Acute normovolemic hemodilution in the pig is associated with renal tissue edema, impaired renal microvascular oxygenation, and functional loss

Anesthesiology

Volumn 119, Issue 2, 2013, Pages 256-269

  Konrad, Franziska M ^a,b   Mik, Egbert G ^b   Bodmer, Sander I A ^b   Ates, N Bahar ^b   Willems, Henriëtte F E M ^b   Klingel, Karin ^a   De Geus, Hilde R H ^b   Stolker, Robert Jan ^b   Johannes, Tanja ^b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTALLOID; EDEMA; FEMALE; HEMATOCRIT; HEMODILUTION; HEMODYNAMICS; HISTOPATHOLOGY; KIDNEY CORTEX; KIDNEY DISTAL TUBULE; KIDNEY FUNCTION; KIDNEY MEDULLA; NONHUMAN; OXYGEN CONSUMPTION; PLASMA OSMOLALITY; PRIORITY JOURNAL; SWINE; TISSUE OXYGENATION;

ANIMALS; DISEASE MODELS, ANIMAL; EDEMA; FEMALE; HEMODILUTION; HEMODYNAMICS; HYDROXYETHYL STARCH DERIVATIVES; ISOTONIC SOLUTIONS; KIDNEY; KIDNEY DISEASES; MICROVESSELS; OXYGEN; OXYGEN CONSUMPTION; PLASMA SUBSTITUTES; SWINE;

EID: 84880904620     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e31829bd9bc     Document Type: Article

References (53)

1. Beards SC, Watt T, Edwards JD, Nightingale P, Farragher EB: Comparison of the hemodynamic and oxygen transport responses to modifed fuid gelatin and hetastarch in critically ill patients: A prospective, randomized trial. Crit Care Med 1994; 22:600-5 (Pubitemid 24121560)
2. Jones SB, Whitten CW, Monk TG: Infuence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. J Clin Anesth 2004; 16:11-7 (Pubitemid 38251469)
3. Licker M, Ellenberger C, Sierra J, Kalangos A, Diaper J, Morel D: Cardioprotective effects of acute normovolemic hemodilu-tion in patients undergoing coronary artery bypass surgery. Chest 2005; 128:838-47 (Pubitemid 41149092)
4. Habib RH, Zacharias A, Schwann TA, Riordan CJ, Engoren M, Durham SJ, Shah A: Role of hemodilutional anemia and transfusion during cardiopulmonary bypass in renal injury after coronary revascularization: Implications on operative outcome. Crit Care Med 2005; 33:1749-56 (Pubitemid 41153700)
5. Karkouti K, Beattie WS, Wijeysundera DN, Rao V, Chan C, Dattilo KM, Djaiani G, Ivanov J, Karski J, David TE: Hemodilution during cardiopulmonary bypass is an independent risk factor for acute renal failure in Adult cardiac surgery. J Thorac Cardiovasc Surg 2005; 129:391-400 (Pubitemid 40169564)
6. Rosenberger C, Rosen S, Heyman SN: Renal parenchymal oxygenation and hypoxia adaptation in acute kidney injury. Clin Exp Pharmacol Physiol 2006; 33:980-8 (Pubitemid 44427322)
7. 2 during acute normo-volemic hemodilution. Am J Physiol Renal Physiol 2007; 292:F796-3 (Pubitemid 46220548)
8. Fine LG, Orphanides C, Norman JT: Progressive renal disease: The chronic hypoxia hypothesis. Kidney Int Suppl 1998; 65:S74-8 (Pubitemid 28204569)
9. Kang DH, Kanellis J, Hugo C, Truong L, Anderson S, Kerjaschki D, Schreiner GF, Johnson RJ: Role of the micro-vascular endothelium in progressive renal disease. J Am Soc Nephrol 2002; 13:806-16 (Pubitemid 34183950)
10. Nangaku M, Eckardt KU: Hypoxia and the HIF system in kidney disease. J Mol Med (Berl) 2007; 85:1325-30 (Pubitemid 50004091)
11. Higgins DF, Kimura K, Bernhardt WM, Shrimanker N, Akai Y, Hohenstein B, Saito Y, Johnson RS, Kretzler M, Cohen CD, Eckardt KU, Iwano M, Haase VH: Hypoxia promotes fbro-genesis in vivo via HIF-1 stimulation of epithelial-to-mesen-chymal transition. J Clin Invest 2007; 117:3810-20 (Pubitemid 350224091)
12. Swindle MM, Makin A, Herron AJ, Clubb FJ JR, Frazier KS: Swine as models in biomedical research and toxicology testing. Vet Pathol 2012; 49:344-56
13. Mik EG, Van Leeuwen TG, Raat NJ, Ince C: Quantitative determination of localized tissue oxygen concentration in vivo by two-photon excitation phosphorescence lifetime measurements. J Appl Physiol 2004; 97:1962-9 (Pubitemid 39426017)
14. Schwarte LA, Fournell A, Van Bommel J, Ince C: Redistribution of intestinal microcirculatory oxygenation during acute hemodilution in pigs. J Appl Physiol 2005; 98:1070-5 (Pubitemid 40283691)
15. Vanderkooi JM, Wilson DF: A new method for measuring oxygen concentration in biological systems. Adv Exp Med Biol 1986; 200:189-93
16. Harms FA, De Boon WM, Balestra GM, Bodmer SI, Johannes T, Stolker RJ, Mik EG: Oxygen-dependent delayed fuores-cence measured in skin after topical application of 5-ami-nolevulinic acid. J Biophotonics 2011; 4:731-9
17. Pedersen KR, Ravn HB, Hjortdal VE, Nørregaard R, Povlsen JV: Neutrophil gelatinase-associated lipocalin (NGAL): Validation of commercially available ELISA. Scand J Clin Lab Invest 2010; 70:374-82
18. Ranucci M, Romitti F, Isgrò G, Cotza M, Brozzi S, Boncilli A, Ditta A: Oxygen delivery during cardiopulmonary bypass and acute renal failure after coronary operations. Ann Thorac Surg 2005; 80:2213-20 (Pubitemid 41718057)
19. Niemi TT, Miyashita R, Yamakage M: Colloid solutions: A clinical update. J Anesth 2010; 24:913-25
20. Wilcox CS: Regulation of renal blood fow by plasma chloride. J Clin Invest 1983; 71:726-35 (Pubitemid 13160821)
21. Zuurbier CJ, Van Iterson M, Ince C: Functional heterogeneity of oxygen supply-consumption ratio in the heart. Cardiovasc Res 1999; 44:488-97 (Pubitemid 30012051)
22. Boura C, Caron A, Longrois D, Mertes PM, Labrude P, Menu P: Volume expansion with modifed hemoglobin solution, colloids, or crystalloid after hemorrhagic shock in rabbits: Effects in skeletal muscle oxygen pressure and use versus arterial blood velocity and resistance. Shock 2003; 19:176-82
23. Friedman Z, Berkenstadt H, Preisman S, Perel A: A comparison of lactated ringer's solution to hydroxyethyl starch 6% in a model of severe hemorrhagic shock and continuous bleeding in dogs. Anesth Analg 2003; 96:39-5 (Pubitemid 36042029)
24. Kellum JA: Fluid resuscitation and hyperchloremic acidosis in experimental sepsis: Improved short-term survival and acid-base balance with Hextend compared with saline. Crit Care Med 2002; 30:300-5 (Pubitemid 34158110)
25. Gottschalk A, Standl TG, Freitag M, Radtke P, Rempf C, Burmeister MA, Horn E P, Strate T, Schulte am Esch J: Effects of isovolaemic haemodilution on oxygenation of liver and skeletal muscle. Eur J Anaesthesiol 2005; 22:181-8 (Pubitemid 40694731)
26. Hutter J, Habler O, Kleen M, Tiede M, Podtschaske A, Kemming G, Corso C, Batra S, Keipert P, Faithfull S, Messmer K: Effect of acute normovolemic hemodilution on distribution of blood fow and tissue oxygenation in dog skeletal muscle. J Appl Physiol 1999; 86:860-6 (Pubitemid 29118005)
27. Standl T, Burmeister MA, Schroeder F, Currlin E, Schulte am Esch J, Freitag M, Schulte am Esch J: Hydroxyethyl starch (HES) 130/0.4 provides larger and faster increases in tissue oxygen tension in comparison with prehemodilution values than HES 70/0.5 or HES 200/0.5 in volunteers undergoing acute normo-volemic hemodilution. Anesth Analg 2003; 96:936-43 (Pubitemid 36359019)
28. Schramm S, Wettstein R, Wessendorf R, Jakob SM, Banic A, Erni D: Acute normovolemic hemodilution improves oxygenation in ischemic fap tissue. ANESTHESIOLOGY 2002; 96:1478-84 (Pubitemid 34587219)
29. 2 and perfusion in the rabbit kidney in vivo. Adv Exp Med Biol 2007; 599:93-9
30. Mathru M, Kleinman B, Blakeman B, Dries D, Zecca A, Rao T: Cardiovascular adjustments and gas exchange during extreme hemodilution in humans. Crit Care Med 1991; 19:700-4
31. Migdal S, Alexander EA, Bruns FJ, Riley AL, Levinsky NG: Effect of hemodilution on the distribution of renal blood fow. Circ Res 1975; 36:71-5
32. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-77
33. Varpula M, Karlsson S, Parviainen I, Ruokonen E, Pettilä V; Finnsepsis Study Group: Community-acquired septic shock: Early management and outcome in a nationwide study in Finland. Acta Anaesthesiol Scand 2007; 51:1320-6 (Pubitemid 47609501)
34. Venn R, Steele A, Richardson P, Poloniecki J, Grounds M, Newman P: Randomized controlled trial to investigate infu-ence of the fuid challenge on duration of hospital stay and perioperative morbidity in patients with hip fractures. Br J Anaesth 2002; 88:65-1 (Pubitemid 34048564)
35. Prien T, Backhaus N, Pelster F, Pircher W, Bünte H, Lawin P: Effect of intraoperative fuid administration and colloid osmotic pressure on the formation of intestinal edema during gastrointestinal surgery. J Clin Anesth 1990; 2:317-23 (Pubitemid 20326173)
36. Rizoli SB: Crystalloids and colloids in trauma resuscitation: A brief overview of the current debate. J Trauma 2003; 54(5 suppl):S82-8 (Pubitemid 36758856)
37. Marty AT, Miyamoto AM, Weil MH, Philips PA: Oncotic normalization after dilutional bypass and hypothermia. Arch Surg 1974; 109:61-4
38. Sanchez de Léon R, Paterson JL, Sykes MK: Changes in colloid osmotic pressure with plasma albumin concentration associated with extracorporeal circulation. Br J Anaesth 1982; 54:465-73 (Pubitemid 12143833)
39. Cabrales P, Tsai AG: Plasma viscosity regulates systemic and microvascular perfusion during acute extreme anemic conditions. Am J Physiol Heart Circ Physiol 2006; 291:H2445-52
40. Haynes GR, Navickis RJ, Wilkes MM: Albumin administra-tion-What is the evidence of clinical beneft? A systematic review of randomized controlled trials. Eur J Anaesthesiol 2003; 20:771-93 (Pubitemid 37236932)
41. Linko K, Mäkeläinen A: Hydroxyethyl starch 120, dextran 70 and acetated Ringer's solution: Hemodilution, albumin, colloid osmotic pressure and fuid balance following replacement of blood loss in pigs. Acta Anaesthesiol Scand 1988; 32:228-33
42. Utley JR, Wachtel C, Cain RB, Spaw EA, Collins JC, Stephens DB: Effects of hypothermia, hemodilution, and pump oxygen-ation on organ water content, blood fow and oxygen delivery, and renal function. Ann Thorac Surg 1981; 31:121-33 (Pubitemid 11173185)
43. Kamei K, Ito S, Iijima K: [Constant-infusion technique of inu-lin clearance without urine collection]. Nihon Jinzo Gakkai Shi 2011; 53:181-8
44. Habler O, Kleen M, Hutter J, Podtschaske A, Tiede M, Kemming G, Corso C, Batra S, Keipert P, Faithfull S, Messmer K: Effects of hemodilution on splanchnic perfusion and hep-atorenal function. II. Renal perfusion and hepatorenal function. Eur J Med Res 1997; 2:419-24
45. Rosenberger C, Mandriota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU: Expression of hypoxia-inducible factor-1alpha and-2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 2002; 13:1721-32 (Pubitemid 34700596)
46. De Geus HR, Bakker J, Lesaffre EM, Le Noble JL: Neutrophil gelatinase-associated lipocalin at ICU admission predicts for acute kidney injury in adult patients. Am J Respir Crit Care Med 2011; 183:907-14
47. Perel P, Roberts I: Colloids versus crystalloids for fuid resuscitation in critically ill patients. Cochrane Database Syst Rev 2011; CD000567
48. Dart AB, Mutter TC, Ruth CA, Taback SP: Hydroxyethyl starch (HES) versus other fluid therapies: Effects on kidney function. Cochrane Database Syst Rev 2010; CD007594
49. Thomas G, Balk EM, Jaber BL: Effect of intensive insulin therapy and pentastarch resuscitation on acute kidney injury in severe sepsis. Am J Kidney Dis 2008; 52:13-7 (Pubitemid 351853275)
50. Lehmann GB, Asskali F, Boll M, Burmeister MA, Marx G, Hilgers R, Förster H: HES 130/0.42 shows less alteration of pharmacokinetics than HES 200/0.5 when dosed repeatedly. Br J Anaesth 2007; 98:635-44 (Pubitemid 47078670)
51. Sirtl C, Laubenthal H, Zumtobel V, Kraft D, Jurecka W: Tissue deposits of hydroxyethyl starch (HES): Dose-dependent and time-related. Br J Anaesth 1999; 82:510-5 (Pubitemid 29151229)
52. Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, Moerer O, Gruendling M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffer M, Reinhart K; German Competence Network Sepsis (SepNet): Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008; 358:125-39
53. Jungheinrich C, Neff TA: Pharmacokinetics of hydroxyethyl starch. Clin Pharmacokinet 2005; 44:681-99 (Pubitemid 40994079)