An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice
K Podsypanina, RT Lee, C Politis et al. An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice Proc Natl Acad Sci U S A 98 2001 10320 10325
Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin- dependent kinase inhibitors
Y Yamamoto-Yamaguchi, J Okabe-Kado, T Kasukabe et al. Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors Exp Hematol 29 2001 582 588
Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin
C Ly, AF Arechiga, JV Melo et al. Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin Cancer Res 63 2003 5716 5722
Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs
MG Mohi, C Boulton, TL Gu et al. Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs PNAS 101 2004 3130 3135
In vitro and in vivo antileukemic effects of the mTOR-targeting drugs rapamycin in patients with imatinib-resistant CML
abstract 4834.
M Mayerhofer, A Boehm, KJ Aichberger et al. In vitro and in vivo antileukemic effects of the mTOR-targeting drugs rapamycin in patients with imatinib-resistant CML Blood 2005 106 abstract 4834.