Microscopic matrix remodeling precedes endothelial morphological changes during capillary morphogenesis

Journal of Biomechanical Engineering

Volumn 135, Issue 7, 2013, Pages

  McLeod, Claire ^a,b   Higgins, John ^a   Miroshnikova, Yekaterina ^a,c   Liu, Rachel ^a,b   Garrett, Aliesha ^a   Sarang Sieminski, Alisha L ^a  

^a FRANKLIN W OLIN COLLEGE OF ENGINEERING   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell traction force; Contact guidance; Matrix mechanics; Matrix remodeling; Microvascular networks

Indexed keywords

BIOPHYSICAL PROPERTIES; CAPILLARY MORPHOGENESIS; CELL TRACTION FORCE; CONTACT GUIDANCE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; MATRIX REMODELING; MICROVASCULAR NETWORK; MORPHOLOGICAL CHANGES;

BLOOD VESSELS; COLLAGEN; COMPACTION; ENDOTHELIAL CELLS; MORPHOLOGY; PHYSIOLOGICAL MODELS;

CYTOLOGY;

COLLAGEN FIBER; COLLAGEN GEL;

ARTICLE; CAPILLARY; CELL FUNCTION; CELL STRUCTURE; HUMAN; HUMAN CELL; MICROENVIRONMENT; MICROVASCULAR NETWORK; MORPHOGENESIS; RIGIDITY; TENSION; UMBILICAL VEIN ENDOTHELIAL CELL; ANGIOGENESIS; ANIMAL; BIOLOGICAL MODEL; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; GROWTH, DEVELOPMENT AND AGING; MECHANOTRANSDUCTION; MICROVASCULATURE; PHYSIOLOGY; ULTRASTRUCTURE; YOUNG MODULUS;

ANIMALS; CAPILLARIES; ELASTIC MODULUS; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MICROVESSELS; MODELS, CARDIOVASCULAR; MORPHOGENESIS; NEOVASCULARIZATION, PHYSIOLOGIC;

EID: 84880873828     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4023984     Document Type: Article

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