Vertical sleeve gastrectomy is effective in two genetic mouse models of glucagon-like peptide 1 receptor deficiency

Diabetes

Volumn 62, Issue 7, 2013, Pages 2380-2385

  Wilson Pérez, Hilary E ^a   Chambers, Adam P ^a   Ryan, Karen K ^a   Li, Bailing ^a   Sandoval, Darleen A ^a   Stoffers, Doris ^b   Drucker, Daniel J ^c   Pérez Tilve, Diego ^a   Seeley, Randy J ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON LIKE PEPTIDE 1 RECEPTOR; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; PEPTIDE; VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARIATRIC SURGERY; BODY FAT; BODY WEIGHT; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; FOOD INTAKE; FOOD PREFERENCE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HORMONE RELEASE; HYPOTHESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SLEEVE GASTRECTOMY; WEIGHT REDUCTION; WILD TYPE; ANIMAL; BODY COMPOSITION; DRUG EFFECT; EATING; GASTRECTOMY; GENETICS; INSULIN RESISTANCE; KNOCKOUT MOUSE; METABOLISM; METHODOLOGY; OBESITY; PHYSIOLOGY; POSTPRANDIAL STATE;

ANIMALS; BODY COMPOSITION; BODY WEIGHT; EATING; GASTRECTOMY; GLUCAGON-LIKE PEPTIDE 1; INSULIN RESISTANCE; MICE; MICE, KNOCKOUT; OBESITY; PEPTIDES; POSTPRANDIAL PERIOD; RECEPTORS, GLUCAGON; VENOMS;

EID: 84880743041     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1498     Document Type: Article

References (23)

1. Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006;368:1696- 1705
2. Pories WJ. Bariatric surgery: risks and rewards. J Clin Endocrinol Metab 2008;93(Suppl. 1):S89-S96
3. Abbatini F, Rizzello M, Casella G, et al. Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetes. Surg Endosc 2010;24:1005-1010
4. Karamanakos SN, Vagenas K, Kalfarentzos F, Alexandrides TK. Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: A prospective, double blind study. Ann Surg 2008;247:401-407
5. Pereferrer FS, Gonzàlez MH, Rovira AF, Blasco SB, Rivas AM, del Castillo Déjardin D. Influence of sleeve gastrectomy on several experimental models of obesity: metabolic and hormonal implications. Obes Surg 2008; 18:97-108
6. Peterli R, Wölnerhanssen B, Peters T, et al. Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: A prospective randomized trial. Ann Surg 2009;250:234-241
7. Stefater MA, Perez-Tilve D, Chambers AP, et al. Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity. Gastroenterology 2010;138:2426-2436, e2421-e2423
8. Stefater MA, Sandoval DA, Chambers AP, et al. Sleeve gastrectomy in rats improves postprandial lipid clearance by reducing intestinal triglyceride secretion. Gastroenterology 2011;141:939-949, e931-e934
9. Schauer PR, Kashyap SR, Wolski K, et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med 2012;366:1567-1576
10. Chambers AP, Jessen L, Ryan KK, et al. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology 2011;141:950-958
11. Cummings DE, Overduin J, Shannon MH, Foster-Schubert KE; 2004 ABS Consensus Conference. Hormonal mechanisms of weight loss and diabetes resolution after bariatric surgery. Surg Obes Relat Dis 2005;1:358-368
12. Ayala JE, Bracy DP, James FD, Burmeister MA, Wasserman DH, Drucker DJ. Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet- induced insulin resistance. Endocrinology 2010;151:4678-4687
13. Scrocchi LA, Brown TJ, MaClusky N, et al. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med 1996;2:1254-1258
14. Schwenk F, Baron U, Rajewsky K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res 1995;23:5080-5081
15. Wilson-Perez HE, Chambers AP, Sandoval DA, et al. The effect of vertical sleeve gastrectomy on food choice in rats. Int J Obes (Lond) 2013;37:288- 295
16. le Roux CW, Welbourn R, Werling M, et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg 2007;246:780-785
17. Kindel TL, Yoder SM, Seeley RJ, D'Alessio DA, Tso P. Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor- mediated mechanism. J Gastrointest Surg 2009;13:1762- 1772
18. Salehi M, Prigeon RL, D'Alessio DA. Gastric bypass surgery enhances glucagon-like peptide 1-stimulated postprandial insulin secretion in humans. Diabetes 2011;60:2308- 2314
19. Stylopoulos N, Hoppin AG, Kaplan LM. Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats. Obesity (Silver Spring) 2009;17:1839-1847
20. Lovshin J, Estall J, Yusta B, Brown TJ, Drucker DJ. Glucagon-like peptide (GLP)-2 action in the murine central nervous system is enhanced by elimination of GLP-1 receptor signaling. J Biol Chem 2001;276:21489-21499
21. Pederson RA, Satkunarajah M, McIntosh CH, et al. Enhanced glucosedependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice. Diabetes 1998;47:1046-1052
22. Meier JJ, Nauck MA. GIP as a potential therapeutic agent? Horm Metab Res 2004;36:859-866
23. Hansotia T, Maida A, Flock G, et al. Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure. J Clin Invest 2007;117:143- 152