ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity

Journal of Biological Chemistry

Volumn 288, Issue 29, 2013, Pages 21367-21375

  Lund, Jacob ^a,b   Olsen, Ole H ^b   Sørensen, Esben S ^c   Stennicke, Henning R ^b   Petersen, Helle H ^b   Overgaard, Michael T ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; DOMAIN STRUCTURE; GLYCOSYLATED; MACROGLOBULIN; METALLO-PROTEASE; PROTEOLYTIC ACTIVITIES; ZINC-BINDING SITES;

BIOCHEMISTRY;

BIOLOGY;

METALLOPROTEINASE; PROTEIN ADAMDEC1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GLYCOSYLATION; HUMAN; HUMAN CELL; LATENT PERIOD; LIGAND BINDING; MACROPHAGE; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ADAM ADAMTS; METALLOPROTEASE; METZINCIN; POST-TRANSLATIONAL MODIFICATION; PROTEIN EVOLUTION; PROTEIN EXPRESSION;

ADAM PROTEINS; BIOCATALYSIS; GLYCOSYLATION; HEK293 CELLS; HUMANS; MUTANT PROTEINS; MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RECOMBINANT PROTEINS; ZINC;

EID: 84880558281     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.474536     Document Type: Article

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