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Volumn 8, Issue 8, 2013, Pages

Variation in Trans-3′-Hydroxycotinine Glucuronidation Does Not Alter the Nicotine Metabolite Ratio or Nicotine Intake

Author keywords

[No Author keywords available]

Indexed keywords

3' HYDROXYCOTININE; CYTOCHROME P450 2A6; NICOTINE;

EID: 84880970493     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070938     Document Type: Article
Times cited : (38)

References (38)
  • 1
    • 0021882484 scopus 로고
    • Nicotine renal excretion rate influences nicotine intake during cigarette smoking
    • Benowitz NL, Jacob P 3rd (1985) Nicotine renal excretion rate influences nicotine intake during cigarette smoking. J Pharmacol Exp Ther 234: 153-155.
    • (1985) J Pharmacol Exp Ther , vol.234 , pp. 153-155
    • Benowitz, N.L.1    Jacob 3rd, P.2
  • 2
    • 0037116614 scopus 로고    scopus 로고
    • Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans
    • Benowitz NL, Perez-Stable EJ, Herrera B, Jacob P 3rd (2002) Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans. J Natl Cancer Inst 94: 108-115.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 108-115
    • Benowitz, N.L.1    Perez-Stable, E.J.2    Herrera, B.3    Jacob 3rd, P.4
  • 3
    • 0032565878 scopus 로고    scopus 로고
    • Nicotine metabolism defect reduces smoking
    • Pianezza ML, Sellers EM, Tyndale RF, (1998) Nicotine metabolism defect reduces smoking. Nature 393: 750.
    • (1998) Nature , vol.393 , pp. 750
    • Pianezza, M.L.1    Sellers, E.M.2    Tyndale, R.F.3
  • 4
    • 0030885491 scopus 로고    scopus 로고
    • A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes
    • Messina ES, Tyndale RF, Sellers EM, (1997) A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes. J Pharmacol Exp Ther 282: 1608-1614.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1608-1614
    • Messina, E.S.1    Tyndale, R.F.2    Sellers, E.M.3
  • 5
    • 0027987497 scopus 로고
    • Metabolism of nicotine to cotinine studied by a dual stable isotope method
    • Benowitz NL, Jacob P 3rd (1994) Metabolism of nicotine to cotinine studied by a dual stable isotope method. Clin Pharmacol Ther 56: 483-493.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 483-493
    • Benowitz, N.L.1    Jacob 3rd, P.2
  • 6
    • 5544281923 scopus 로고    scopus 로고
    • Characterization of CYP2A6 involved in 3′-hydroxylation of cotinine in human liver microsomes
    • Nakajima M, Yamamoto T, Nunoya K, Yokoi T, Nagashima K, et al. (1996) Characterization of CYP2A6 involved in 3′-hydroxylation of cotinine in human liver microsomes. J Pharmacol Exp Ther 277: 1010-1015.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1010-1015
    • Nakajima, M.1    Yamamoto, T.2    Nunoya, K.3    Yokoi, T.4    Nagashima, K.5
  • 7
    • 84876565867 scopus 로고    scopus 로고
    • The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex
    • Zhu AZ, Renner CC, Hatsukami DK, Swan GE, Lerman C, et al. (2013) The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex. Cancer Epidemiol Biomarkers Prev 22: 708-718.
    • (2013) Cancer Epidemiol Biomarkers Prev , vol.22 , pp. 708-718
    • Zhu, A.Z.1    Renner, C.C.2    Hatsukami, D.K.3    Swan, G.E.4    Lerman, C.5
  • 8
  • 9
    • 84887208686 scopus 로고    scopus 로고
    • Metabolism of Drugs and Other Xenobiotics: Wiley-VCH Verlag GmbH & Co. KGaA
    • Zhu AZX, Tyndale RF (2012) Nicotine Metabolism and its Implications. Metabolism of Drugs and Other Xenobiotics: Wiley-VCH Verlag GmbH & Co. KGaA. 465-492.
    • (2012) Nicotine Metabolism and its Implications , pp. 465-492
    • Zhu, A.Z.X.1    Tyndale, R.F.2
  • 10
    • 3042563552 scopus 로고    scopus 로고
    • Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity
    • Dempsey D, Tutka P, Jacob P 3rd, Allen F, Schoedel K, et al (2004) Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity. Clin Pharmacol Ther 76: 64-72.
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 64-72
    • Dempsey, D.1    Tutka, P.2    Jacob 3rd, P.3    Allen, F.4    Schoedel, K.5
  • 11
    • 84872138863 scopus 로고    scopus 로고
    • Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation
    • Zhu AZ, Binnington MJ, Renner CC, Lanier AP, Hatsukami DK, et al. (2013) Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation. Carcinogenesis 34: 93-101.
    • (2013) Carcinogenesis , vol.34 , pp. 93-101
    • Zhu, A.Z.1    Binnington, M.J.2    Renner, C.C.3    Lanier, A.P.4    Hatsukami, D.K.5
  • 12
    • 48949107504 scopus 로고    scopus 로고
    • Toward personalized therapy for smoking cessation: a randomized placebo-controlled trial of bupropion
    • Patterson F, Schnoll RA, Wileyto EP, Pinto A, Epstein LH, et al. (2008) Toward personalized therapy for smoking cessation: a randomized placebo-controlled trial of bupropion. Clin Pharmacol Ther 84: 320-325.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 320-325
    • Patterson, F.1    Schnoll, R.A.2    Wileyto, E.P.3    Pinto, A.4    Epstein, L.H.5
  • 13
    • 67349284846 scopus 로고    scopus 로고
    • Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers
    • Ho MK, Mwenifumbo JC, Al Koudsi N, Okuyemi KS, Ahluwalia JS, et al. (2009) Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers. Clin Pharmacol Ther 85: 635-643.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 635-643
    • Ho, M.K.1    Mwenifumbo, J.C.2    Al Koudsi, N.3    Okuyemi, K.S.4    Ahluwalia, J.S.5
  • 14
    • 33744519035 scopus 로고    scopus 로고
    • Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation
    • Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, et al. (2006) Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. Clin Pharmacol Ther 79: 600-608.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 600-608
    • Lerman, C.1    Tyndale, R.2    Patterson, F.3    Wileyto, E.P.4    Shields, P.G.5
  • 16
    • 0034746463 scopus 로고    scopus 로고
    • Trans-3′-hydroxycotinine: disposition kinetics, effects and plasma levels during cigarette smoking
    • Benowitz NL, Jacob P 3rd
    • Benowitz NL, Jacob P 3rd (2001) Trans-3′-hydroxycotinine: disposition kinetics, effects and plasma levels during cigarette smoking. Br J Clin Pharmacol 51: 53-59.
    • (2001) Br J Clin Pharmacol , vol.51 , pp. 53-59
  • 17
    • 33747673619 scopus 로고    scopus 로고
    • Within-subject variation of the salivary 3HC/COT ratio in regular daily smokers: prospects for estimating CYP2A6 enzyme activity in large-scale surveys of nicotine metabolic rate
    • Lea RA, Dickson S, Benowitz NL, (2006) Within-subject variation of the salivary 3HC/COT ratio in regular daily smokers: prospects for estimating CYP2A6 enzyme activity in large-scale surveys of nicotine metabolic rate. J Anal Toxicol 30: 386-389.
    • (2006) J Anal Toxicol , vol.30 , pp. 386-389
    • Lea, R.A.1    Dickson, S.2    Benowitz, N.L.3
  • 19
    • 85027958455 scopus 로고    scopus 로고
    • Glucuronidation of trans-3′-hydroxycotinine by UGT2B17 and UGT2B10
    • Chen G, Giambrone NE, Lazarus P, (2012) Glucuronidation of trans-3′-hydroxycotinine by UGT2B17 and UGT2B10. Pharmacogenet Genomics 22: 183-190.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 183-190
    • Chen, G.1    Giambrone, N.E.2    Lazarus, P.3
  • 21
    • 57149123783 scopus 로고    scopus 로고
    • Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis
    • Yang TL, Chen XD, Guo Y, Lei SF, Wang JT, et al. (2008) Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. American journal of human genetics 83: 663-674.
    • (2008) American Journal of Human Genetics , vol.83 , pp. 663-674
    • Yang, T.L.1    Chen, X.D.2    Guo, Y.3    Lei, S.F.4    Wang, J.T.5
  • 22
    • 77957354096 scopus 로고    scopus 로고
    • Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms
    • Chen G, Giambrone NE Jr, Dluzen DF, Muscat JE, Berg A, et al. (2010) Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms. Cancer research 70: 7543-7552.
    • (2010) Cancer Research , vol.70 , pp. 7543-7552
    • Chen, G.1    Giambrone Jr., N.E.2    Dluzen, D.F.3    Muscat, J.E.4    Berg, A.5
  • 23
    • 27444436445 scopus 로고    scopus 로고
    • Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes
    • Lazarus P, Zheng Y, Aaron Runkle E, Muscat JE, Wiener D, (2005) Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes. Pharmacogenetics and genomics 15: 769-778.
    • (2005) Pharmacogenetics and Genomics , vol.15 , pp. 769-778
    • Lazarus, P.1    Zheng, Y.2    Aaron Runkle, E.3    Muscat, J.E.4    Wiener, D.5
  • 24
    • 84861141628 scopus 로고    scopus 로고
    • CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people
    • Binnington JM, Zhu AZ, Renner CC, Lanier AP, Hatsukami DK, et al. (2012) CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people. Pharmacogenet Genomics 22: 429-440.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 429-440
    • Binnington, J.M.1    Zhu, A.Z.2    Renner, C.C.3    Lanier, A.P.4    Hatsukami, D.K.5
  • 25
    • 0346998188 scopus 로고    scopus 로고
    • N-glucuronidation of trans-3′-hydroxycotinine by human liver microsomes
    • Kuehl GE, Murphy SE, (2003) N-glucuronidation of trans-3′-hydroxycotinine by human liver microsomes. Chem Res Toxicol 16: 1502-1506.
    • (2003) Chem Res Toxicol , vol.16 , pp. 1502-1506
    • Kuehl, G.E.1    Murphy, S.E.2
  • 26
    • 11144257101 scopus 로고    scopus 로고
    • Trans-3′-hydroxycotinine O- and N-glucuronidations in human liver microsomes
    • Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, et al. (2005) Trans-3′-hydroxycotinine O- and N-glucuronidations in human liver microsomes. Drug Metab Dispos 33: 23-30.
    • (2005) Drug Metab Dispos , vol.33 , pp. 23-30
    • Yamanaka, H.1    Nakajima, M.2    Katoh, M.3    Kanoh, A.4    Tamura, O.5
  • 27
    • 35148893148 scopus 로고    scopus 로고
    • Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism
    • Chen G, Blevins-Primeau AS, Dellinger RW, Muscat JE, Lazarus P, (2007) Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism. Cancer Res 67: 9024-9029.
    • (2007) Cancer Res , vol.67 , pp. 9024-9029
    • Chen, G.1    Blevins-Primeau, A.S.2    Dellinger, R.W.3    Muscat, J.E.4    Lazarus, P.5
  • 28
    • 73949104432 scopus 로고    scopus 로고
    • Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype
    • Berg JZ, Mason J, Boettcher AJ, Hatsukami DK, Murphy SE, (2010) Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype. J Pharmacol Exp Ther 332: 202-209.
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 202-209
    • Berg, J.Z.1    Mason, J.2    Boettcher, A.J.3    Hatsukami, D.K.4    Murphy, S.E.5
  • 30
    • 80052769963 scopus 로고    scopus 로고
    • Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure
    • Benowitz NL, Dains KM, Dempsey D, Wilson M, Jacob P, (2011) Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure. Nicotine Tob Res 13: 772-783.
    • (2011) Nicotine Tob Res , vol.13 , pp. 772-783
    • Benowitz, N.L.1    Dains, K.M.2    Dempsey, D.3    Wilson, M.4    Jacob, P.5
  • 31
    • 0027958225 scopus 로고
    • Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine
    • Benowitz NL, Jacob P 3rd, Fong I, Gupta S (1994) Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine. J Pharmacol Exp Ther 268: 296-303.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 296-303
    • Benowitz, N.L.1    Jacob 3rd, P.2    Fong, I.3    Gupta, S.4
  • 33
    • 67149146254 scopus 로고    scopus 로고
    • Genetic and environmental influences on the ratio of 3′hydroxycotinine to cotinine in plasma and urine
    • Swan GE, Lessov-Schlaggar CN, Bergen AW, He Y, Tyndale RF, et al. (2009) Genetic and environmental influences on the ratio of 3′hydroxycotinine to cotinine in plasma and urine. Pharmacogenet Genomics 19: 388-398.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 388-398
    • Swan, G.E.1    Lessov-Schlaggar, C.N.2    Bergen, A.W.3    He, Y.4    Tyndale, R.F.5
  • 35
    • 28144450359 scopus 로고    scopus 로고
    • CYP2A6 AND CYP2B6 are involved in nornicotine formation from nicotine in humans: interindividual differences in these contributions
    • Yamanaka H, Nakajima M, Fukami T, Sakai H, Nakamura A, et al. (2005) CYP2A6 AND CYP2B6 are involved in nornicotine formation from nicotine in humans: interindividual differences in these contributions. Drug Metab Dispos 33: 1811-1818.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1811-1818
    • Yamanaka, H.1    Nakajima, M.2    Fukami, T.3    Sakai, H.4    Nakamura, A.5
  • 36
    • 77951498164 scopus 로고    scopus 로고
    • Genetic Variation in Nicotine Metabolism Predicts the Efficacy of Extended-Duration Transdermal Nicotine Therapy
    • Lerman C, Jepson C, Wileyto EP, Patterson F, Schnoll R, et al. (2010) Genetic Variation in Nicotine Metabolism Predicts the Efficacy of Extended-Duration Transdermal Nicotine Therapy. Clin Pharmacol Ther 87: 553-557.
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 553-557
    • Lerman, C.1    Jepson, C.2    Wileyto, E.P.3    Patterson, F.4    Schnoll, R.5


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