Effect of nitric oxide on anterior segment physiology in monkeys

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 7, 2013, Pages 5103-5110

  Heyne, Galen W ^a   Kiland, Julie A ^a   Kaufman, Paul L ^a   Gabelt, B'Ann T ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Intraocular pressure; Nitric oxide; Outflow facility

Indexed keywords

N (G) NITROARGININE METHYL ESTER; N ACETYLPENICILLAMINE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTERIOR EYE SEGMENT; AQUEOUS HUMOR FORMATION; ARTICLE; CONTROLLED STUDY; EYE REFRACTION; FLUOROPHOTOMETRY; HAPLORHINI; HEART RATE; INTRAOCULAR PRESSURE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PUPIL;

EID: 84880947664     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-11491     Document Type: Article

References (43)

1. Wiederholt M, Sturm A, Lepple-Wienhues A. Relaxation of trabecular meshwork and ciliary muscle by release of nitric oxide. Invest Ophthalmol Vis Sci. 1994;35:2515-2520.
2. Gabelt BT, Kaufman PL, Rasmussen CA. Effect of nitric oxide compounds on monkey ciliary muscle in vitro. Exp Eye Res. 2011;93:321-327.
3. Selbach JM, Rohen JW, Steuhl KP, Lütjen-Drecoll E. Angioarchitecture and innervation of the primate anterior episclera. Curr Eye Res. 2005;30:337-344.
4. Becquet F, Courtois Y, Goureau O. Nitric oxide in the eye: multifaceted roles and diverse outcomes. Surv Ophthalmol. 1997;42:71-82.
5. Nathanson JA, McKee M. Alterations of ocular nitric oxide synthase in human glaucoma. Invest Ophthalmol Vis Sci. 1995;36:1774-1784.
6. Chen Z, Gu Q, Kaufman PL, Cynader MS. Histochemical mapping of NADPH-diaphorase in monkey and human eyes. Curr Eye Res. 1998;17:370-379.
7. Nathanson JA, McKee M. Identification of an extensive systemof nitric oxide-producing cells in the ciliary muscle and outflow pathway of the human eye. Invest Ophthalmol Vis Sci. 1995;36:1765-1773.
8. Krupin T, Weiss A, Becker B, Holmberg N, Fritz C. Increased intraocular pressure following topical azide or nitroprusside. Invest Ophthalmol Vis Sci. 1977;16:1002-1007.
9. Zamora DO, Keil JW. Episcleral venous pressure responses to topical nitroprusside and n-nitro-l-arginine methyl ester. Invest Ophthalmol Vis Sci. 2010;51:1614-1620.
10. Carreiro S, Anderson S, Gukasyan HJ, Krauss A, Prasanna G. Correlation of in vitro and in vivo kinetics of nitric oxide donors in ocular tissues. J Ocul Pharmacol Ther. 2009;25: 105-112.
11. Funk RH, Gehr J, Rohen JW. Short-term hemodynamic changes in episcleral arteriovenous anastomoses correlate with venous pressure and IOP changes in the albino rabbit. Curr Eye Res. 1996;15:87-93.
12. Schuman JS, Erickson K, Nathanson JA. Nitrovasodilator effects on intraocular pressure and outflow facility in monkeys. Exp Eye Res. 1994;58:99-105.
13. Wang R-F, Podos SM. Effect of the topical application of nitroglycerin on intraocular pressure in normal and glaucomatous monkeys. Exp Eye Res. 1995;60:337-339.
14. Larsson L-I, Maus TL, Brubaker RF, Nathanson JA. Topically applied hydralazine: effects on systemic cardiovascular parameters, blood-aqueous barrier, and aqueous humor dynamics in normotensive humans. J Ocul Pharmacol. 1995;11:145-156.
15. Stamer WD, Lei Y, Boussommier-Calleja A, Overby DR, Ethier CR. eNOS, a pressure-dependent regulator of intraocular pressure. Invest Ophthalmol Vis Sci. 2011;52:9438-9444.
16. Kaufman PL, Davis GE. "Minified" Goldmann applanating prism for tonometry in monkeys and humans. Arch Ophthalmol. 1980;98:542-546.
17. Croft MA, Kiland J, Gange SJ, Aref A, Pelzek CD, Kaufman PL. Comparison of Goldmann tonometry measurements using creamer vs fluorescein in cynomolgus monkeys. In: Lakshminarayanan V, ed. Basic and Clinical Applications of Vision Science. The Professor Jay M. Enoch Festschrift Volume, Documenta Ophthalmologica Proceedings Series, Vol 60. Dorderecht, The Netherlands: Kluwer; 1997:213-216.
18. Rasmussen CA, Gabelt BT, Kaufman PL. Aqueous humor dynamics in monkeys in response to the kappa opioid agonist bremazocine. Trans Am Ophthalmol Soc. 2007;105:225-239.
19. Bárány EH. Simultaneous measurement of changing intraocular pressure and outflow facility in the vervet monkey by constant pressure infusion. Invest Ophthalmol Vis Sci. 1964;3: 135-143.
20. Friedman LM, Furberg CD, DeMets DL. Sample size. In:Fundamentals of Clinical Trials. New York, NY: Springer; 2010:133-167.
21. Gabelt BT, Okka M, Dean RT, Kaufman PL. Aqueous humordynamics in monkeys after topical R-DOI. Invest Ophthalmol Vis Sci. 2005;46:4691-4694.
22. Gabelt BT, Robinson JC, Hubbard WC, et al. Apraclonidine and brimonidine effects of anterior ocular and cardiovascular physiology in normal and sympathectomized monkeys. Exp Eye Res. 1994;59:633-644.
23. Kaufman P, Erickson K, Bárány E. Effect of repeated anterior chamber perfusion on the intraocular pressure and total outflow facility in the cynomolgus monkey. Invest Ophthalmol Vis Sci. 1983;24:159-164.
24. Kamikawatoko S, Tokoro T, Ishida A, et al. Nitric oxide relaxes bovine ciliary muscle contracted by carbachol through elevation of cyclic GMP. Exp Eye Res. 1998;66:1-7.
25. Schneemann A, Dijkstra BG, van den Berg TJ, Kamphuis W, Hoyng PFJ. Nitric oxide/guanylate cyclase pathways and flow in anterior segment perfusion. Graefes Arch Clin Exp Ophthalmol. 2002;240:936-941.
26. Dismuke WM, Mbadugha CC, Ellis DZ. NO-induced regulation of human trabecular meshwork cell volume and aqueous humor outflow facility involve the BKCa ion channel. Am J Physiol Cell Physiol. 2008;294:C1378-C1386.
27. Shahidullah M, Yap M, To CH. Cyclic GMP, sodium nitroprus side and sodium azide reduce aqueous humour formation in the arterially perfused pig eye. Br J Pharmacol. 2005;145:84-92.
28. Kiel JW. Modulation of choroidal autoregulation in rabbits. ExpEye Res. 1999;69:413-429.
29. Kiel JW, Reitsamer HA, Walker JS, Kiel FW. Effects of nitric oxide synthase inhibition on ciliary blood flow, aqueous production and intraocular pressure. Exp Eye Res. 2001;73: 355-364.
30. Chuman H, Chuman T, Nao-i N, Sawada A. The effect of Larginine on intraocular pressure in the human eye. Curr Eye Res. 2000;20:511-516.
31. Garhöfer G, Resch H, Lung S, Weigert G, Schmetterer L.Intravenous administration of L-arginine increases retinal and choroidal blood flow. Am J Ophthalmol. 2005;140:69-76.
32. Oates JA, Brown NJ. Antihypertensive agents and the drug therapy of hypertension. In: Hardman JG, Limbird LE, eds. Goodman and Gilman's The Pharmacological Basis of Therapeutics. New York, NY: McGraw-Hill; 2001:871-900.
33. Fung H -L. Biochemical mechanism of nitroglycerin action and tolerance: is this old mystery solved? Ann Rev Pharmacol Toxicol. 2004;44:67-85.
34. Mohazzab-H KM,Kaminski PM,Agarwal R,Wolin MS. Potential role of a membrane-bound NADH oxidoreductase in nitric oxide release and arterial relaxation to nitroprusside. Circ Res. 1999;84:220-228.
35. Arnold WP, Longnecker DE, Epstein RM. Photodegradation of sodium nitroprusside: biological activity and cyanide release. Anesthesiology. 1984;61:254-260.
36. Burstein NL, Anderson JA. Corneal penetration and ocular bioavailability of drugs. J Ocul Pharmacol. 1985;1:309-326.
37. Bredt D, Snyder S. Nitric oxide: a physiologic messenger molecule. Ann Rev Biochem. 1994;63:175-195.
38. Beckman J, Koppenol W. Nitric oxide, superoxide, and peroxynitrite: the good, the bad and the ugly. Am J Physiol. 1996;271:C1424-C1437.
39. Van Haperen R, Cheng C, Mees BME, et al. Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice. Am J Pathol. 2003; 163:1677-1686.
40. Kaufman PL. Highlighted/invited editor's selection commentary on Stamer W, Lei Y: eNOS, a pressure-dependent regulator of intraocular pressure (Invest Ophthalmol Vis Sci. 2011;52: 9438-9444). Int Glauc Rev. 2012;13-4:1-3.
41. Buxton IL, Cheek DJ, Eckman D, Westfall DP, Sanders KM, Keef KD. NO-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists. Circ Res. 1993; 72:387-395.
42. Borghi V, Bastia E, Guzzetta M, et al. A novel nitric oxide releasing prostaglandin analog, NCX 125, reduces intraocular pressure in rabbit, dog, and primate models of glaucoma. J Ocul Pharmacol Ther. 2010;26:125-131.
43. Kaufman PL, Tian B, Gabelt BT, Liu X. Outflow enhancing drugs and gene therapy in glaucoma. In: Weinreb R, Krieglstein G, Kitazawa Y, eds. Glaucoma in the 21st Century. London, UK: Harcourt-Mosby; 2000:117-128.