A high-throughput screen of the GTPase activity of Escherichia coli EngA to find an inhibitor of bacterial ribosome biogenesis

Journal of Biomolecular Screening

Volumn 18, Issue 7, 2013, Pages 830-836

  Bharat, Amrita ^a   Blanchard, Jan E ^a,b   Brown, Eric D ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

EngA; enzyme screen; GTPase; ribosome biogenesis

Indexed keywords

DIHYDROFOLATE REDUCTASE; ENGA PROTEIN; ESCHERICHIA COLI PROTEIN; GARCINOL; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE INHIBITOR; HYDROLASE INHIBITOR; MAC 0080023; MAC 0174809; MAC 0182099; MAC 0182344; PHOSPHATE; THEAFLAVIN MONOGALLATE; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME INHIBITION; ENZYME SPECIFICITY; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RIBOSOME;

EID: 84880790679     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113486001     Document Type: Article

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