-
2
-
-
0029102101
-
Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line
-
Power CA, Meyer A, Nemeth K et al. Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line. J Biol Chem 1995, 270(33): 19495-500.
-
(1995)
J Biol Chem
, vol.270
, Issue.33
, pp. 19495-19500
-
-
Power, C.A.1
Meyer, A.2
Nemeth, K.3
-
3
-
-
0030021091
-
Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4
-
Hoogewerf AJ, Black D, Proudfoot AEI, Wells TNC, Power CA. Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4. Biochem Biophys Res Commun 1996, 218(1): 337-43.
-
(1996)
Biochem Biophys Res Commun
, vol.218
, Issue.1
, pp. 337-343
-
-
Hoogewerf, A.J.1
Black, D.2
Proudfoot, A.E.I.3
Wells, T.N.C.4
Power, C.A.5
-
4
-
-
0029816103
-
Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector
-
Imai T, Yoshida T, Baba M, Nishimura M, Kakizishi M, Yoshie O. Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector. J Biol Chem 1996, 271(35): 21514-21.
-
(1996)
J Biol Chem
, vol.271
, Issue.35
, pp. 21514-21521
-
-
Imai, T.1
Yoshida, T.2
Baba, M.3
Nishimura, M.4
Kakizishi, M.5
Yoshie, O.6
-
5
-
-
0030987778
-
The T celldirected CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4
-
Imai T, Baba M, Nishimura M, Kakizishi M, Takagi S, Osamu Y. The T celldirected CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J Biol Chem 1997, 272(23): 15036-42.
-
(1997)
J Biol Chem
, vol.272
, Issue.23
, pp. 15036-15042
-
-
Imai, T.1
Baba, M.2
Nishimura, M.3
Kakizishi, M.4
Takagi, S.5
Osamu, Y.6
-
6
-
-
0031893264
-
Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4
-
Imai T, Chantry D, Raport CJ et al. Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. J Biol Chem 1998, 273(3): 1764-8.
-
(1998)
J Biol Chem
, vol.273
, Issue.3
, pp. 1764-1768
-
-
Imai, T.1
Chantry, D.2
Raport, C.J.3
-
7
-
-
28944443160
-
Chemokine-like factor 1 is a functional ligand for CC chemokine receptor 4 (CCR4)
-
Wang Y, Zhang Y, Yang X et al. Chemokine-like factor 1 is a functional ligand for CC chemokine receptor 4 (CCR4). Life Sci 2006, 78(6): 614-21.
-
(2006)
Life Sci
, vol.78
, Issue.6
, pp. 614-621
-
-
Wang, Y.1
Zhang, Y.2
Yang, X.3
-
8
-
-
0035397516
-
Molecular cloning and characterisation of chemokinelike factor 1 (CKLF1) a novel human cytokine with a unique structure and potential chemotactic activity
-
Han, W, lou Y, Tang J et al. Molecular cloning and characterisation of chemokinelike factor 1 (CKLF1) a novel human cytokine with a unique structure and potential chemotactic activity. Biochem J 2001, 357(Pt. 1): 127-35.
-
(2001)
Biochem J
, vol.357
, pp. 127-135
-
-
Han, W.1
Lou, Y.2
Tang, J.3
-
9
-
-
0031963014
-
Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
-
Bonecchi R, Bianchi G, Panina-Bourdignon P et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 1998, 187(1): 129-34.
-
(1998)
J Exp Med
, vol.187
, Issue.1
, pp. 129-134
-
-
Bonecchi, R.1
Bianchi, G.2
Panina-Bourdignon, P.3
-
10
-
-
0035903307
-
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4+ CD25+ regulatory T cells
-
Iellem A, Mariani M, Lang R et al. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4+ CD25+ regulatory T cells. J Exp Med 2001, 194(6): 847-53.
-
(2001)
J Exp Med
, vol.194
, Issue.6
, pp. 847-853
-
-
Iellem, A.1
Mariani, M.2
Lang, R.3
-
11
-
-
0033584358
-
The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
-
Campbell JJ, HaraldsenG, Pan J et al. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature 1999, 400(6746): 776-80.
-
(1999)
Nature
, vol.400
, Issue.6746
, pp. 776-780
-
-
Campbell, J.J.1
Haraldsen, G.2
Pan, J.3
-
12
-
-
0034672366
-
Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets
-
Clemetson KJ, Clemetson JM, Proudfoot AEI, Power CA, Baggiolini M, Wells TNC. Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets. Blood 2000, 96(13): 4046-54.
-
(2000)
Blood
, vol.96
, Issue.13
, pp. 4046-4054
-
-
Clemetson, K.J.1
Clemetson, J.M.2
Proudfoot, A.E.I.3
Power, C.A.4
Baggiolini, M.5
Wells, T.N.C.6
-
13
-
-
0036389804
-
Selective CCL5/RANTES-induced mast cell migration through interactions with chemokine receptors CCR1 and CCR4
-
Juremalm M, Olsson N, Nilsson G. Selective CCL5/RANTES-induced mast cell migration through interactions with chemokine receptors CCR1 and CCR4. Biochem Biophys Res Commun 2002, 297(13): 480-5.
-
(2002)
Biochem Biophys Res Commun
, vol.297
, Issue.13
, pp. 480-485
-
-
Juremalm, M.1
Olsson, N.2
Nilsson, G.3
-
14
-
-
0035863816
-
Expression and regulation of chemokine receptors in human natural killer cells
-
Inngjerdingen M, Damaj B, Maghazachi A. Expression and regulation of chemokine receptors in human natural killer cells. Blood 2001, 97(2): 367-75.
-
(2001)
Blood
, vol.97
, Issue.2
, pp. 367-375
-
-
Inngjerdingen, M.1
Damaj, B.2
Maghazachi, A.3
-
15
-
-
0343396569
-
Differential expression of chemokine receptors on peripheral blood, synovial fluid and synovial tissue monocytes/macrophages in rheumatoid arthritis
-
Katschke KJ, Rottman JB, Ruth JH et al. Differential expression of chemokine receptors on peripheral blood, synovial fluid and synovial tissue monocytes/macrophages in rheumatoid arthritis. Arthritis Rheumatism 2001, 44(5): 1022-32.
-
(2001)
Arthritis Rheumatism
, vol.44
, Issue.5
, pp. 1022-1032
-
-
Katschke, K.J.1
Rottman, J.B.2
Ruth, J.H.3
-
16
-
-
0032908743
-
Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine
-
Imai T, Nagira M, Takagi S et al. Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol 1999, 11(1): 81-8.
-
(1999)
Int Immunol
, vol.11
, Issue.1
, pp. 81-88
-
-
Imai, T.1
Nagira, M.2
Takagi, S.3
-
17
-
-
0037338904
-
The role of T lymphocytes in the pathogenesis of asthma
-
Larche M, Robinson D, Kay AB. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003, 111(3): 450-63.
-
(2003)
J Allergy Clin Immunol
, vol.111
, Issue.3
, pp. 450-463
-
-
Larche, M.1
Robinson, D.2
Kay, A.B.3
-
18
-
-
33748933230
-
CCR4 as a novel molecular target for immunotherapy of cancer
-
Ishida T, Ueda R. CCR4 as a novel molecular target for immunotherapy of cancer. Cancer Sci 2006, 97(11): 1139-46.
-
(2006)
Cancer Sci
, vol.97
, Issue.11
, pp. 1139-1146
-
-
Ishida, T.1
Ueda, R.2
-
19
-
-
70350706772
-
-
WO 2003059893. Jul 24
-
Baxter A, Johnson T, Stocks M, Roberts B, Kindon N (AstraZeneca AB). N-Pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases. WO 2003059893. Jul 24, 2003.
-
(2003)
N-Pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases
-
-
Baxter, A.1
Johnson, T.2
Stocks, M.3
Roberts, B.4
Kindon, N.5
AstraZeneca, A.B.6
-
20
-
-
84925967118
-
-
US 20060004010. January 5
-
Habashita H, Kokubo M, Shibayama S, Tada H, Sagawa K (Ono Pharmaceutical Co., Ltd.) Ccr4 antagonist and medical use thereof. US 20060004010. January 5, 2006.
-
(2006)
Ccr4 antagonist and medical use thereof
-
-
Habashita, H.1
Kokubo, M.2
Shibayama, S.3
Tada, H.4
Sagawa, K.5
-
21
-
-
84925967117
-
Synthesis and biological evaluation of 2,4-diaminoquinazoline derivatives and related compounds as novel CC chemokine receptor 4 (CCR4) antagonists
-
August 19-23, Boston, Abst MEDI 376
-
Kawano N, Kontani T, Masuda N et al. Synthesis and biological evaluation of 2,4-diaminoquinazoline derivatives and related compounds as novel CC chemokine receptor 4 (CCR4) antagonists. 234th ACS Natl Meet (August 19-23, Boston) 2007, Abst MEDI 376.
-
(2007)
234th ACS Natl Meet
-
-
Kawano, N.1
Kontani, T.2
Masuda, N.3
-
22
-
-
33846202995
-
Core exploration in optimization of chemokine receptor CCR4 antagonists
-
Purandare A, Wan H, Somerville J et al. Core exploration in optimization of chemokine receptor CCR4 antagonists. Bioorg Med Chem Lett 2007, 17(3): 679-82.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, Issue.3
, pp. 679-682
-
-
Purandare, A.1
Wan, H.2
Somerville, J.3
-
23
-
-
0034657856
-
A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock
-
Chvatchko Y, Hoogewerf AJ, Meyer A et al. A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock. J Exp Med 2000, 191(10): 1755-63.
-
(2000)
J Exp Med
, vol.191
, Issue.10
, pp. 1755-1763
-
-
Chvatchko, Y.1
Hoogewerf, A.J.2
Meyer, A.3
-
24
-
-
0036316038
-
CCR4 in human allergen-induced late responses in the skin and lung
-
Nouri-Aria KT, Wilson D, Francis JN et al. CCR4 in human allergen-induced late responses in the skin and lung. Eur J Immunol 2002, 32(7): 1933-8.
-
(2002)
Eur J Immunol
, vol.32
, Issue.7
, pp. 1933-1938
-
-
Nouri-Aria, K.T.1
Wilson, D.2
Francis, J.N.3
-
25
-
-
0034988909
-
The CC-chemokine receptors CCR4 and CCR8 identify airway T cells of allergen challenged atopic asthmatics
-
Panina-Boudignon P, Papi A, Mariani M et al. The CC-chemokine receptors CCR4 and CCR8 identify airway T cells of allergen challenged atopic asthmatics. J Clin Invest 2001, 107(11): 1357-64.
-
(2001)
J Clin Invest
, vol.107
, Issue.11
, pp. 1357-1364
-
-
Panina-Boudignon, P.1
Papi, A.2
Mariani, M.3
-
26
-
-
17644383278
-
Serum thymus and activation-regulated chemokine, macrophage-derived chemokine and eotaxin as markers of severity of atopic dermatitis
-
Jahnz-Rozyk K, Targowski T, paluchowska E, Owczarek W, Kucharczyk A. Serum thymus and activation-regulated chemokine, macrophage-derived chemokine and eotaxin as markers of severity of atopic dermatitis. Allergy 2005, 60(5): 685-8.
-
(2005)
Allergy
, vol.60
, Issue.5
, pp. 685-688
-
-
Jahnz-Rozyk, K.1
Targowski, T.2
Paluchowska, E.3
Owczarek, W.4
Kucharczyk, A.5
-
27
-
-
0242539918
-
The monocyte-derived chemokine is released in the bronchoalveolar lavage fluid of steady-state asthmatics
-
Lezcano-Meza D, Negrete-Garcia MC, Dante-Escobedo M, Teran LM. The monocyte-derived chemokine is released in the bronchoalveolar lavage fluid of steady-state asthmatics. Allergy 2003, 58(11): 1125-30.
-
(2003)
Allergy
, vol.58
, Issue.11
, pp. 1125-1130
-
-
Lezcano-Meza, D.1
Negrete-Garcia, M.C.2
Dante-Escobedo, M.3
Teran, L.M.4
-
28
-
-
3042639773
-
CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge
-
Pilette C, Francis JN, Till SJ, Durham SR. CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge. Eur Respir J 2004, 23(6): 876-84.
-
(2004)
Eur Respir J
, vol.23
, Issue.6
, pp. 876-884
-
-
Pilette, C.1
Francis, J.N.2
Till, S.J.3
Durham, S.R.4
-
29
-
-
0036721609
-
Quantitative differences in chemokine receptor engagement generate diversity in integrin-depedent lymphocyte adhesion
-
D'Ambrosio D, Albanesi C, Lang R, Girolomoni G, Sinigaglia F, Laudana C. Quantitative differences in chemokine receptor engagement generate diversity in integrin-depedent lymphocyte adhesion. J Immunol 2002, 169(5): 2303-12.
-
(2002)
J Immunol
, vol.169
, Issue.5
, pp. 2303-2312
-
-
D'Ambrosio, D.1
Albanesi, C.2
Lang, R.3
Girolomoni, G.4
Sinigaglia, F.5
Laudana, C.6
-
30
-
-
0035072806
-
Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue
-
Katou F, Ohtani H, Nakayama T et al. Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue. Am J Pathol 2001, 158(4): 1263-70.
-
(2001)
Am J Pathol
, vol.158
, Issue.4
, pp. 1263-1270
-
-
Katou, F.1
Ohtani, H.2
Nakayama, T.3
-
31
-
-
0037114141
-
Differential chemokine production by myeloid and plasmacytoid dendritic cells
-
Penna G, Vulcano M, Roncari A, Facchetti F, Sozzani S, Adorini L. Differential chemokine production by myeloid and plasmacytoid dendritic cells. J Immunol 2002, 169(12): 6673-6.
-
(2002)
J Immunol
, vol.169
, Issue.12
, pp. 6673-6676
-
-
Penna, G.1
Vulcano, M.2
Roncari, A.3
Facchetti, F.4
Sozzani, S.5
Adorini, L.6
-
32
-
-
0035016379
-
Quantitative analysis of chemokine expression by dendritic cell subsets in vitro and in vivo
-
Vissers JL, Hartgers FC, Lindhout E, Teunissen MBM, Figdor CG, Adema, GJ. Quantitative analysis of chemokine expression by dendritic cell subsets in vitro and in vivo. J Leukocyte Biol 2001, 69(5): 785-93.
-
(2001)
J Leukocyte Biol
, vol.69
, Issue.5
, pp. 785-793
-
-
Vissers, J.L.1
Hartgers, F.C.2
Lindhout, E.3
Teunissen, M.B.M.4
Figdor, C.G.5
Adema, G.J.6
-
33
-
-
0033964866
-
Role of B7-CD28/CTLA-4 costimulation and NF-kappa B in allergen-induced T cell chemotaxis by IL-16 and RANTES
-
Hidi R, Riches V, Al-Ali M et al. Role of B7-CD28/CTLA-4 costimulation and NF-kappa B in allergen-induced T cell chemotaxis by IL-16 and RANTES. J Immunol 2000, 164(1): 412-8.
-
(2000)
J Immunol
, vol.164
, Issue.1
, pp. 412-418
-
-
Hidi, R.1
Riches, V.2
Al-Ali, M.3
-
34
-
-
40849124250
-
An intracellular allosteric site for a specific class of antagonists of the CC chemokine G protein-coupled receptors CCR4 and CCR5
-
Andrews G, Jones C, Wreggett K. An intracellular allosteric site for a specific class of antagonists of the CC chemokine G protein-coupled receptors CCR4 and CCR5. Mol Pharmacol 2008, 73(3): 855-67.
-
(2008)
Mol Pharmacol
, vol.73
, Issue.3
, pp. 855-867
-
-
Andrews, G.1
Jones, C.2
Wreggett, K.3
-
36
-
-
0036672988
-
Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice
-
Schuh JM, Power CA, Proudfoot AE, Kunkel SL, Lukacs NW, Hogaboom CM. Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice. FASEB J 2002, 16(10): 1313-5.
-
(2002)
FASEB J
, vol.16
, Issue.10
, pp. 1313-1315
-
-
Schuh, J.M.1
Power, C.A.2
Proudfoot, A.E.3
Kunkel, S.L.4
Lukacs, N.W.5
Hogaboom, C.M.6
-
37
-
-
42149167724
-
iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity
-
Meyer EH, Wurbel EA, Staton TL et al. iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity. J Immunol 2007, 179(7): 4661-71.
-
(2007)
J Immunol
, vol.179
, Issue.7
, pp. 4661-4671
-
-
Meyer, E.H.1
Wurbel, E.A.2
Staton, T.L.3
-
38
-
-
0033168593
-
Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation
-
Gonzalo JA, Pan Y, Lloyd CM et al. Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation. J Immunol 1999, 163(1): 403-11.
-
(1999)
J Immunol
, vol.163
, Issue.1
, pp. 403-411
-
-
Gonzalo, J.A.1
Pan, Y.2
Lloyd, C.M.3
-
39
-
-
0035253654
-
Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice
-
Kawasaki S, Takizawa H, Yoneyama H et al. Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice. J Immunol 2001, 166(3): 2055-62.
-
(2001)
J Immunol
, vol.166
, Issue.3
, pp. 2055-2062
-
-
Kawasaki, S.1
Takizawa, H.2
Yoneyama, H.3
-
40
-
-
0347361649
-
CCR4 blockade does not inhibit allergic airways inflammation
-
Conroy DM, Jopling LA, Lloyd CM et al. CCR4 blockade does not inhibit allergic airways inflammation. J Leuk Biol 2003, 74: 558-63.
-
(2003)
J Leuk Biol
, vol.74
, pp. 558-563
-
-
Conroy, D.M.1
Jopling, L.A.2
Lloyd, C.M.3
-
41
-
-
0036510382
-
The identification, characterization, and distribution of guinea pig CCR4 and epitope mapping of a blocking antibody
-
Jopling LA, Sabroe I, Andrew DP et al. The identification, characterization, and distribution of guinea pig CCR4 and epitope mapping of a blocking antibody. J Biol Chem 2002; 277(9): 6864-73.
-
(2002)
J Biol Chem
, vol.277
, Issue.9
, pp. 6864-6873
-
-
Jopling, L.A.1
Sabroe, I.2
Andrew, D.P.3
-
42
-
-
84925967115
-
CCR4 Blockade inhibits allergic airway inflammation in a humanized SCID mouse model of asthma
-
May 19-24, San Diego, Abst A583
-
Hammad H et al. CCR4 Blockade inhibits allergic airway inflammation in a humanized SCID mouse model of asthma. 102nd Int Conf Am Thorac Soc (May 19-24, San Diego) 2006, Abst A583.
-
(2006)
102nd Int Conf Am Thorac Soc
-
-
Hammad, H.1
|