Reactive oxygen species and extracellular signal-regulated kinase 1/2 mediate hexachlorobenzene-induced cell death in frtl-5 rat thyroid cells

Toxicological Sciences

Volumn 134, Issue 2, 2013, Pages 276-290

  Chiappini, Florencia ^a   Pontillo, Carolina ^a   Randi, Andrea S ^a   Alvarez, Laura ^a   De Pisarev, Diana L Kleiman ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Apoptosis; ERK1 2; FRTL 5 cells; Hexachlorobenzene; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; APOPTOSIS INDUCING FACTOR; CASPASE 10; CASPASE 3; CASPASE 8; CYTOCHROME C; HEXACHLOROBENZENE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TROLOX C;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS MEMBRANE; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CYTOSOL; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME ACTIVATION; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION; THYROID CELL;

APOPTOSIS; ERK1/2.; FRTL-5 CELLS; HEXACHLOROBENZENE; REACTIVE OXYGEN SPECIES;

ANIMALS; APOPTOSIS; CASPASES; CELL LINE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEXACHLOROBENZENE; MITOCHONDRIA; PHOSPHORYLATION; RATS; REACTIVE OXYGEN SPECIES; THYROID GLAND;

EID: 84880684046     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft117     Document Type: Article

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