Decreased cognitive function in extended family members from the single late-onset-Alzheimer's-disease pedigree

Journal of the International Neuropsychological Society

Volumn 19, Issue 7, 2013, Pages 809-819

  Zeng, Yan ^a   Chang, Wei ^a   Shu, Chang ^a   Ma, Lina ^a   Huang, Yuanyuan ^a   Wang, Ruoshi ^a   Zhang, Junpeng ^a   Zhu, Changcai ^a   McClintock, Shawn M ^b,c  

^a WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Dementia; Genetics; Geriatric; Memory; Pedigree

Indexed keywords

EID: 84880552752     PISSN: 13556177     EISSN: 14697661     Source Type: Journal    
DOI: 10.1017/S1355617713000581     Document Type: Article

References (76)

1. Alzheimer's Association. (2012). Alzheimer's disease facts and figures. Alzheimer's & Dementia, 8(2), 131-168
2. Albert, M.S. (1996). Cognitive and neurobiologic markers of early Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America, 93(24), 13547-13551
3. Albert, M.S., Moss, M.B., Tanzi, R., & Jones, K. (2001). Preclinical prediction of AD using neuropsychological tests. Journal of the International Neuropsychological Society, 7(5), 631-639
4. American Psychiatric Association (Pub.) (1994). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-Text Revision (DSMIV-TR). Washington, DC: American Psychiatric Press, Inc
5. Backman, L., Jones, S., Berger, A.K., Laukka, E.J., & Small, B.J. (2005). Cognitive impairment in preclinical Alzheimer's disease: A meta-Analysis. Neuropsychology, 19(4), 520-531
6. Backman, L., Small, B.J., & Fratiglioni, L. (2001). Stability of the preclinical episodic memory deficit in Alzheimer's disease. Brain, 124(Pt 1), 96-102
7. Baudic, S., Dalla Barba, G., Thibaudet, M.C., Smagghe, A., Remy, P., & Traykov, L. (2006). Executive function deficits in early Alzheimer's disease and their relations with episodic memory. Archives of Clinical Neuropsychology, 21(1), 15-21
8. Bennett, D.A., Wilson, R.S., Boyle, P.A., Buchman, A.S., & Schneider, J.A. (2012). Relation of neuropathology to cognition in persons without cognitive impairment. Annals of Neurology, 72(4), 599-609
9. Bertram, L., & Tanzi, R.E. (2012). The genetics of Alzheimer's disease. Progress in Molecular Biology and Transitional Science, 107, 79-100
10. Bloss, C.S., Delis, D.C., Salmon, D.P., & Bondi, M.W. (2008). Decreased cognition in children with risk factors for Alzheimer's disease. Biological Psychiatry, 64(10), 904-906
11. Bird, T.D. (2005). Genetic factors in Alzheimer's disease. The New England Journal of Medicine, 352, 862-864
12. Bisiacchi, P.S., Borella, E., Bergamaschi, S., Carretti, B., & Mondini, S. (2008). Interplay between memory and executive functions in normal and pathological aging. Journal of Clinical and Experimental Neuropsychology, 30(6), 723-733
13. Blacker, D., Lee, H., Muzikansky, A., Martin, E.C., Tanzi, R., McArdle, J.J., & Albert, M. (2007). Neuropsychological measures in normal individuals that predict subsequent cognitive decline. Archives of Neurology, 64(6), 862-871
14. Bookheimer, S.Y., Strojwas, M.H., Cohen, M.S., Saunders, A.M., Pericak-Vance, M.A., Mazziotta, J.C., & Small, G.W. (2000). Patterns of brain activation in people at risk for Alzheimer's disease. The New England Journal of Medicine, 343, 450-456
15. Bondi, M.W., Jak, A.J., Delano-Wood, L., Jacobson, M.W., Delis, D.C., & Salmon, D.P. (2008). Neuropsychological contributions to the early identification of Alzheimer's disease. Neuropsychology Review, 18(1), 73-90
16. Bondi, M.W., Salmon, D.P., Galasko, D., Thomas, R.G., & Thal, L.J. (1999). Neuropsychological function and Apolipoprotein E genotype in the preclinical detection of Alzheimer's disease. Psychology and Aging, 14(2), 295-303
17. Bondi, M.W., Salmon, D.P., Monsch, A.U., Galasko, D., Butters, N., Klauber, M.R., & Saitoh, T. (1995). Episodic memory changes are associated with the APOE-epsilon 4 allele in nondemented older adults. Neurology, 45(12), 2203-2206
18. Bowie, C.R., & Harvey, P.D. (2006). Administration and interpretation of the trail making test. Nature Protocols, 1(5), 2277-2281
19. Braak, E., Arai, K., & Braak, H. (1999). Cerebellar involvement in Pick's disease: Affliction of mossy fibers, monodendritic brush cells, and dentate projection neurons. Experimental Neurology, 159, 153-163
20. Braak, H., & Braak, E. (1991). Neuropathological staging of Alzheimer-related changes. Acta Neuropathologica (Berl), 82, 239-259
21. Braak, H., & Braak, E. (1996a). Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis. Acta Neuropathologica (Berl), 92, 197-201
22. Braak, H., & Braak, E. (1996b). Evolution of the neuropathology of Alzheimer's disease. Acta Neurologica Scandinavica Supplementary, 165, 3-12
23. Chen, P.J., Ratcliff, G., Belle, S.H., Cauley, J.A., DeKosky, S.T., & Ganguli, M. (2001). Patterns of cognitive decline in presymptomatic Alzheimer disease: A prospective community study. Archives of General Psychiatry, 58(9), 853-858
24. Chiu, H.F., Lee, H.C., Chung, W.S., & Kwong, P.K. (1994). Reliability and validity of the Cantonese version of the Mini-Mental State Examination-A preliminary study. Journal of Hong Kong College of Psychiatrists, 2(5), 25-28
25. Chu, L.W., Chiu, K.C., Hui, S.L., Yu, G.K., Tsui, W.J., & Lee, P.W. (2000). The reliability and validity of the Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog) among the elderly Chinese in Hong Kong. Annals Academy of Medicine Singapore, 29(4), 474-485
26. Communiqué of the National Bureau of Statistics of People's Republic of China on Major Figures of the 2010 Population Census (No. 1) (2011, April 28). National Bureau of Statistics of China. Retrieved from http://www.stats.gov.cn/english/newsandcomingevents/t20110428-402722244.htm
27. Corder, E.H., Saunders, A.M., Strittmatter, W.J., Schmechel, D.E., Gaskell, P.C. Jr., & Rimmler, J.B. (1995). Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology, 45, 1323-1328
28. Dickerson, B.C., Sperling, R.A., Hyman, B.T., Albert, M.S., & Blacker, D. (2007). Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment. Archives of General Psychiatry, 64(12), 1443-1450
29. Donix, M., Ercoli, L.M., Siddarth, P., Brown, J.A., Martin-Harris, L., Burggren, A.C., &Bookheimer, S.Y. (2012). Influence of Alzheimer disease family history and genetic risk on cognitive performance in healthymiddle-Aged and older people. The American Journal of Geriatric Psychiatry, 20(7), 565-573
30. Farrer, L.A., Cupples, L.A., Haines, J.L., Hyman, B., Kukull, W.A., & Mayeux, R. (1997). Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-Analysis. APOE and Alzheimer Disease Meta Analysis Consortium. Journal of the AmericanMedical Association, 278(16), 1349-1356
31. Fine, E.M., Delis, D.C., Wetter, S.R., Jacobson, M.W., Jak, A.J., McDonald, C.R., & Bondi, M.W. (2008). Cognitive discrepancies versus APOE genotype as predictors of cognitive decline in normal-functioning elderly individuals: A longitudinal study. American Journal of Geriatric Psychiatry, 16(5), 366-374
32. Folstein, M.F., Folstein, S.E., & McHugh, P.R., ''Mini-mental state''. (1975). A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189-198
33. Gatz, M., Pedersen, N.L., Berg, S., Johansson, B., Johansson, K., Mortimer, J.A., & Ahlbom, A. (1997). Heritability for Alzheimer's disease: The study of dementia in Swedish twins. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 52(2), M117-M125
34. Gatz, M., Reynolds, C.A., Fratiglioni, L., Johansson, B., Mortimer, J.A., Berg, S., & Pedersen, N.L. (2006). Role of genes and environments for explaining Alzheimer disease. Archives of General Psychiatry, 63(2), 168-174
35. Gladsjo, J.A., Schuman, C.C., Evans, J.D., Peary, G.M., Miller, S.W., & Heaton, R.K. (1999). Norms for letter and category fluency: Demographic corrections for age, education, and ethnicity. Assessment, 6(2), 147-178
36. Green, R.C., Cupples, L.A., Go, R., Benke, K.S., Edeki, T., & Griffith, P.A., y MIRAGE Study Group. (2002). Risk of dementia among white and African American relatives of patients with Alzheimer disease. Journal of the American Medical Association, 287(3), 329-336
37. Goate, A., Chartier-Harlin, M.C., Mullan, M., Brown, J., Crawford, F., Fidani, L., & James, L. (1991). Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature, 349(6311), 704-706
38. Huang, W., Qiu, C., von Strauss, E., Winblad, B., & Fratiglioni, L. (2004). APOE genotype, family history of dementia, and Alzheimer disease risk: A 6-year follow-up study. Archives of Neurology, 61(12), 1930-1934
39. Hughes, C.P., Berg, L., Danziger, W.L., Coben, L.A., & Martin, R.L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140, 566-572
40. Jack, C.R. Jr., Petersen, R.C., Xu, Y., O'Brien, P.C., Smith, G.E., Ivnik, R.J., & Kokmen, E. (2000). Rates of hip-pocampal atrophy correlate with change in clinical status in aging and AD. Neurology, 55(4), 484-489
41. Johnson, D.K., Storandt, M., Morris, J.C., & Galvin, J.E. (2009). Longitudinal study of the transition from healthy aging to Alzheimer disease. Archives of Neurology, 66(10), 1254-1259
42. Johnson, S.C., Schmitz, T.W., Trivedi, M.A., Ries, M.L., Torgerson, B.M., Carlsson, C.M., & Sager, M.A. (2006). The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation. Journal of Neuroscience, 26(22), 6069-6076
43. Kawas, C.H., Corrada, M.M., Brookmeyer, R., Morrison, A., Resnick, S.M., Zonderman, A.B., & Arenberg, D. (2003). Visual memory predicts Alzheimer's disease more than a decade before diagnosis. Neurology, 60(7), 1089-1093
44. Lange, K.L., Bondi, M.W., Galasko, D.G., Delis, D.C., Salmon, D.P., & Thal, L.J. (2002). Decline in verbal memory during preclinical Alzheimer's disease: Examination of the effect of Apolipoprotein E genotype. Journal of the International Neuropsychological Society, 8(7), 943-955
45. Lee, J.H., Cheng, R., Graff-Radford, N., Foroud, T., & Mayeux, R., & National Institute on Aging Late-Onset Alzheimer's Disease Family Study Group. (2008). Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: Implication of additional loci. Archives of Neurology, 65(11), 1518-1526
46. Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D.M., Oshima, J., Pettingell, W.H., & Wang, K. (1995). Candidate gene for the chromosome 1 familial Alzheimer's; disease locus. Science, 269(5266), 973-977
47. Lindeboom, J., & Weinstein, H. (2004). Neuropsychology of cognitive ageing, minimal cognitive impairment, Alzheimer's disease, a vascular cognitive impairment. European Journal of Pharmacology, 490(1-3), 83-86
48. Marshall, G.A., Rentz, D.M., Frey, M.T., Locascio, J.J., Johnson, K.A., & Sperling, R.A. (2011). Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease. Alzheimer's Disease Neuroimaging Initiative. Alzheimers & Dementia, 7(3), 300-308
49. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E.M. (1984). Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology, 34(7), 939-944
50. Morris, J.C., Heyman, A., Mohs, R.C., Hughes, J.P., van Belle, G., Fillenbaum, G., & Clark, C. (1989). The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology, 39(9), 1159-1165
51. Nair, A.K., Gavett, B.E., Damman, M., Dekker, W., Green, R.C., Mandel, A., & Stern, R.A. (2010). Clock drawing test ratings by dementia specialists: Interrater reliability and diagnostic accuracy. The Journal of Neuropsychiatry and Clinical Neuroscience, 22(1), 85-92
52. Perrin, R.J., Fagan, A.M., & Holtzman, D.M. (2009). Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. Nature, 461(7266), 916-922
53. Quental, N.B.M., Brucki, S.M.D., & Bueno, O.F.A. (2009). Visuospatial function in early Alzheimer's disease. Dementia & Neuropsychologia, 3(3), 234-240
54. Reitz, C., Brayne, C., & Mayeux, R. (2011). Epidemiology of Alzheimer disease. Nature Review Neurology, 7(3), 137-152
55. Salmon, D.P., & Bondi, M.W. (2009). Neuropsychological assessment of dementia. Annual Review of Psychology, 60, 257-282
56. Saunders, A.M. (2000). Apolipoprotein E and Alzheimer disease: An update on genetic and functional analyses. Journal of Neuropathology Experimental Neurology, 59(9), 751-758
57. Sherrington, R., Rogaev, E.I., Liang, Y., Rogaeva, E.A., Levesque, G., Ikeda, M., & St George-Hyslop, P.H. (1995). Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature, 375(6534), 754-760
58. Small, B.J., Fratiglioni, L., Viitanen, M., Winblad, B., & Backman, L. (2000). The course of cognitive impairment in preclinical Alzheimer disease: Three-And 6-year follow-up of a population-based sample. Archives of Neurology, 57(6), 839-844
59. Small, G.W., Siddarth, P., Burggren, A.C., Kepe, V., Ercoli, L.M., Miller, K.J., & Barrio, J.R. (2009). Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia. Archives of General Psychiatry, 66(1), 81-87
60. Sosa-Ortiz, A.L., Acosta-Castillo, I., & Prince, M.J. (2012). Epidemiology of dementias and Alzheimer's disease. Archives of Medical Research, 43(8), 600-608
61. Sperling, R.A., Laviolette, P.S., O'Keefe, K., O'Brien, J., Rentz, D.M., Pihlajamaki, M., y Johnson, K.A. (2009). Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron, 63(2), 178-188
62. St. George-Hyslop, P.H., & Petit, A. (2005). Molecular biology and genetics of Alzheimer's disease. Comptes Rendus Biologies, 328(2), 119-130
63. Storandt, M. (2008). Cognitive deficits in the early stages of Alzheimer's disease. Current Directions in Psychological Science, 17(3), 198-202
64. Sweet, R.A., Bennett, D.A., Graff-Radford, N.R., & Mayeux, R., National Institute on Aging Late-Onset Alzheimer's Disease Family Study Group. (2010). Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study. Brain, 133(Pt4), 1155-1162
65. Trivedi, M.A., Schmitz, T.W., Ries, M.L., Torgerson, B.M., Sager, M.A., Hermann, B.P., & Johnson, S.C. (2006). Reduced hippocampal activation during episodic encoding in middle-Aged individuals at genetic risk of Alzheimer's disease: A cross-sectional study. BMC Medicine, 4, 1-14
66. Tsai, R.C., Lin, K.N., Wang, H.J., & Liu, H.C. (2007). Evaluating the uses of the total score and the domain scores in the cognitive abilities screening instrument, Chinese version (CASI C-2.0): Results of confirmatory factor analysis. International Psychogeriatrics, 19(6), 1051-1063
67. Wechsler, D. (1987). Wechsler memory scale-revised manual. San Antonio: Psychological Corporation
68. Weintraub, S., Wicklund, H.A., & Salmon, D.P. (2012). The Neuropsychological profile of Alzheimer disease. Cold Spring Harbor Perspectives in Medicine, 2(a006171), 1-18
69. Welsh, K.A., Butters, N., Hughes, J., Mohs, R.C., & Heyman, A. (1991). Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures. Archives of Neurology, 48(3), 278-281
70. Welsh, K.A., Butters, N., Hughes, J.P., Mohs, R.C., & Heyman, A. (1992). Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease. Archives of Neurology, 49(5), 448-452
71. Welsh, K.A., Butters, N., Mohs, R.C., Beekly, D., Edland, S., Fillenbaum, G., & Heyman, A. (1994). The Consortium to Establish a Registry for Alzheimer's Disease (CERAD).V. A normative study of the neuropsychological battery. Neurology, 44(4), 609-614
72. Werheid, K., Hoppe, C., Thone, A., Muller, U., Mungersdorf, M., & von Cramon, D.Y. (2002). The Adaptive Digit Ordering Test: Clinical application, reliability, and validity of a verbal working memory test. Archives of Clinical Neuropsychology, 17(6), 547-565
73. Wilson, R.S., Barral, S., Lee, J.H., Leurgans, S.E., Foroud, T.M., Sweet, R.A., & Bennett, D.A. (2011). Heritability of different forms of memory in the Late Onset Alzheimer's Disease Family Study. Journal of Alzheimer's Disease, 23(2), 249-255
74. Wilson, R.S., & Bennett, D.A. (2005). Assessment of cognitive decline in old age with brief tests amenable to telephone administration. Neuroepidemiology, 25(1), 19-25
75. Wilson, R.S., Leurgans, S.E., Foroud, T.M., Sweet, R.A., Graff-Radford, N., Mayeux, R., & Bennett, D.A., National Institute on Aging Late-Onset Alzheimer's Disease Family Study Group. (2010). Assessment of cognitive function in the Late Onset Alzheimer's Disease Family Study. Archives of Neurology, 67(7), 855-861
76. Xu, G., McLaren, D.G., Ries, M.L., Fitzgerald, M.E., Bendlin, B.B., Rowley, H.A.,yJohnson, S.C. (2009). The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory. Brain, 132(Pt 2), 383-391