A novel nitric oxide releasing prostaglandin analog, NCX 125, reduces intraocular pressure in rabbit, dog, and primate models of glaucoma

Journal of Ocular Pharmacology and Therapeutics

Volumn 26, Issue 2, 2010, Pages 125-131

  Borghi, Valentina ^a   Bastia, Elena ^a   Guzzetta, Massimiliano ^a   Chiroli, Valerio ^a   Toris, Carol B ^b   Batugo, Minerva R ^c   Carreiro, Samantha T ^c   Chong, Wesley K M ^c   Gale, David C ^c   Kucera, David J ^c   Jia, Liu ^c   Prasanna, Ganesh ^c,d   Ongini, Ennio ^a   Krauss, Achim H P ^c,e   Impagnatiello, Francesco ^a  

^a NicOx Research Institute   (United States)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^c Pfi Zer Global Research and Development La Jolla   (United States)

^d ALCON RESEARCH LTD   (United States)

^e GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (NITROOXYMETHYL) 2 (NITROOXY)ETHYL 7 [3,5 DIHYDROXY 2 (3 HYDROXY 5 PHENYLPENTYL)CYCLOPENTYL] 5 HEPTENOATE; LATANOPROST; NCX 125; PROSTAGLANDIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOG; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; GLAUCOMA; IN VITRO STUDY; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; MALE; NONHUMAN; PHEOCHROMOCYTOMA; PRIMATE; RABBIT; RAT;

EID: 77951672920     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2009.0120     Document Type: Article

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