Schizonepeta tenuifolia inhibits the development of atopic dermatitis in mice

Phytotherapy Research

Volumn 27, Issue 8, 2013, Pages 1131-1135

  Choi, You Yeon ^a   Kim, Mi Hye ^a   Kim, Jong Hyun ^a   Jung, Hyuk Sang ^a   Sohn, Youngjoo ^a   Choi, Young Jin ^a   Hwang, Man Ki ^a   Kim, Sung Hoon ^a   Kim, Jinju ^a   Yang, Woong Mo ^a  

^a Kyung Hee University   (South Korea)

Author keywords

atopic dermatitis; cytokine; IgE; MAPKs; Schizonepeta tenuifolia

Indexed keywords

ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; PULEGONE; SCHIZONEPETA TENUIFOLIA EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; CYTOKINE RELEASE; DERMIS; DRUG EFFECT; ENZYME INHIBITION; EPIDERMIS; FEMALE; HISTOPATHOLOGY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; MEDICINAL PLANT; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SCHIZONEPETA TENUIFOLIA; SKINFOLD THICKNESS; UPREGULATION;

MUS; SCHIZONEPETA TENUIFOLIA;

ATOPIC DERMATITIS; CYTOKINE; IGE; MAPKS; SCHIZONEPETA TENUIFOLIA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DERMATITIS, ATOPIC; DINITROCHLOROBENZENE; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOGLOBULIN E; INTERLEUKIN-6; LAMIACEAE; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PLANT EXTRACTS; SKIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84880751296     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4833     Document Type: Article

References (20)

1. Boisleve F, Kerdine-Romer S, Rougier-Larzat N, et al,. 2004. Nickel and DNCB induce CCR7 expression on human dendritic cells through different signalling pathways: Role of TNF-alpha and MAPK. J Invest Dermatol 123: 494-502.
2. Chan LS, Robinson N, Xu L,. 2001. Expression of interleukin-4 in the epidermis of transgenic mice results in a pruritic inflammatory skin disease: an experimental animal model to study atopic dermatitis. J Invest Dermatol 117: 977-983.
3. Del RJ, Friedlander SF,. 2005. Corticosteroids: options in the era of steroid-sparing therapy. J Am Acad Dermatol 53 (Suppl 1): S50-58.
4. Friedmann PS,. 2006. Contact sensitisation and allergic contact dermatitis: immunobiological mechanisms. Toxicology Letters 162: 49-54.
5. Galli SJ, Tsai M, Piliponsky AM,. 2008. The development of allergic inflammation. Nature 454: 445-454.
6. Jin H, He R, Oyoshi M, et al,. 2009. Animal models of atopic dermatitis. J Invest Dermatol 129: 31-40.
7. Kang H, Han SW, Hong JW, et al,. 2010. Suppression of tumour necrosis factor-a by Schizonepeta tenuifolia water extract via inhibition of IkBa degradation and Jun N-terminal kinase/stress-activated protein kinase activation. J Pharm Sci. 62: 1069-1076
8. Kim SH, Shin TY,. 2009. Anti-inflammatory effect of leaves of Eriobotrya japonica correlating with attenuation of p38 MAPK, ERK, and NF-κB activation in mast cells. Toxicol in Vitro 23: 1215-1219.
9. Kim SJ, KimJS, Choi YY, et al,. 2008. Anti-inflammatory activity of Schizonepeta tenuifolia through the inhibition of MAPK phosphorylation in mouse peritoneal macrophages. Am J Chin Med 36 (6): 1145-1158.
10. Kimura T, But, P PH, Guo JX, et al,. 1986. International Collation of Traditional and Folk Medicine (1). World Scientific Singapore 147-148.
11. Navi D, Saegusa J, Liu FT,. 2007. Mast cells and immunological skin diseases. Clin Rev Allergy Immunol 33: 144-155.
12. Norris DA,. 2005. Mechanisms of action of topical therapies and the rationale for combination therapy. J Am Acad Dermatol 53 (Suppl 1): S17-25.
13. Ponyai G, Temesvari E, Karpati S,. 2007. Adulthood atopic dermatitis: epidemiology, clinical symptoms, provoking and prognostic factors. Orvosi Hetilap 148: 21-26.
14. Prussin C, Metcalfe DD,. 2003. IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol 111: S486-S494.
15. Siraganian RP,. 2003. Mast cell signal transduction from the high-affinity IgE receptor. Curr Opin Immunol 15: 639-646.
16. Smahi A, Courtois G, Rabia SH, et al,. 2002. The NF-kB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes. Hum Mol Genet. 11: 2371-2375.
17. Wuertz K, Vo N, Kletsas D, et al,. 2012. Inflammatory and catabolic signalling in intervertebral discs: The roles of NF-kB and MAP Kinases. Eur Cell Mater 23: 103-20.
18. Yamahara J, Matsuda HH, Watanabe H, et al,. 1980. Biologically active principles of crude drugs. Analgesic and anti-inflammatory effects of "Keigai (Schizonepeta tenuifolia Briq)". Yakugaku Zasshi 100: 713-717.
19. Yoo JS, Kim DK, Kim SH, et al,. 2011. Anti-allergic Effects of Schizonepeta tenuifolia on Mast Cell-Mediated Allergy Model. Nat Prod Sci 17 (3): 239-244.
20. Zhang L, Tinkle SS,. 2000. Chemical activation of innate and specific immunity in contact dermatitis. J Invest Dermatol 115: 168-176.