Berberine inhibited radioresistant effects and enhanced anti-tumor effects in the irradiated-human prostate cancer cells

Toxicological Research

Volumn 26, Issue 2, 2013, Pages 109-115

  Hur, Jung Mu ^a   Kim, Dongho ^b  

^a Chong Kun Dang Healthcare Corp Research Center   (South Korea)

^b Korea Atomic Energy Research Institute   (South Korea)

Author keywords

Apoptosis; Berberine; Radiation; Radioresistant

Indexed keywords

EID: 84880579191     PISSN: 19768257     EISSN: 22342753     Source Type: Journal    
DOI: 10.5487/TR.2010.26.2.109     Document Type: Article

References (28)

1. Baldwin, A.S. (1996). The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol., 14, 649- 683.
2. Bergman, P.J. and Harris, D. (1997). Radioresistance, chemoresistance, and apoptosis resistance. The past, resent, and future. Vet. Clin. N. Am-Small., 27, 47-57.
3. Blumenstein, M., Hossfeld, D.K. and Duhrsen, U. (1998). Indirect radiation leukemogenesis in DBA/2 mice: increased expression of B2 repeats in FDC-P1 cells transformed by intracisternal Aparticle transposition. Ann. Hematol., 76, 53-60.
4. Bohnke, A., Westphal, F., Schmidt, A., El-Awady, R.A. and Dahm-Daphi, J. (2004). Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumor cells. Int. J. Radiat. Biol., 80, 53-63.
5. Bohnke, A., Westphal, F., Schmidt, A., El-Awady, R.A. and Dahm-Daphi, J. (2004). Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumor cells. Int. J. Radiat. Biol., 80, 53-63.
6. Bristow, R., Benchimol, S. and Hill, R. (1996). The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiother. Oncol., 40, 197-223.
7. Bristow, R., Benchimol, S. and Hill, R. (1996). The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiother. Oncol., 40, 197-223.
8. Carson, C.C. (2006). Carcinoma of the prostate: overview of the most common malignancy in men. N. C. Med. J., 67, 122-126.
9. Colombo, R., Naspro, R., Salonia, A., Montorsi, F., Raber, M., Suardi, N., Saccà, A. and Rigatti, P. (2006). Radical prostatectomy after previous prostate surgery: clinical and functional outcomes. J. Urol., 176, 2459-2463.
10. Corbiere, C., Liagre, B., Terro, F. and Beneytout, J.L. (2004). Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells. Cell Res., 14, 188-196.
11. Greenlee, R.T., Murray, T., Bolden, S. and Wingo, P.A. (2000). Cancer statistics. Cancer J. Clinic., 50, 7-33.
12. He, Z.W., Zhao, X.Y., Xu, R.Z. and Wu, D. (2006). Effects of berbamine on growth of leukemia cell line NB4 and its mechanism. Zhejiang Da. Xue. Xue. Bao. Yi. Xue. Ban., 35, 209-214.
13. Hwang, J.M., Kuo, H.C., Tseng, T.H. and Liu, Y.J. (2006). Berberine induces apoptosis through a mitochondria/caspase pathway in human hepatoma cells. Arch. Toxicol., 2, 62-73.
14. Kaminski, J.M., Hanlon, A.L., Joon, D.L., Meistrich, M., Hachem, P. and Pollack, A. (2003). Effect of sequencing of androgen deprivation and radiotherapy on prostate cancer growth. Int. J. Radiat. Oncol. Biol. Phys., 57, 24-28.
15. Keyse, S.M. and Tyrrell, R.M. (1989). Heme oxygenase is the major 32-kDastress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc. Natl. Acad. Sci. USA, 86, 99-103.
16. Kucharczak, J., Simmons, M.J., Fan, Y. and Gelinas, C. (2003). To be, or not to be: NF-kappaB is the answer role of Rel/NF-kappaB in the regulation of apoptosis. Oncogene., 22, 8961-8982.
17. Kuo, C.L., Chi, C.W. and Liu, T.Y. (2004). The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett., 203,127-137.
18. Kuo, C.L., Chi, C.W. and Liu, T.Y. (2005). Modulation of apoptosis by berberine through inhibition of cyclooxygenase-2 and Mcl-1 expression in oral cancer cells. In Vivo., 19, 247-252.
19. Lau, C.W., Yao, X.Q., Chen, Z.Y., Ko, W.H. and Huang, Y. (2001). Cardiovascular actions of berberine. Cardiovasc. Drug Rev., 3, 234-244.
20. Rosser, C.J., Reyes, A.O., Vakar-Lopez, F., Levy, L.B., Kuban, D.A., Hoover, D.C., Lee, A.K. and Pisters, L.L. (2003). Bcl-2 is significantly overexpressed in localized radio-recurrent prostate carcinoma, compared with localized radio-naive prostate carcinoma. Int. J. Radiat. Oncol. Biol. Phys., 56, 1-6.
21. Rosser, C.J., Tanaka, M., Pisters, L.L., Tanaka, N., Levy, L.B., Hoover, D.C., Grossman, H.B., McDonnell, T.J., Kuban, D.A. and Meyn, R.E. (2004). Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation. Cancer Gene Ther., 11, 273-279.
22. Szotowski, B., Antoniak, S., Goldin-Lang, P., Tran, Q.V., Pels, K., Rosenthal, P., Bogdanov, V.Y., Borchert, H.H., Schultheiss, H.P. and Rauch, U. (2007). Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation- and cytokine-induced endothelial cells. Cardiovasc. Res., 73, 806-812.
23. Vink, S.R., Schellens, J.H., Beijnen, J.H., Sindermann, H., Engel, J., Dubbelman, R., Moppi, G., Hillebrand, M.J., Bartelink, H. and Verheij, M. (2006). Phase I and pharmacokinetic study of combined treatment with perifosine and radiation in patients with advanced solid tumours. Radiother. Oncol., 80, 207-213.
24. Wada, T. and Penninger, J.M. (2004). Mitogen-activated protein kinases in apoptosis regulation. Oncogene., 23, 2838-2849.
25. Wang, H.G. and Reed, J.C. (1998). Bc1-2, Raf-1 and mitochondrial regulation of apoptosis. Biofactors., 8, 13-16.
26. Wilson, R.E., Taylor, S.L., Atherton, G.T., Johnston, D., Waters, C.M. and Norton, J.D. (1993). Early response gene signaling cascades activated by ionizing radiation in primary human B cells. Oncogene., 8, 3229-3237.
27. Xia, Z., Dickens, M., Raingeaud, J., Davis, R.J. and Greenberg, M.E. (1995). Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science, 270, 1326-1331.
28. Zhang, Y. and Chen, F. (2004). Reactive oxygen species (ROS), troublemakers between nuclear factor-kappaB (NF-kappaB) and c-Jun NH(2)-terminal kinase (JNK). Cancer Res., 64, 1902- 1905.