Human subcutaneous adipose tissue Glut 4 mRNA expression in obesity and type 2 diabetes

Acta Diabetologica

Volumn 50, Issue 2, 2013, Pages 227-232

  Kouidhi, Soumaya ^a   Berrhouma, Rym ^a   Rouissi, Kamel ^a   Jarboui, Slim ^c   Clerget Froidevaux, Marie Stéphanie ^b   Seugnet, Isabelle ^b   Bchir, Fattouma ^d   Demeneix, Barbara ^b   Guissouma, Hajer ^a   Elgaaied, Amel Benammar ^a  

^a UNIVERSITY OF TUNIS EL MANAR   (Tunisia)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c CHARLES NICOLLE HOSPITAL   (Tunisia)

^d PASTEUR INSTITUTE OF TUNIS   (Tunisia)

Author keywords

Adipose tissue; GLUT4; Insulin resistance; Obesity; Type 2 diabetes

Indexed keywords

GLUCOSE TRANSPORTER 4;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIABETIC OBESITY; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GLUT4 GENE; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; MALE; MARKER GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUBCUTANEOUS FAT; WAIST CIRCUMFERENCE;

BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; FEMALE; GENE EXPRESSION; GLUCOSE TRANSPORTER TYPE 4; HUMANS; INSULIN RESISTANCE; LINEAR MODELS; MALE; MIDDLE AGED; OBESITY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBCUTANEOUS FAT;

EID: 84880920739     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-011-0295-8     Document Type: Article

References (29)

1. Goossens GH (2008) The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance. Physiol Behav 94:206-218
2. Matsuzawa Y (2008) The role of fat topology in the risk of disease. Int J Obes (Lond) 32(Suppl 7):S83-S92
3. Hamdy O, Porramatikul S, Al-Ozairi E (2006) Metabolic obesity: the paradox between visceral and subcutaneous fat. Curr Diabetes Rev 2:367-373
4. Murdolo G, Smith U (2006) The dysregulated adipose tissue: a connecting link between insulin resistance, type 2 diabetes mellitus and atherosclerosis. Nutr Metab Cardiovasc Dis 16(Suppl 1):S35-S38
5. Im SS, Kwon SK, Kim TH, Kim HI, Ahn YH (2007) Regulation of glucose transporter type 4 isoform gene expression in muscle and adipocytes. IUBMB Life 59:134-145
6. Kahn BB, Cushman SW, Flier JS (1989) Regulation of glucose transporter-specific mRNA levels in rat adipose cells with fasting and refeeding. Implications for in vivo control of glucose transporter number. J Clin Invest 83:199-204
7. Cushman SW, Wardzala LJ (1980) Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane. J Biol Chem 255:4758-4762
8. Huang S, Czech MP (2007) The GLUT4 glucose transporter. Cell Metab 5:237-252
9. Karnieli E, Armoni M (2008) Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: from physiology to pathology. Am J Physiol Endocrinol Metab 295:E38-E45
10. McGowan KM, Long SD, Pekala PH (1995) Glucose transporter gene expression: regulation of transcription and mRNA stability. Pharmacol Ther 66:465-505
11. Bryant NJ, Govers R, James DE (2002) Regulated transport of the glucose transporter GLUT4. Nat Rev Mol Cell Biol 3:267-277
12. Armoni M, Harel C, EK (2005) GLUT4 goes abnormal: regulation of the insulin-responsive GLUT4 transporter in abnormal metabolic states. Curr Med Chem Immunol Endocr Metab Agents 5: 207-218
13. Garvey WT, Maianu L, Hancock JA, Golichowski AM, Baron A (1992) Gene expression of GLUT4 in skeletal muscle from insulin-resistant patients with obesity, IGT, GDM, and NIDDM. Diabetes 41:465-475
14. Veilleux A, Blouin K, Rheaume C, Daris M, Marette A, Tchernof A (2009) Glucose transporter 4 and insulin receptor substrate-1 messenger RNA expression in omental and subcutaneous adipose tissue in women. Metabolism 58:624-631
15. Marita AR, Sarkar JA, Rane S (2005) Type 2 diabetes in non-obese Indian subjects is associated with reduced leptin levels: study from Mumbai, Western India. Mol Cell Biochem 275:143-151
16. Schuster DP (2009) Changes in physiology with increasing fat mass. Semin Pediatr Surg 18:126-135
17. Zhu XY, Zhang XZ, Xu L, Zhong XY, Ding Q, Chen YX (2009) Transplantation of adipose-derived stem cells overexpressing hHGF into cardiac tissue. Biochem Biophys Res Commun 379:1084-1090
18. Ducluzeau PH, Perretti N, Laville M, Andreelli F, Vega N, Riou JP, Vidal H (2001) Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes 50:1134-1142
19. Wozniak SE, Gee LL, Wachtel MS, Frezza EE (2009) Adipose tissue: the new endocrine organ? A review article. Dig Dis Sci 54:1847-1856
20. Galic S, Oakhill JS, Steinberg GR (2010) Adipose tissue as an endocrine organ. Mol Cell Endocrinol 316:129-139
21. Gnacinska M, Malgorzewicz S, Stojek M, Lysiak-Szydlowska W, Sworczak K (2009) Role of adipokines in complications related to obesity: a review. Adv Med Sci 54:150-157
22. Sivitz WI, DeSautel SL, Kayano T, Bell GI, Pessin JE (1989) Regulation of glucose transporter messenger RNA in insulin-deficient states. Nature 340:72-74
23. Brunetti A, Brunetti L, Foti D, Accili D, Goldfine ID (1996) Human diabetes associated with defects in nuclear regulatory proteins for the insulin receptor gene. J Clin Invest 97:258-262
24. Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, Soos MA, Maslen GL, Williams TD, Lewis H, Schafer AJ, Chatterjee VK, O'Rahilly S (1999) Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402:880-883
25. Berger J, Biswas C, Vicario PP, Strout HV, Saperstein R, Pilch PF (1989) Decreased expression of the insulin-responsive glucose transporter in diabetes and fasting. Nature 340:70-72
26. Olson AL, Pessin JE (1995) Transcriptional regulation of the human GLUT4 gene promoter in diabetic transgenic mice. J Biol Chem 270:23491-23495
27. Li J, Houseknecht KL, Stenbit AE, Katz EB, Charron MJ (2000) Reduced glucose uptake precedes insulin signaling defects in adipocytes from heterozygous GLUT4 knockout mice. FASEB J 14:1117-1125
28. Stenbit AE, Tsao TS, Li J, Burcelin R, Geenen DL, Factor SM, Houseknecht K, Katz EB, Charron MJ (1997) GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes. Nat Med 3:1096-1101
29. Gerrits PM, Olson AL, Pessin JE (1993) Regulation of the GLUT4/muscle-fat glucose transporter mRNA in adipose tissue of insulin-deficient diabetic rats. J Biol Chem 268:640-644