Swept source optical coherence microscopy using a 1310 nm VCSEL light source

Optics Express

Volumn 21, Issue 15, 2013, Pages 18021-18033

  Ahsen, Osman O ^a   Tao, Yuankai K ^a   Potsaid, Benjamin M ^a,b   Sheikine, Yuri ^c   Jiang, James ^b   Grulkowski, Ireneusz ^a   Tsai, Tsung Han ^a   Jayaraman, Vijaysekhar ^d   Kraus, Martin F ^a,e   Connolly, James L ^c   Hornegger, Joachim ^e   Cable, Alex ^b   Fujimoto, James G ^a  

^a Department of Electrical Engineering and Computer Science   (United States)

^b THORLABS INC   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Praevium Research Inc   (United States)

^e UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LIGHT SOURCES; TISSUE;

ADJACENT OVERLAPPING; AXIAL RESOLUTIONS; MICROSCOPIC FIELDS; OPTICAL COHERENCE MICROSCOPY; SCANNING MICROSCOPE; TISSUE SPECIMENS; TRANSVERSE RESOLUTION; VERTICAL-CAVITY SURFACE EMITTING LASER;

MOEMS;

DEVICE FAILURE ANALYSIS; DEVICES; EQUIPMENT DESIGN; HUMAN; ILLUMINATION; IMAGE ENHANCEMENT; LASER; MICROSCOPY; OPTICAL COHERENCE TOMOGRAPHY; ARTICLE; EQUIPMENT; EQUIPMENT FAILURE;

EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; IMAGE ENHANCEMENT; LASERS; LIGHTING; MICROSCOPY; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84880945339     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.21.018021     Document Type: Article

References (36)

1. J. A. Izatt, M. R. Hee, G. M. Owen, E. A. Swanson, and J. G. Fujimoto, "Optical coherence microscopy in scattering media," Opt. Lett. 19(8), 590-592 (1994).
2. A. D. Aguirre, P. Hsiung, T. H. Ko, I. Hartl, and J. G. Fujimoto, "High-resolution optical coherence microscopy for high-speed, in vivo cellular imaging," Opt. Lett. 28(21), 2064-2066 (2003).
3. A. D. Aguirre, Y. Chen, B. Bryan, H. Mashimo, Q. Huang, J. L. Connolly, and J. G. Fujimoto, "Cellular resolution ex vivo imaging of gastrointestinal tissues with optical coherence microscopy," J. Biomed. Opt. 15(1), 016025 (2010).
4. C. Zhou, D. W. Cohen, Y. Wang, H.-C. Lee, A. E. Mondelblatt, T.-H. Tsai, A. D. Aguirre, J. G. Fujimoto, and J. L. Connolly, "Integrated optical coherence tomography and microscopy for ex vivo multiscale evaluation of human breast tissues," Cancer Res. 70(24), 10071-10079 (2010).
5. C. Zhou, Y. Wang, A. D. Aguirre, T. H. Tsai, D. W. Cohen, J. L. Connolly, and J. G. Fujimoto, "Ex vivo imaging of human thyroid pathology using integrated optical coherence tomography and optical coherence microscopy," J. Biomed. Opt. 15(1), 016001 (2010).
6. H. C. Lee, C. Zhou, D. W. Cohen, A. E. Mondelblatt, Y. Wang, A. D. Aguirre, D. Shen, Y. Sheikine, J. G. Fujimoto, and J. L. Connolly, "Integrated optical coherence tomography and optical coherence microscopy imaging of ex vivo human renal tissues," J. Urol. 187(2), 691-699 (2012).
7. K. Kayser, E. Anyanwu, H. G. Bauer, and I. Vogt-Moykopf, "Tumor Presence at Resection Boundaries and Lymph-Node Metastasis in Bronchial Carcinoma Patients," Thorac. Cardiovasc. Surg. 41(5), 308-311 (1993).
8. F. J. Fleming, A. D. K. Hill, E. W. Mc Dermott, A. O'Doherty, N. J. O'Higgins, and C. M. Quinn, "Intraoperative margin assessment and re-excision rate in breast conserving surgery," Eur. J. Surg. Oncol. 30(3), 233-237 (2004).
9. A. Binahmed, R. W. Nason, and A. A. Abdoh, "The clinical significance of the positive surgical margin in oral cancer," Oral Oncol. 43(8), 780-784 (2007).
10. J. W. Hettinger, M. de la Peña Mattozzi, W. R. Myers, M. E. Williams, A. Reeves, R. L. Parsons, R. C. Haskell, D. C. Petersen, R. Wang, and J. I. Medford, "Optical coherence microscopy. a technology for rapid, in vivo, nondestructive visualization of plants and plant cells," Plant Physiol. 123(1), 3-16 (2000).
11. B. M. Hoeling, A. D. Fernandez, R. C. Haskell, E. Huang, W. R. Myers, D. C. Petersen, S. E. Ungersma, R. Y. Wang, M. E. Williams, and S. E. Fraser, "An optical coherence microscope for 3-dimensional imaging in developmental biology," Opt. Express 6(7), 136-146 (2000).
12. M. A. Choma, A. K. Ellerbee, S. Yazdanfar, and J. A. Izatt, "Doppler flow imaging of cytoplasmic streaming using spectral domain phase microscopy," J. Biomed. Opt. 11(2), 024014 (2006).
13. C. Vinegoni, T. Ralston, W. Tan, W. Luo, D. L. Marks, and S. A. Boppart, "Integrated structural and functional optical imaging combining spectral-domain optical coherence and multiphoton microscopy," Appl. Phys. Lett. 88(5), 053901 (2006).
14. V. J. Srinivasan, H. Radhakrishnan, J. Y. Jiang, S. Barry, and A. E. Cable, "Optical coherence microscopy for deep tissue imaging of the cerebral cortex with intrinsic contrast," Opt. Express 20(3), 2220-2239 (2012).
15. S. Tang, T. B. Krasieva, Z. Chen, and B. J. Tromberg, "Combined multiphoton microscopy and optical coherence tomography using a 12-fs broadband source," J. Biomed. Opt. 11(2), 020502 (2006).
16. S. W. Huang, A. D. Aguirre, R. A. Huber, D. C. Adler, and J. G. Fujimoto, "Swept source optical coherence microscopy using a Fourier domain mode-locked laser," Opt. Express 15(10), 6210-6217 (2007).
17. B. W. Graf, S. G. Adie, and S. A. Boppart, "Correction of coherence gate curvature in high numerical aperture optical coherence imaging," Opt. Lett. 35(18), 3120-3122 (2010).
18. B. W. Graf and S. A. Boppart, "Multimodal In Vivo Skin Imaging with Integrated Optical Coherence and Multiphoton Microscopy," IEEE J. Sel. Top. Quantum Electron. 18(4), 1280-1286 (2012).
19. A. Wax, C. H. Yang, and J. A. Izatt, "Fourier-domain low-coherence interferometry for light-scattering spectroscopy," Opt. Lett. 28(14), 1230-1232 (2003).
20. C. Y. Xu, C. Vinegoni, T. S. Ralston, W. Luo, W. Tan, and S. A. Boppart, "Spectroscopic spectral-domain optical coherence microscopy," Opt. Lett. 31(8), 1079-1081 (2006).
21. S. Tang, C. H. Sun, T. B. Krasieva, Z. Chen, and B. J. Tromberg, "Imaging subcellular scattering contrast by using combined optical coherence and multiphoton microscopy," Opt. Lett. 32(5), 503-505 (2007).
22. B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, "Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging," Nat. Med. 15(10), 1219-1223 (2009).
23. G. Liu, W. Jia, V. Sun, B. Choi, and Z. Chen, "High-resolution imaging of microvasculature in human skin invivo with optical coherence tomography," Opt. Express 20(7), 7694-7705 (2012).
24. T. S. Ralston, D. L. Marks, P. S. Carney, and S. A. Boppart, "Interferometric synthetic aperture microscopy," Nat. Phys. 3(2), 129-134 (2007).
25. V. Jayaraman, J. Jiang, H. Li, P. Heim, G. Cole, B. Potsaid, J. G. Fujimoto, and A. Cable, "OCT imaging up to 760kHz axial scan rate using single-mode 1310nm MEMS-tunable VCSELs with> 100nm tuning range," in CLEO: Science and Innovations (Optical Society of America, 2011).
26. V. Jayaraman, J. Jiang, B. Potsaid, G. Cole, J. Fujimoto, and A. Cable, "Design and performance of broadly tunable, narrow line-width, high repetition rate 1310nm VCSELs for swept source optical coherence tomography," in Proc. of SPIE Vol, 2012), 82760D-82761.
27. B. Potsaid, V. Jayaraman, J. G. Fujimoto, J. Jiang, P. J. S. Heim, and A. E. Cable, "MEMS tunable VCSEL light source for ultrahigh speed 60kHz-1MHz axial scan rate and long range centimeter class OCT imaging," in SPIE BiOS, (International Society for Optics and Photonics, 2012), 82130M-82130M-82138.
28. J. F. Xi, L. Huo, J. S. Li, and X. D. Li, "Generic real-time uniform K-space sampling method for high-speed swept-Source optical coherence tomography," Opt. Express 18(9), 9511-9517 (2010).
29. M. Rajadhyaksha, R. R. Anderson, and R. H. Webb, "Video-rate confocal scanning laser microscope for imaging human tissues in vivo," Appl. Opt. 38(10), 2105-2115 (1999).
30. M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahighresolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Opt. Express 12(11), 2404-2422 (2004).
31. A. D. Aguirre, "Advances in Optical Coherence Tomography and Microscopy for endoscopic applications and functional neuroimaging," Ph D (Harvard-MIT Division of Health Sciences and Technology, 2008).
32. R. Szeliski, "Image alignment and stitching: A tutorial," Found. Trends. Comput. Graph. Vis. 2(1), 1-104 (2006).
33. A. Agarwala, M. Dontcheva, M. Agrawala, S. Drucker, A. Colburn, B. Curless, D. Salesin, and M. Cohen, "Interactive digital photomontage," ACM Trans. Graphic 23(3), 294-302 (2004).
34. S. Winder, G. Hua, and M. Brown, "Picking the best DAISY," in IEEE Conference on Computer Vision and Pattern Recognition, 2009, pp. 178-185.
35. R. A. Drezek, T. Collier, C. K. Brookner, A. Malpica, R. Lotan, R. R. Richards-Kortum, and M. Follen, "Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid," Am. J. Obstet. Gynecol. 182(5), 1135-1139 (2000).
36. S. Abeytunge, Y. Li, B. Larson, R. Toledo-Crow, and M. Rajadhyaksha, "Rapid confocal imaging of large areas of excised tissue with strip mosaicing," J. Biomed. Opt. 16(5), 050504 (2011).