-
1
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB, Ames BN. 1998 The free radical theory of aging matures. Physiol. Rev. 78, 547-581. (Pubitemid 28182903)
-
(1998)
Physiological Reviews
, vol.78
, Issue.2
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
2
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
doi:10.1093/geronj/11.3.298
-
Harman D. 1956 Aging: A theory based on free radical and radiation chemistry. J Gerontol. 11, 298-300. (doi:10.1093/geronj/11.3.298).
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
3
-
-
57549116867
-
Oxidative stress as a mediator of life history trade-offs: Mechanisms, measurements and interpretation
-
doi:10.1111/j.1461-0248. 2008.01258.x
-
Monaghan P, Metcalfe NB, Torres R. 2009 Oxidative stress as a mediator of life history trade-offs: mechanisms, measurements and interpretation. Ecol. Lett. 12, 75-92. (doi:10.1111/j.1461-0248. 2008.01258.x).
-
(2009)
Ecol. Lett.
, vol.12
, pp. 75-92
-
-
Monaghan, P.1
Metcalfe, N.B.2
Torres, R.3
-
4
-
-
84865861394
-
Oxidative damage, ageing, and life-history evolution: Where now?
-
doi:10.1016/j.tree.2012.06.006
-
Selman C, Blount JD, Nussey DH, Speakman JR. 2012 Oxidative damage, ageing, and life-history evolution: where now? Trends Ecol. Evol. 27, 570-577. (doi:10.1016/j.tree.2012.06.006).
-
(2012)
Trends Ecol. Evol.
, vol.27
, pp. 570-577
-
-
Selman, C.1
Blount, J.D.2
Nussey, D.H.3
Speakman, J.R.4
-
5
-
-
80053629048
-
Molecular and structural antioxidant defenses against oxidative stress in animals
-
doi:10.1152/ajpregu.00034.2011
-
Pamplona R, Costantini D. 2011 Molecular and structural antioxidant defenses against oxidative stress in animals. Am. J. Physiol. Regul. Integr. Comp. Physiol. 301, R843-R863. (doi:10.1152/ajpregu.00034.2011).
-
(2011)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.301
-
-
Pamplona, R.1
Costantini, D.2
-
6
-
-
79952659906
-
The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan
-
doi:10.1002/bies. 201000132
-
Speakman JR, Selman C. 2011 The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan. Bioessays 33, 255-259. (doi:10.1002/bies. 201000132).
-
(2011)
Bioessays
, vol.33
, pp. 255-259
-
-
Speakman, J.R.1
Selman, C.2
-
7
-
-
69949091182
-
Is the oxidative stress theory of aging dead?
-
doi:10.1016/j.bbagen.2009.06.003
-
Perez VI, Bokov A, Van Remmen H, Mele J, Ran Q, Ikeno Y, Richardson A. 2009 Is the oxidative stress theory of aging dead? Biochim. Biophys. Acta 1790, 1005-1014. (doi:10.1016/j.bbagen.2009.06.003).
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 1005-1014
-
-
Perez, V.I.1
Bokov, A.2
Van Remmen, H.3
Mele, J.4
Ran, Q.5
Ikeno, Y.6
Richardson, A.7
-
8
-
-
66749126389
-
Antioxidant defense and aging in c. Elegans: Is the oxidative damage theory of aging wrong?
-
doi:10. 4161/cc.8.11.8595
-
Gems D, Doonan R. 2009 Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong? Cell Cycle 8, 1681-1687. (doi:10. 4161/cc.8.11.8595).
-
(2009)
Cell Cycle
, vol.8
, pp. 1681-1687
-
-
Gems, D.1
Doonan, R.2
-
9
-
-
77952341522
-
Vitamin e supplementation and mammalian lifespan
-
doi:10.1002/mnfr. 200900382
-
Banks R, Speakman JR, Selman C. 2010 Vitamin E supplementation and mammalian lifespan. Mol. Nutr. Food Res. 54, 719-725. (doi:10.1002/mnfr. 200900382).
-
(2010)
Mol. Nutr. Food Res.
, vol.54
, pp. 719-725
-
-
Banks, R.1
Speakman, J.R.2
Selman, C.3
-
10
-
-
39449085542
-
Lifelong alpha-tocopherol supplementation increases the median life span of c57bl/6 mice in the cold but has only minor effects on oxidative damage
-
doi:10. 1089/rej.2007.0586
-
Selman C, McLaren JS, Mayer C, Duncan JS, Collins AR, Duthie GG, Redman P, Speakman JR. 2008 Lifelong alpha-tocopherol supplementation increases the median life span of C57BL/6 mice in the cold but has only minor effects on oxidative damage. Rejuvenation Res. 11, 83-96. (doi:10. 1089/rej.2007.0586).
-
(2008)
Rejuvenation Res.
, vol.11
, pp. 83-96
-
-
Selman, C.1
McLaren, J.S.2
Mayer, C.3
Duncan, J.S.4
Collins, A.R.5
Duthie, G.G.6
Redman, P.7
Speakman, J.R.8
-
11
-
-
33750997598
-
Life-long vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes
-
DOI 10.1016/j.mad.2006.09.008, PII S0047637406002168
-
Selman C, McLaren JS, Meyer C, Duncan JS, Redman P, Collins AR, Duthie GG, Speakman JR. 2006 Lifelong vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes. Mech. Ageing Dev. 127, 897-904. (doi:10.1016/j.mad. 2006.09.008). (Pubitemid 44751894)
-
(2006)
Mechanisms of Ageing and Development
, vol.127
, Issue.12
, pp. 897-904
-
-
Selman, C.1
McLaren, J.S.2
Meyer, C.3
Duncan, J.S.4
Redman, P.5
Collins, A.R.6
Duthie, G.G.7
Speakman, J.R.8
-
12
-
-
84873344743
-
Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: Systematic review and meta-analysis of randomised controlled trials
-
doi:10.1136/bmj.f10
-
Myung SK, Ju W, Cho B, Oh SW, Park SM, Koo BK, Park BJ. 2013 Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials. BMJ 346, f10. (doi:10.1136/bmj.f10).
-
(2013)
BMJ
, vol.346
-
-
Myung, S.K.1
Ju, W.2
Cho, B.3
Oh, S.W.4
Park, S.M.5
Koo, B.K.6
Park, B.J.7
-
13
-
-
84861927005
-
Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
-
doi:10.1002/14651858. CD007176.pub2
-
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. 2012 Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases. Cochrane Database Syst. Rev. 3, CD007176. (doi:10.1002/14651858. CD007176.pub2).
-
(2012)
Cochrane Database Syst. Rev.
, vol.3
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
14
-
-
19944427642
-
Meta-analysis: High-dosage vitamin e supplementation may increase all-cause mortality
-
doi:10.7326/0003-4819-142-1-200501040- 00110
-
Miller 3rd ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. 2005 Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann. Intern. Med. 142, 37-46. (doi:10.7326/0003- 4819-142-1-200501040- 00110).
-
(2005)
Ann. Intern. Med.
, vol.142
, pp. 37-46
-
-
Miller, R.1
Pastor-Barriuso, R.2
Dalal, D.3
Riemersma, R.A.4
Appel, L.J.5
Guallar, E.6
-
15
-
-
79952127458
-
Cats, 'rats, ' and bats: The comparative biology of aging in the 21st century
-
doi:10.1093/icb/icq131
-
Austad SN. 2010 Cats, 'rats, ' and bats: The comparative biology of aging in the 21st century. Integr. Comp. Biol. 50, 783-792. (doi:10.1093/icb/icq131).
-
(2010)
Integr. Comp. Biol.
, vol.50
, pp. 783-792
-
-
Austad, S.N.1
-
16
-
-
46249113763
-
The impact of experimentally elevated energy expenditure on oxidative stress and lifespan in the short-tailed field vole Microtus agrestis
-
DOI 10.1098/rspb.2008.0355, PII W6616GU774825HJ2
-
Selman C, McLaren JS, Collins AR, Duthie GG, Speakman JR. 2008 The impact of experimentally elevated energy expenditure on oxidative stress and lifespan in the short-tailed field vole Microtus agrestis. Proc. R. Soc. B 275, 1907-1916. (doi:10. 1098/rspb.2008.0355). (Pubitemid 351915152)
-
(2008)
Proceedings of the Royal Society B: Biological Sciences
, vol.275
, Issue.1645
, pp. 1907-1916
-
-
Selman, C.1
McLaren, J.S.2
Collins, A.R.3
Duthie, G.G.4
Speakman, J.R.5
-
17
-
-
8544283254
-
The comet assay for DNA damage and repair: Principles, applications, and limitations
-
DOI 10.1385/MB:26:3:249
-
Collins AR. 2004 The comet assay for DNA damage and repair: principles, applications, and limitations. Mol. Biotech. 26, 249-261. (doi:10.1385/MB:26:3: 249). (Pubitemid 41490465)
-
(2004)
Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology
, vol.26
, Issue.3
, pp. 249-261
-
-
Collins, A.R.1
-
19
-
-
80054690858
-
Caloric restriction
-
doi:10.1016/j. mam.2011.07.001
-
Speakman JR, Mitchell SE. 2011 Caloric restriction. Mol. Aspects Med. 32, 159-221. (doi:10.1016/j. mam.2011.07.001).
-
(2011)
Mol. Aspects Med.
, vol.32
, pp. 159-221
-
-
Speakman, J.R.1
Mitchell, S.E.2
-
20
-
-
77649130285
-
Physical activity, fitness and fatness: Relations to mortality, morbidity and disease risk factors
-
doi:10.1111/j.1467-789X.2009.00653.x
-
Fogelholm M. 2010 Physical activity, fitness and fatness: relations to mortality, morbidity and disease risk factors. A systematic review. Obes. Rev. 11, 202- 221. (doi:10.1111/j.1467-789X.2009.00653.x).
-
(2010)
A Systematic Review, Obes. Rev.
, vol.11
, pp. 202-221
-
-
Fogelholm, M.1
-
21
-
-
0033785071
-
Uncoupling to survive? The role of mitochondrial inefficiency in ageing
-
doi:10.1016/S0531-5565(00)00135-2
-
Brand MD. 2000 Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Exp. Gerontol. 35, 811-820. (doi:10.1016/S0531-5565(00) 00135-2).
-
(2000)
Exp. Gerontol
, vol.35
, pp. 811-820
-
-
Brand, M.D.1
-
22
-
-
78651269800
-
Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice
-
doi:10.1111/j.1474-9726.2010.00648.x
-
Keipert S, Voigt A, Klaus S. 2011 Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice. Aging Cell 10, 122-136. (doi:10.1111/j.1474-9726.2010. 00648.x).
-
(2011)
Aging Cell
, vol.10
, pp. 122-136
-
-
Keipert, S.1
Voigt, A.2
Klaus, S.3
-
23
-
-
7044239977
-
Uncoupled and surviving: Individual mice with high metabolism have greater mitochondrial uncoupling and live longer
-
DOI 10.1111/j.1474-9728.2004.00097.x
-
Speakman JR et al. 2004 Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell 3, 87-95. (doi:10.1111/j.1474-9728. 2004.00097.x). (Pubitemid 40246671)
-
(2004)
Aging Cell
, vol.3
, Issue.3
, pp. 87-95
-
-
Speakman, J.R.1
Talbot, D.A.2
Selman, C.3
Snart, S.4
McLaren, J.S.5
Redman, P.6
Krol, E.7
Jackson, D.M.8
Johnson, M.S.9
Brand, M.D.10
-
24
-
-
84455161659
-
Further support to the uncoupling-to-survive theory: The genetic variation of human ucp genes is associated with longevity
-
doi:10.1371/journal.pone. 0029650
-
Rose G, Crocco P, De Rango F, Montesanto A, Passarino G. 2011 Further support to the uncoupling-to-survive theory: The genetic variation of human UCP genes is associated with longevity. PLoS ONE 6, e29650. (doi:10.1371/journal. pone. 0029650).
-
(2011)
PLoS ONE
, vol.6
-
-
Rose, G.1
Crocco, P.2
De Rango, F.3
Montesanto, A.4
Passarino, G.5
-
25
-
-
14944349576
-
Vitamin E mediates cell signaling and regulation of gene expression
-
DOI 10.1196/annals.1331.009
-
Azzi A, Gysin R, Kempna P, Munteanu A, Negis Y, Villacorta L, Visarius T, Zingg JM. 2004 Vitamin E mediates cell signaling and regulation of gene expression. Ann. NY Acad. Sci. 1031, 86-95. (doi:10.1196/annals.1331.009). (Pubitemid 40361745)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1031
, pp. 86-95
-
-
Azzi, A.1
Gysin, R.2
Kempna, P.3
Munteanu, A.4
Negis, Y.5
Villacorta, L.6
Visarius, T.7
Zingg, J.-M.8
-
26
-
-
0034193155
-
Vitamin E: Non-antioxidant roles
-
DOI 10.1016/S0163-7827(00)00006-0, PII S0163782700000060
-
Azzi A, Stocker A. 2000 Vitamin E: non-antioxidant roles. Prog. Lipid Res. 39, 231-255. (doi:10.1016/S0163-7827(00)00006-0). (Pubitemid 30224705)
-
(2000)
Progress in Lipid Research
, vol.39
, Issue.3
, pp. 231-255
-
-
Azzi, A.1
Stocker, A.2
-
27
-
-
66649109663
-
Antioxidants prevent health-promoting effects of physical exercise in humans
-
doi:10.1073/pnas. 0903485106
-
Ristow M, Zarse K, Oberbach A, Kloting N, Birringer M, Kiehntopf M, Stumvoll M, Kahn CR, Bluher M. 2009 Antioxidants prevent health-promoting effects of physical exercise in humans. Proc. Natl Acad. Sci. USA 106, 8665-8670. (doi:10.1073/pnas. 0903485106).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 8665-8670
-
-
Ristow, M.1
Zarse, K.2
Oberbach, A.3
Kloting, N.4
Birringer, M.5
Kiehntopf, M.6
Stumvoll, M.7
Kahn, C.R.8
Bluher, M.9
-
28
-
-
0035884859
-
Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise
-
DOI 10.1016/S0891-5849(01)00640-2, PII S0891584901006402
-
Childs A, Jacobs C, Kaminski T, Halliwell B, Leeuwenburgh C. 2001 Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Radic. Biol. Med. 31, 745-753. (doi:10.1016/S0891-5849(01) 00640-2). (Pubitemid 32835255)
-
(2001)
Free Radical Biology and Medicine
, vol.31
, Issue.6
, pp. 745-753
-
-
Childs, A.1
Jacobs, C.2
Kaminski, T.3
Halliwell, B.4
Leeuwenburgh, C.5
-
29
-
-
77953543902
-
The lipophilic antioxidants a-tocopherol and coenzyme q10 reduce the replicative lifespan of saccharomyces cerevisiae
-
doi:10.1016/j.freeradbiomed.2010. 04.008
-
Lam YT, Stocker R, Dawes IW. 2010 The lipophilic antioxidants a-tocopherol and coenzyme Q10 reduce the replicative lifespan of Saccharomyces cerevisiae. Free Radic. Biol. Med. 49, 237-244. (doi:10.1016/j.freeradbiomed. 2010. 04.008).
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 237-244
-
-
Lam, Y.T.1
Stocker, R.2
Dawes, I.W.3
-
30
-
-
73449135823
-
Ageing in nematodes: Do antioxidants extend lifespan in caenorhabditis elegans?
-
doi:10.1007/s10522-009-9223-5
-
Pun PB, Gruber J, Tang SY, Schaffer S, Ong RL, Fong S, Ng LF, Cheah I, Halliwell B. 2010 Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans? Biogerontology 11, 17-30. (doi:10.1007/s10522-009-9223- 5).
-
(2010)
Biogerontology
, vol.11
, pp. 17-30
-
-
Pun, P.B.1
Gruber, J.2
Tang, S.Y.3
Schaffer, S.4
Ong, R.L.5
Fong, S.6
Ng, L.F.7
Cheah, I.8
Halliwell, B.9
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