Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway

Biomedicine and Pharmacotherapy

Volumn 67, Issue 6, 2013, Pages 481-487

  Ferreira, Adilson Kleber ^a,b   Meneguelo, Renato ^b   Pereira, Alexandre ^a   Filho, Otaviano Mendonça R ^c   Chierice, Gilberto Orivaldo ^b   Maria, Durvanei Augusto ^a,b  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF UBERABA   (Brazil)

Author keywords

Apoptosis; Caspase 3 like; MCF 7 breast cancer; Mitochondria; Synthetic phosphoethanolamine

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CYCLIN D1; CYTOCHROME C; PHOSPHOETHANOLAMINE; PROTEIN BCL 2; PROTEIN P53; REGULATOR PROTEIN; RHODAMINE; SYNTHETIC PHOSPHOETHANOLAMINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CELL CYCLE G1 PHASE; CELL DEATH; CELL POPULATION; CELL STRAIN MCF 7; CHROMATIN CONDENSATION; CONFOCAL MICROSCOPY; CYTOPLASM; DNA FRAGMENTATION; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASE-3-LIKE; MCF-7 BREAST CANCER; MITOCHONDRIA; SYNTHETIC PHOSPHOETHANOLAMINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL DEATH; CELL LINE, TUMOR; CYCLIN D1; CYTOCHROMES C; CYTOPLASM; DNA FRAGMENTATION; ETHANOLAMINES; FEMALE; G1 PHASE; HUMANS; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84880947374     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2013.01.012     Document Type: Article

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