Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin

Oncology Reports

Volumn 30, Issue 3, 2013, Pages 1059-1066

  Shou, Liu Mei ^a   Zhang, Qiong Yan ^a   Li, Wei ^a   Xie, Xin ^a   Chen, Kai ^a   Lian, Lian ^a,d   Li, Zhen Yu ^f   Gong, Fei Ran ^a,b,c   Dai, Ke Sheng ^a,b,c   Mao, Yi Xiang ^a   Tao, Min ^a,e  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b Departments of Hematology   (China)

^c Jiangsu Institute of Hematology   (China)

^d Suzhou Xiangcheng People's Hospital   (China)

^e Institute of Clinical Immunology of Jiangsu Province   (China)

^f UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Breast cancer; Cantharidin and norcantharidin; Integrin 2; Platelet; Protein kinase C; Protein phosphatase 2A

Indexed keywords

ALPHA2 INTEGRIN; CANTHARIDIN; NORCANTHARIDIN; PROTEIN KINASE C;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL ADHESION; CELL CLONE; CELL MIGRATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; THROMBOCYTE ADHESION; WOUND HEALING;

APOPTOSIS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOOD PLATELETS; BLOTTING, WESTERN; BREAST NEOPLASMS; CANTHARIDIN; CELL ADHESION; CELL PROLIFERATION; DOWN-REGULATION; ENZYME INHIBITORS; FEMALE; FLOW CYTOMETRY; HUMANS; INTEGRIN ALPHA2; MCF-7 CELLS; PLATELET ADHESIVENESS; PROTEIN KINASE C; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR RELA; WOUND HEALING;

EID: 84880575255     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2601     Document Type: Article

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