Direct comparison of radiation dosimetry of six PET tracers using human whole-body imaging and murine biodistribution studies

Annals of Nuclear Medicine

Volumn 27, Issue 3, 2013, Pages 285-296

  Sakata, Muneyuki ^a   Oda, Keiichi ^a   Toyohara, Jun ^a   Ishii, Kenji ^a   Nariai, Tadashi ^a,b   Ishiwata, Kiichi ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

PET; Radiation dosimetry; Whole body distribution

Indexed keywords

1 (3, 4 DIMETHOXYPHENETHYL) 4 (3 PHENYLPROPHYL)PIPERAZINE C 11; 4 BORONO 2 FLUOROPHENYLALANINE F 18; 4' THIOTHYMIDINE C 11; 8 (3,4,5 TRIMETHOXYSTYRYL) 1,3,7 TRIMETHYLXANTHINE C 11; 8 DICYCLOPROPYLMETHYL 1 METHYL 3 PROPYLXANTHINE C 11; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSIMETRY; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; IMAGE RECONSTRUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; WHOLE BODY PET;

ADULT; ANIMALS; HUMANS; MALE; MICE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; RADIOMETRY; TISSUE DISTRIBUTION; WHOLE BODY IMAGING; YOUNG ADULT;

EID: 84880698887     PISSN: 09147187     EISSN: 18646433     Source Type: Journal    
DOI: 10.1007/s12149-013-0685-9     Document Type: Article

References (32)

1. 11C-labeled PET tracers for first-in-human studies. Eur J Nucl Med Mol Imaging. 2012;39:544-7.
2. van der Aart J, Hallett WA, Rabiner EA, Passchier J, Comley RA. Radiation dose estimates for carbon-11-labelled PET tracers. Nucl Med Biol. 2012;39:305-14.
3. Santens P, De Vos F, Thierens H, et al. Biodistribution and dosimetry of carbon-11-methoxyprogabidic acid, a possible ligand for GABA-receptors in the brain. J Nucl Med. 1998;39:307-10.
4. 11C]CP-126,998, a brain selective enzyme inhibitor. Synapse. 2002;45:1-9.
5. 11C]choline: a comparison between rat and human data. Eur J Nucl Med Mol Imaging. 2010;37:874-83.
6. 11C]CHIBA-1001 in humans. Nucl Med Biol. 2011;38:443-8.
7. Toyohara J, Nariai T, Sakata M, et al. Whole-body distribution and brain tumor imaging with 11C-4DST: a pilot study. J Nucl Med. 2011;52:1322-8.
8. 1 receptors in the cat brain. Ann Nucl Med. 2000;14:285-92.
9. 1 receptors by positron emission tomography. Ann Nucl Med. 2002;16:377-82.
10. 2A receptors by positron emission tomography. Ann Nucl Med. 2003;17:205-11.
11. 18F]fluoro-d, l-phenylalanine: a target compound for PET and boron neutron capture therapy. Appl Radiat Isot. 1991;42:325-8.
12. 1 receptors. Nucl Med Biol. 2000;27:255-61.
13. 2a receptor ligand. J Nucl Med. 2000;41:345-54.
14. 11C]CHIBA-1001 for mapping α7 nicotinic receptors by positron emission tomography. Ann Nucl Med. 2009;23:301-9.
15. 18F]fluoro-L-DOPA: use of 4-O-pivaloyl-L-DOPA as a suitable precursor for routine production. Appl Radiat Isot. 1993;44:755-9.
16. Fujiwara T, Watanuki S, Yamamoto S, et al. Performance evaluation of a large axial field-of-view PET scanner: SET-2400 W. Ann Nucl Med. 1997;11:307-13.
17. Meikle SR, Bailey DL, Hooper PK, et al. Simultaneous emission and transmission measurements for attenuation correction in whole-body PET. J Nucl Med. 1995;36:1680-8.
18. Stabin MG, Sparks RB, Crowe E. OLINDA/EXM: the second generation personal computer software for internal dose assessment in nuclear medicine. J Nucl Med. 2005;46:1023-7.
19. Kirschner AS, Ice RD, Beierwaltes WH. Radiation dosimetry of 131I-19-iodocholesterol: the pitfalls of using tissue concentration data - reply. J Nucl Med. 1975;16:248-9.
20. International Commission on Radiological Protection. ICRP Publication 60: 1990 recommendations of the International Commission on Radiological Protection. Ann ICRP. 1991;21:493-502.
21. 11C-(R)-PK11195, the prototypic PET ligand to image inflammation. Eur J Nucl Med Mol Imaging. 2010;37:606-12.
22. 18F]fluoroethyl)-l-tyrosine. Eur J Nucl Med Mol Imaging. 2003;30:519-24.
23. Brown WD, Oakes TR, DeJesus OT, et al. Fluorine-18-fluoro-L-DOPA dosimetry with carbidopa pretreatment. J Nucl Med. 1998;39:1884-91.
24. Deloar HM, Fujiwara T, Shidahara M, et al. Estimation of absorbed dose for 2-[F-18]fluoro-2-deoxy-d-glucose using whole-body positron emission tomography and magnetic resonance imaging. Eur J Nucl Med. 1998;25:565-74.
25. 18F- labeled radiopharmaceuticals. J Radiat Res. 1991;32:243-61.
26. Lin JH. Species similarities and differences in pharmacokinetics. Drug Metab Dispos. 1995;23:1008-21.
27. 11C]thiothymidine as a tumor proliferation imaging agent in mice. Nucl Med Biol. 2008;35:67-74.
28. Chiu SH, Huskey SW. Species differences in N-glucuronidation. Drug Metab Dispos. 1998;26:838-47.
29. Luoto P, Laitinen I, Suilamo S, Någren K, Roivainen A. Human dosimetry of carbon-11 labeled N-butan-2-yl-1-(2-chlorophenyl)-N- methylisoquinoline-3-carboxamide extrapolated from whole-body distribution kinetics and radiometabolism in rats. Mol Imaging Biol. 2010;12:435-42.
30. 18F]fluoro-L-dopa. J Nucl Med. 1985;26:931-5.
31. 18F]fluoroethyl)-l-tyrosine as oncologic PET tracer. Appl Radiat Isot. 2003;58:219-25.
32. International Commission on Radiological Protection. ICRP Publication 80. Recalculated dose data for 19 frequently used radiopharmaceuticals from ICRP Publication 53. Ann ICRP. 1998;28:47-83.