Effects of isovolaemic haemodilution on oxygenation of liver and skeletal muscle

European Journal of Anaesthesiology

Volumn 22, Issue 3, 2005, Pages 181-188

  Gottschalk, André ^a   Standl, T G ^a   Freitag, M ^a   Radtke, P ^a   Rempf, C ^a   Burmeister, M A ^a   Horn, E P ^a   Strate, T ^a   Schulte Am Esch, J ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Anaesthesia, thiopental, fentanyl, vecuronium, midazolam; Haemodilution, hydroxyethyl starch, saline; Oxygen Consumption, liver, skeletal muscle

Indexed keywords

FENTANYL DERIVATIVE; HETASTARCH; MIDAZOLAM; OXYGEN; RINGER LACTATE SOLUTION; THIOPENTAL; VECURONIUM;

ANESTHESIOLOGICAL TECHNIQUES; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DOG; ELECTRODE; FEMALE; HEMODILUTION; HEMODYNAMICS; LIVER; MALE; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN CONSUMPTION; OXYGEN TISSUE LEVEL; OXYGEN TRANSPORT; PARAMETER; POLAROGRAPHY; RANDOMIZATION; SKELETAL MUSCLE; SPLENECTOMY; TISSUE OXYGENATION; TONOMETER;

ANESTHETICS, INTRAVENOUS; ANIMALS; BLOOD PRESSURE; CARDIAC OUTPUT; CENTRAL VENOUS PRESSURE; DOGS; FEMALE; HEMATOCRIT; HEMODILUTION; HETASTARCH; ISOTONIC SOLUTIONS; LIVER; MALE; MODELS, ANIMAL; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; PLASMA SUBSTITUTES; RANDOM ALLOCATION; RESPIRATION, ARTIFICIAL; SPLENECTOMY; TIME FACTORS; VASCULAR RESISTANCE;

EID: 18844450521     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0265021505000323     Document Type: Article

References (15)

1. Freyburger G, Dubreuil M, Boisseau MR, Janvier G. Rheological properties of commonly used plasma substitutes during preoperative normovolemic acute haemodilution. Br J Anesth 1996; 76: 519-525.
2. Kreimeier U, Messmer K. Haemodilution in clinical surgery: state of the art 1996. World J Surg 1996; 20: 1208-1217.
3. Doss DN, Estafanous FG, Ferrario CM, et al. Mechanism of systemic vasodilation during normovolemic haemodilution. Anesth Analg 1995; 81: 30-34.
4. Holbeck S, Grande PO. Effects on capillary fluid permaebility and fluid exchange of albumin, dextran, gelatin and hydroxyethylstarch in cat skeletal muscle. Crit Care Med 2000; 28: 1089-1095.
5. Standl T, Burmeister MA, Schroeder F, et al. Hydroxyethyl starch (HES) 130/0.4 provides larger and faster tissue oxygen tension in comparison with prehaemodilution values than HES 70/0.5 or HES 200/0.5 in volunteers undergoing acute normovolemic haemodilution. Anesth Analg 2003; 96: 936-943.
6. Freitag M, Standl T, Horn EP, Wilhelm S, Schulte am Esch J. Acute normovolemic haemodilution beyond a haematocrit of 25%: ratio of skeletal muscle tissue oxygen tension and cardiac index is not maintained in the healthy dog. Eur J Anaesthesiol 2002; 19: 487-494.
7. Van Bommel J, Trouwborst A, Schwarte L, Siegeund M, Ince C, Henny CP. Intestinal and cerebral oxygenation during severe isovolemic haemodilution and subsequent hyperoxic ventilation in a pig model. Anesthesiology 2002; 97: 660-670.
8. Van der Linden P, Schwartz D, De Groote F, et al. Critical haemoglobin concentrations in anaesthetized dogs: comparison of two plasma substitutes. Br J Anaesth 1998; 81: 556-562.
9. Van Woerkens ECSM, Trouwborst A, Duncker DJGM, Koning MMG, Boosma F, Verdouw PD. Catecholamines and regional hemodynamics during isovolemic haemodilution in anesthetized pigs. J Appl Physiol 1992; 72: 760-769.
10. Nöldge GF, Priebe HJ, Bohle W, Buttler KJ, Geiger K. Effects of acute normovolemic haemodilution on splanchnic oxygenation and on hepatic histology and metabolism in anesthetized pigs. Anesthesiology 1991; 74: 908-918.
11. Knudson MM, Bermudez KM, Doyle C, Mackersie RC, Hopf HW, Morabito D. Use of tissue oxygen tension measurement during resuscitation from shock. J Trauma 1997; 43: 614-616.
12. Lee SK, Morabito D, Hemphill JC, et al. Small volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out of hospital model of hemorrhage in swine. Acad Emerg Med 2002; 9: 969-976.
13. Messmer KF. Acceptable haematocrit levels in surgical patients. World J Surg 1987; 11: 41-46.
14. Zander R. Optimal haematocrit 30%: farewell to a fallacy. Infusion Therapy 1999; 26: 186-190.
15. Standl T, Horn EP, Wilhelm S, et al. Bovine haemoglobin is more potent than autologous red blood cells in restoring muscular tissue oxygen oxygenation after profound isovolaemic haemodilution in dogs. Can J Anesth 1996; 43: 714-723.