Effectiveness of Modified Hodge Test to detect NDM-1 Carbapenemases: An experience from Pakistan

Journal of the Pakistan Medical Association

Volumn 63, Issue 8, 2013, Pages 955-960

  Sultan, Binish Arif ^a   Khan, Erum ^a   Hussain, Fatima ^a   Nasir, Amna ^a   Irfan, Seema ^a  

^a AGA KHAN UNIVERSITY   (Pakistan)

Author keywords

Metallo beta lactamase; Modified Hodge Test; NDM 1; Pakistan

Indexed keywords

AMIKACIN; AZTREONAM; CARBAPENEMASE; CEFIXIME; CEFOTAXIME; CEFTRIAXONE; FOSFOMYCIN; MEROPENEM; METALLO BETA LACTAMASE; OFLOXACIN; PENICILLIN DERIVATIVE; POLYMYXIN B;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM IDENTIFICATION; BLOOD CULTURE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DESCRIPTIVE RESEARCH; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DISK DIFFUSION; ENTEROBACTERIACEAE; EPSILOMETER TEST; MINIMUM INHIBITORY CONCENTRATION; MODIFIED HODGE TEST; NONHUMAN; PAKISTAN; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE; PROSPECTIVE STUDY; PUS; SENSITIVITY AND SPECIFICITY; TRACHEAL ASPIRATION PROCEDURE; URINE CULTURE;

EID: 84880760948     PISSN: 00309982     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Webster DP, Gaulton T, Woodford N, Pike R, Turton J, Perry C, et al. Emergence of carbapenem resistance due to porin loss in an extended-spectrum ß-lactamase (ESBL)-producing Klebsiella pneumoniae strain during meropenem therapy. Int J Antimicrob Agents 2010; 36: 575-6.
2. Deshpande LM, Jones RN, Fritsche TR, Sader HS. Occurrence and characterization of carbapenemase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program (2000-2004). Microb Drug Resist 2006;12: 223-30.
3. Queenan AM, Bush K. Carbapenemases: the versatile betalactamases. Clin Microbiol Rev 2007; 20: 440-58.
4. Centers for Disease Control and Prevention. Detection of Enterobacteriaceae isolates carrying metallo-ß-lactamase-United States, 2010. MMWR Morb Mortal Wkly Rep 2010; 59: 750.
5. Kumarasamy KK, Toleman MA, Walsh TR, Bagaria J, Butt F, Balakrishnan R, et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 2010; 10: 597-602.
6. Mushtaq S, Irfan S, Sarma JB, Doumith M, Pike R, Pitout J, et al. Phylogenetic diversity of Escherichia coli strains producing NDMtype carbapenemases. J Antimicrob Chemother 2011; 66: 2002-5.
7. Cohen Stuart J, Leverstein-Van Hall MA, Dutch Working Party on the Detection of Highly Resistant Microorganisms. Guideline for phenotypic screening and confirmation of carbapenemases in Enterobacteriaceae. Int J Antimicrob Agents 2010; 36: 205-10.
8. Birgy A, Bidet P, Genel N, Doit C, Decré D, Arlet G, et al. Phenotypic screening of carbapenemases and associated ß-lactamases in carbapenem-resistant Enterobacteriaceae. J Clin Microbiol 2012; 50: 1295-302.
9. Pakistan Antimicrobial Resistance Network. Antibiotic Susceptibility Report. (Online) 2009 (Cited September 16, 2009). Available from URL: http://www.parn.org.pk/index_files/doc/Antibiogram.pdf.
10. Khan E, Schneiders T, Zafar A, Aziz E, Parekh A, Hasan R. Emergence of CTX-M Group 1-ESBL producing Klebsiella pneumonia from a tertiary care centre in Karachi, Pakistan. J Infect Dev Ctries 2010; 4: 472-6.
11. CLSI. Performance standards for antimicrobial susceptibility testing-CLSI document M100-S19. 19th informational supplement. 2010; 30: 51-
12. ABbiodisk Solna, Sweden. Available at: http://www.biomerieuxdiagnostics.com
13. CLSI. Performance standards for antimicrobial susceptibility testing-CLSI document M100-S20. 21st informational supplement. 2011; 30:51-
14. Perry JD, Naqvi SH, Mirza IA, Alizai SA, Hussain A, Ghirardi S, et al. Prevalence of faecal carriage of Enterobacteriaceae with NDM-1 carbapenemase at military hospitals in Pakistan, and evaluation of two chromogenic media. J Antimicrob Chemother 2011; 66: 2288-94.
15. CLSI. Performance standards for antimicrobial susceptibility testing-CLSI document M100-S22. 22nd informational supplement. 2012; 30: 51-2.
16. Leverstein-Van Hall MA, Stuart JC, Voets GM, Versteeg D, Tersmette T, Fluit AC. Global spread of New Delhi metallo-ß-lactamase 1. Lancet Infect Dis 2010;10: 830-1.
17. Walsh TR. Emerging carbapenemases: a global perspective. Int J Antimicrob Agents 2010;(36 Suppl 3): S8-14.