Complex I inhibition in the visual pathway induces disorganization of the node of Ranvier

Neurobiology of Disease

Volumn 58, Issue , 2013, Pages 281-288

  Marella, Mathieu ^a   Patki, Gaurav ^a   Matsuno Yagi, Akemi ^a   Yagi, Takao ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Mitochondrial complex I; Myelination; Neurodegenerative disease; Node of Ranvier; Optic neuropathy; Visual pathway

Indexed keywords

CELL ADHESION MOLECULE; CONTACTIN; CONTACTIN ASSOCIATED PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CONTROLLED STUDY; DEMYELINATING DISEASE; DEMYELINATION; ENZYME INHIBITION; MITOCHONDRION; MYELINATION; NERVE FIBER; NEUROPATHOLOGY; NONHUMAN; OPTIC NERVE; OPTIC NERVE DISEASE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; RANVIER NODE; RETINA GANGLION CELL; SUPERIOR COLLICULUS; VISUAL IMPAIRMENT; VISUAL SYSTEM;

7,8-DIHYDRO-8-OXO-DEOXYGUANINE; 8-OXO-DG; AAV2-NDI1; ADENO-ASSOCIATED VIRUS CARRYING THE NDI1 GENE; COMPLEX I; INTERNAL ROTENONE-INSENSITIVE NADH-QUINONE OXIDOREDUCTASE OF SACCHAROMYCES CEREVISIAE MITOCHONDRIA; MITOCHONDRIAL COMPLEX I; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTON-TRANSLOCATING NADH-QUINONE OXIDOREDUCTASE; MTDNA; MYELINATION; NDI1; NEURODEGENERATIVE DISEASE; NODE OF RANVIER; OPTIC NEUROPATHY; REACTIVE OXYGEN SPECIES; RETINAL GANGLION CELL; RGC; ROS; SC; SUPERIOR COLLICULUS; VC; VISUAL CORTEX; VISUAL PATHWAY;

ANIMALS; CELL ADHESION MOLECULES; CELL ADHESION MOLECULES, NEURONAL; CELL COUNT; CONTACTINS; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT COMPLEX I; INSECTICIDES; MALE; MYELIN PROTEINS; NERVE TISSUE PROTEINS; OPTIC NERVE; RANVIER'S NODES; RATS; RATS, LONG-EVANS; REACTIVE OXYGEN SPECIES; ROTENONE; TIME FACTORS; VISUAL PATHWAYS;

EID: 84880436318     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.06.010     Document Type: Article

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