Cloning of the Xuhuai goat PPARγ gene and the preparation of transgenic sheep

Biochemical Genetics

Volumn 51, Issue 7-8, 2013, Pages 543-553

  Qin, Yurong ^a   Chen, Hao ^b   Zhang, Yani ^a   Zhu, Caiye ^a   Gao, Bo ^a   Yin, Yanhui ^a   Li, Wei ^a   Shi, Qingqing ^a   Zheng, Mengmeng ^a   Xu, Qi ^a   Song, Jiuzhou ^c   Li, Bichun ^a  

^a YANGZHOU UNIVERSITY   (China)

^b MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

Peroxisome proliferator activated receptor; Transgenic sheep; Xuhuai goat

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CHICKEN; CONTROLLED STUDY; COW; FAT CONTENT; FEMALE; FLAVOR; FOOD QUALITY; GENE EXPRESSION; GENE SEQUENCE; GENETIC CODE; GOAT; IN VITRO STUDY; INTRAABDOMINAL FAT; MALE; MEAT; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PPARY GENE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SWINE; TRANSGENIC SHEEP; WESTERN BLOTTING;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CATTLE; CHICKENS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GOATS; GREEN FLUORESCENT PROTEINS; MEAT; MICE; NIH 3T3 CELLS; PLASMIDS; PPAR GAMMA; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, PROTEIN; SHEEP, DOMESTIC; SPECIES SPECIFICITY; SWINE;

CAPRA HIRCUS; OVIS ARIES; SUIDAE;

EID: 84880579774     PISSN: 00062928     EISSN: 15734927     Source Type: Journal    
DOI: 10.1007/s10528-013-9585-x     Document Type: Article

References (18)

1. Braissant O, Foufelle F, Scotto C, Dauça M, Wahli W (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, and -γ in the adult rat. Endocrinology 137:354-366
2. Chen Z, Zhao XF, Jiang XL, Guo XL, lv ZZ, Zhou HM, Xu NY (2011) Association of PPARγ2 polymorphisms with carcass and meat quality traits in a Pietrain × Jinhua F2 population. Genet Mol Biol 34:56-61
3. Desvergne B, Wahli W (1999) Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20:649-688
4. Dreyer C, Krey G, Keller H, Givel F, Helftenbein G, Wahli W (1992) Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68:879-887
5. Evan, Bruce MP (2001) PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem. doi: 10.1074/jbc.R100034200
6. Grindflek E, Sundvold H, Rothschild MF, Plastow G, Lien S (2004) Investigation of a peroxisome proliferator-activated receptor gamma haplotype effect on meat quality and carcass traits in pigs. Animal Genet 35:238-241
7. Hao C, Li Q, Qiao Y, Liu Z, Shao D, Li W, Lin J, Wu F, Shen B, Xie Z (2008) Association of the H-FABP and PPARγ gene expression with intramuscular fat content in Hu sheep muscles. Sci Agric Sinica 41:3776-3783
8. Hermesch S, Luxford BG, Graser AU (2000) Genetic parameters for lean meat yield, meat quality, reproduction and feed efficiency traits for Australian pigs. Livest Prod Sci 65:249-259
9. Houseknecht KL, Bidwell CA, Portocarrero CP, Spurlock ME (1998) Expression and cDNA cloning of porcine peroxisome proliferator-activated receptor gamma (PPAR gamma). Gene 225:89-96
10. Issemann I, Green S (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347:645-650
11. Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci USA 91(15):7355-7359
12. Lemberger T, Desvergne B, Wahli W (1996) Peroxisome proliferator- activated receptors: a nuclear receptor signaling pathway in lipid physiology. Ann Rev Cell Dev Biol 12:335-363
13. Lin YQ, Kuang LD, Xu YO (2010) Cloning and expression profiling of peroxisome proliferator activated receptor gamma gene of Jiulong yak. Chin J Animal Sci 46:6-10
14. Meng H, Li H, Wang YX (2004) Cloning and sequence analysis of cDNA encoding PPAR from goose. Hereditas 26:469-472
15. Schoonjans K, Staels B, Auwerrx J (1996) The peroxisome proliferator-activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochem Biophys Acta 1302:93-109
16. Tontonoz P, Graves RA, Budavari AI, Erdjument-Bromage H, Lui M, Hu E, Tempst P, Spiegelman BM (1994) Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha. Nucleic Acids Res 22:5628-5634
17. Torra IP, Fruchart JC, Staels B (2000) PPARs and atherosclerosis. International Symposium on Lipoprotein Metabolism and Atherogenesis. Springer, Tokyo, pp 88-95
18. Zhu Y, Alvares K, Huang Q, Rao MS, Reddy JK (1993) Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J Biol Chem 268:26817-26820