcen.2011.12.013)
5. Berggreen C, Gormand A, Omar B, Degerman E & Goransson O 2009 Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes. American Journal of Physiology 296 E635-E646. (doi:10.1152/ajpendo.90596.2008)
6. Bjornsson BT, Johansson V, Benedet S, Einarsdottir IE, Hildahl J, Agustsson T Jonsson E 2004 Growth hormone endocrinology of salmonids: regulatory mechanisms and mode of action. Fish Physiology and Biochemistry 27 227-242. (doi:10.1023/B:FISH.0000032728.91152.10)
7. Carrel AL & Allen DB 2000 Effects of growth hormone on adipose tissue. Journal of Pediatric Endocrinology & Metabolism 13 1003-1009.
8. Caruso MA & Sheridan MA 2011 New insights into the signaling system and function of insulin in fish. General and Comparative Endocrinology 173227-247. (doi:10.1016/j.ygcen.2011.06.014)
9. Chaves VE, Frasson D & Kawashita NH 2011 Several agents and pathways regulate lipolysis in adipocytes. Biochimie 93 1631-1640. (doi:10.1016/j.biochi.2011.05.018)
10. Chavez JA, Gridley S, Sano H, Lane WS & Lienhard GE 2006 The 47 kDa Akt substrate associates with phosphodiesterase 3B and regulates its level in adipocytes. Biochemical and Biophysical Research Communications 324 1218-1222. (doi:10.1016/j.bbrc.2006.02.091)
11. Fain JN 1980 Hormonal regulation of lipid mobilization from adipose tissue. In Biochemical Action of Hormones, pp 119-203. Ed G Litwack. New York: Academic Press.
12. Fricke K, Heitland A & Maronde E 2004 Cooperative activation of lipolysis by protein kinase A and protein kinase C pathways in 3T3-L1 adipocytes. Endocrinology 145 4940-4947. (doi:10.1210/en.2004-0803)
13. González-Yanes C & Sánchez-Margalet V 2006 Signalling mechanisms regulating lipolysis. Cellular Signalling 18 401-408. (doi:10.1016/ j.cellsig.2005.08.009)
14. Gorin E, Tai L, Honeyman TW & Goodman HM 1990 Evidence for a role of protein kinase C in the stimulation of lipolysis by growth hormone and isoproterenol. Endocrinology 126 2973-2982. (doi:10.1210/ endo-126-6-2973)
15. Greenberg AS, Shen WJ, Muliro K, Patel S, Souza SC, Roth RA & Kraemer FB 2001 Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway. Journal of Biological Chemistry 276 45456-45461. (doi:10.1074/jbc.M104436200)
16. Harmon JS, Michelsen KG & Sheridan MA 1991 Purification and characterization of hepatic triacylglycerol lipase isolated from rainbow trout. Fish Physiology and Biochemistry 9 361-368. (doi:10.1007/BF02265156)
17. Harmon JS, Rieniets LM & Sheridan MA 1993 Glucagon and insulin regulate lipolysis in trout liver by altering phosphorylation of triacylglycerol lipase. American Journal of Physiology 265 255-260.
18. Holsyz M, Derebecka-Holszy N & Trzeciak WH 2011 Transcription of LIPE gene encoding hormone-sensitive lipase/cholesteryl esterase is regulated by SF-1 in human adrenocortical cells: involvement of protein kinase A signal transduction pathway. Journal of Molecular Endocrinology 46 29-36. (doi:10.1677/JME-10-0035)
19. Kittilson JD, Reindl KM & Sheridan MA 2011 Rainbow trout (Oncorhynchus mykiss) possess two hormone-sensitive lipase-encoding mRNAs that are differentially expressed and independently regulated by nutritional state. Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology 158 52-60. (doi:10.1016/j.cbpa.2010.09.010)
20. Lafontan M & Langin D 2009 Lipolysis and lipid mobilization in human adipose tissue. Progress in Lipid Research 48 275-297. (doi:10.1016/ j.plipres.2009.05.001)
21. 0 regulatory region of ovine hormone sensitive lipase (HSL) gene. Gene 427 65-79. (doi:10.1016/j.gene.2008.09.001)
22. Lo JH, Chiou PP, Lin CM & Chen TT 2007 Molecular cloning and expression analysis of rainbow trout (Oncorhynchus mykiss) CCAAT/ enhancer binding protein genes and their response to induction by GH in vitro and in vivo. Journal of Endocrinology 194 393-406. (doi:10.1677/JOE-07-0085)
23. Mommsen TP, Moon TW & Walsh PJ 1994 Hepatocytes: isolation, maintenance, and utilization. In Biochemistry and Molecular Biology of Fish, pp 355-373. Eds PW Hochachka & TP Mommsen. New York: Elsevier Science.
24. Norbeck LA, Kittilson JD & Sheridan MA 2007 Resolving the growth promoting and metabolic effects of growth hormone: differential regulation of GH-IGF-I system components. General and Comparative Endocrinology 151 332-341. (doi:10.1016/j.ygcen.2007.01.039)
25. Norrelund H 2005 The metabolic role of growth hormone in humans with particular reference to fasting. Growth Hormone & IGF Research 15 95-122. (doi:10.1016/j.ghir.2005.02.005)
26. O'Connor PK, Reich B & Sheridan MA 1993 Growth hormone stimulates hepatic lipid mobilization in rainbow trout, Oncorhynchus mykiss. Journal of Comparative Physiology 163 427-431.
27. Piwien-Pilipuk G, Huo JS & Schwatz J 2002 Growth hormone signal transduction. Journal of Pediatric Endocrinology & Metabolism 15 771-786.
28. Reindl KM & Sheridan MA 2012 Peripheral regulation of the growth hormone-insulin-like growth factor system in fish and other vertebrates. Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology 163 231-245. (doi:10.1016/j.cbpa.2012.08.003)
29. Reindl KM, Kittilson JD, Bergan HE & Sheridan MA 2011 Growth hormone stimulated insulin-like growth factor-1 expression in rainbow trout (Oncorhynchus mykiss) hepatocytes is mediated by ERK, PI3K-AKT, and JAK-STAT. American Journal of Physiology 301 R236-R243.
30. Sheridan MA 1988 Lipid dynamics in fish: aspects of absorption, transportation, deposition and mobilization. Comparative Biochemistry and Physiology. B, Comparative Biochemistry 90 679-690. (doi:10.1016/ 0305-0491(88)90322-7)
31. Sheridan MA 1989 Alterations in lipid metabolism accompanying smoltification and seawater adaptation of salmonid fish. Aquaculture 82191-203. (doi:10.1016/0044-8486(89)90408-0)
32. Sheridan MA 1994 Regulation of lipid metabolism in poikilothermic vertebrates. Comparative Biochemistry and Physiology. B, Comparative Biochemistry 107 495-508. (doi:10.1016/0305-0491(94)90176-7)
33. Waters MJ, Hoang HN, Fairlie DP, Pelekanos RA & Brown RJ 2006 New insights into growth hormone action. Journal of Molecular Endocrinology 361-7. (doi:10.1677/jme.1.01933)
34. Watt MJ & Steinberg GR 2008 Regulation and function of triacylglycerol lipases in cellular metabolism. Biochemical Journal 414 313-325. (doi:10.1042/BJ20080305)
35. Watt MJ & Spriet LL 2010 Triacylglycerol lipase and metabolic control: implication for health and disease. American Journal of Physiology 299 E162-E168. (doi:10.1152/ajpendo.00698.2009)
36. Yeaman SJ 2004 Hormone-sensitive lipase new roles for an old enzyme. Biochemical Journal 79 11-22. (doi:10.1042/BJ20031811)