Nemo-Like Kinase Associated with Proliferation and Apoptosis by c-Myb Degradation in Breast Cancer

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Huang, Yeqing ^a   Jiang, Ying ^b   Lu, Weiqi ^b   Zhang, Yong ^b  

^a NANTONG MEDICAL COLLEGE   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; I KAPPA B KINASE GAMMA; KI 67 ANTIGEN; NEMO LIKE KINASE; PROGESTERONE RECEPTOR; PROTEIN BCL 2; PROTEIN C MYB; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER TISSUE; CELL CYCLE PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR VOLUME; UBIQUITINATION; WESTERN BLOTTING;

APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KI-67 ANTIGEN; MCF-7 CELLS; MIDDLE AGED; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYB;

EID: 84880747468     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069148     Document Type: Article

References (41)

1. Sonia M, Hailong W, Priyasri C, Kounosuke W, (2007) Wnt pathway and breast cancer. Frontiers in Bioscience 12: 4020-33.
2. Chie KI, Jun NT, Jun T, Teruaki N, Tohru I, et al. (2004) Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK. Genes Dev 18: 816-29.
3. Ishikawa T, Shimizu D, Kito A, Ota I, Sasaki T, et al. (2012) Breast cancer manifested by hematologic disorders. J Thorac Dis 4: 650-4.
4. Eriko O, Toshiyasu G, Atsushi S, Misun K, Shunichiro I, et al. (2010) Nemo-Like Kinase, an Essential Effector of Anterior Formation,Functions Downstream of p38 Mitogen-Activated Protein Kinase. Mol Cell Biol 30: 675-83.
5. Daemen A, (2012) An update on the genomic landscape of breast cancer: new opportunity for personalized therapy? Transl Cancer Res 1: 279-82.
6. Barbara KB, Benjamin AP, Raymond LE, (1998) Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus. Proc. Natl. Acad. Sci. U. S. A. 95: 963-8.
7. Ivana M, Kristi C, Sharon MG, Kristen M, Esther MV, (2002) Drosophila nemo is an essential gene involved in the regulation of programmed cell death. Mech Dev 119: 9-20.
8. Kaletta T, Schnabel H, Schnabel R, (1997) Binary specification of the embryonic lineage in Caenorhabditis elegans. Nature 390: 294-8.
9. Verheyen EM, Mirkovic I, MacLean SJ, Langmann C, Andrews BC, et al. (2001) The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila development. Mech Dev 101: 119-32.
10. Katayoon HE, Lisha GB, Tiffany EMP, Xizhang S, Robert LV, et al. (2009) Nemo-LikeKinase Induces Apoptosis and Inhibits Androgen Receptor Signaling in Prostate Cancer Cells. Prostate 69: 1481-92.
11. Cui G, Li Z, Shao B, Zhou WF, Liu T, et al, (2011) Clinical and biological significance of Nemo-like kinase expression in glioma. J Clin neurosci 18: 271-5.
12. Graf T, Altieri M, Venturelli D, (1992) Myb: a transcriptional activator linking proliferation and differentiation in hematopoietic cells. Curr Opin Genet Dev 2: 249-55.
13. Weston K, (1998) Myb proteins in life, death and differentiation. Curr Opin Genet Dev 8: 76-81.
14. Gewirtz AM, Calabretta B, (1988) A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science 242: 1303-6.
15. Gewirtz AM, Anfossi G, Venturelli D, Valpreda S, Sims R, et al. (1989) G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb. Science 245: 180-3.
16. Anfossi G, Gewirtz AM, Calabretta B, (1989) An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc Natl Acad Sci U S A 86: 3379-83.
17. Melani C, Rivoltini L, Parmiani G, Calabretta B, Colombo MP, (1991) Inhibition of proliferation by c-myb antisense oligodeoxynucleotides in colon adenocarcinoma cell lines that express c-myb. Cancer Res 51: 2897-901.
18. Zorbas M, Sicurella C, Bertoncello I, venter D, Ellis S, et al. (1999) c-Myb is critical for murine colon development. Oncogene 18: 5821-30.
19. Hodges LC, Cook JD, Lobenhofer EK, Li L, Bennett L, et al. (2003) Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells. Mol Cancer Res 1: 300-11.
20. Kauraniemi P, Hedenfalk I, Persson K, Duggan DJ, Tanner M, et al. (2000) MYB oncogene amplification in hereditary BRCA1 breast cancer. Cancer Res 60: 5323-8.
21. Villa AE, Guzman LA, Poptic EJ, Labhasetwar AD, Souza S, et al. (1995) Effects of antisense c-myb oligonucleotides on vascular smooth muscle cell proliferation and response to vessel wall injury. Circ Res 76: 505-13.
22. Annamaria B, Barbara B, Igea D, (2001) c-Myc and Bcl-x over-expression predicts poor prognosis in colorectal cancer: clinical and experimental findings. Am J Pathol 158: 1289-99.
23. Thompson M, Flegg R, Westin E, Ramsay R, (1997) Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines. Oncogene 14: 1715-23.
24. Thompson M, Flegg R, Westin E, Ramsay R, (1997) Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines. Oncogene 14: 1715-23.
25. Ramsay RG, Thompson MA, Hayman JA, Reid G, Gonda TJ, et al. (1992) Myb expression is higher in malignant human colonic carcinoma and premalignant adenomatous polyps than in normal mucosa. Cell Growth Differ 3: 723-30.
26. Melani C, Rivoltini L, Parmiani G, Calabretta B, Colombo M, (1991) Inhibition of proliferation by c-myb antisense oligodeoxynucleotides in colon adenocarcinoma cell lines that express c-myb. Cancer Research 51: 2897-901.
27. Yvette D, Ramsay GR, Thomas JG, (2010) MYB suppresses differentiation and apoptosis of human breast cancer cells. Breast Cancer Research 12: R55.
28. Toshihiro K, Teruaki N, Chie KI, Yoichi S, Shunsuke I, (2005) The Wnt-NLK Signaling Pathway Inhibits A-Myb Activity by Inhibiting the Association with Coactivator CBP and Methylating Histone H3. Mol Bio Cell 16: 4705-13.
29. Wodarz A, Nusse R, (1998) Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 14: 59-88.
30. Civenni G, Holbro T, Hynes NE, (2003) Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells. EMBO Rep 4: 166-71.
31. Jordan BK, Shen JH, Olaso R, Ingraham HA, Vilain E, (2003) Wnt4 over-expression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy. Proc Natl Acad Sci USA 100: 10866-71.
32. Chie KI, Teruaki N, Tsuyoshi T, Nobumoto W, Keiichi IN, et al. (2008) Fbxw7 Acts as an E3 Ubiquitin Ligase That Targets c-Myb for Nemo-like Kinase (NLK)-induced Degradation. J Biol Chem 283: 30540-8.
33. Atul K, Clement ML, Reddy EP, (2003) c-Myc Is Essential but Not Sufficient for c-Myb-mediated Block ofGranulocytic Differentiation. J Biol Chem 278: 11480-8.
34. Feng F, Michael AR, Charles VC, (2009) Role of c-Myb during Prolactin-Induced Signal Transducer and Activator of Transcription 5a Signaling in Breast Cancer Cells. Endocrinology 150: 1597-606.
35. Kim Sh, Kim YS, Lee JW, Chung Jk, (2010) Regulation of FOXO1 by TAK1-Nemo-like Kinase Pathway. J Biol Chem 285: 8122-9.
36. Jun Y, Akira T, Tesshi Y, Michiie S, Takao S, et al. (2003) Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells. Biochem Bioph Res Co 308: 227-33.
37. Persson M, Andren Y, Mark J, Horlings HM, Persson F, et al. (2009) Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc Natl Acad Sci 106: 18740-4.
38. Aaron RT, Joel SP, Katherine AH, Charles MP, (2010) Potential Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast Cancer. PLoS ONE 5: e13073.
39. Frampton J, Ramqvist T, Graf T, (1996) v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells. Genes Dev 10: 2720-31.
40. Salomoni P, Perrotti D, Martinez R, Francheschi C, Calahretta B, (1997) Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity. Proc Nati Acad Sci USA 94: 3296-301.
41. Zorbas M, Sicurella C, Bertoncello I, Venter D, Ellis S, et al. (1999) c-Myb is critical for murine colon development. Oncogene 18: 5821-30.