Flotillin-1 promotes cell growth and metastasis in oral squamous cell carcinoma

Neoplasma

Volumn 60, Issue 4, 2013, Pages 395-405

  Xiong, P ^a   Xiao, L Y ^a   Zhao, C C ^b   Yang, R ^a   Guo, Q ^a   Zhao, Y Q ^a   Li, W ^a   Sun, Y ^b  

^a SICHUAN UNIVERSITY   (China)

^b Chengdu Military Region   (China)

Author keywords

Flotillin 1; Metastasis; OSCC; Proliferation

Indexed keywords

BETA ACTIN; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; FLOTILLIN 1; I KAPPA B KINASE ALPHA; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR TWIST; UVOMORULIN; VIMENTIN; FLOTILLINS; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE TRANSLOCATION; HUMAN; HUMAN CELL; METASTASIS; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; TUMOR GROWTH; WESTERN BLOTTING; ZEBRA FISH; ANIMAL; CELL CULTURE; MOUTH TUMOR; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; MEMBRANE PROTEINS; MICE; MOUTH NEOPLASMS; NEOPLASM METASTASIS; NF-KAPPA B; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; ZEBRAFISH;

MLCS; MLOWN;

EID: 84880421030     PISSN: 00282685     EISSN: 13384317     Source Type: Journal    
DOI: 10.4149/neo_2013_051     Document Type: Article

References (42)

1. XIONG P, LI Y, TANG Y, CHEN H. Proteomic Analyses of Sirt1-Mediated Cisplatin Resistance in OSCC Cell Line. The Protein Journal. 2011; 30: 499-508. http://dx.doi.org/10.1007/s10930-011-9354-9
2. LO WL, KAO SY, CHI LY, WONG YK, CHANG R. Outcomes of oral squamous cell carcinoma in Taiwan after surgical therapy: factors affecting survival. Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons. 2003; 61: 751. http://dx.doi.org/10.1016/S0278-2391(03)00149-6
3. SHEU JJC, HUA CH, WAN L, LIN YJ, LAI MT et al. Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma. Cancer research. 2009; 69: 2568-76. http://dx.doi.org/10.1158/0008-5472.CAN-08-3199
4. CHIOU SH, YU CC, HUANG CY, LIN SC, LIU CJ et al. Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma. Clinical Cancer Research. 2008; 14: 4085-95. http://dx.doi.org/10.1158/1078-0432.CCR-07-4404
5. REIS PP, TOMENSON M, CERVIGNE NK, MACHADO J, JURISICA I et al. Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma. Molecular cancer. 2010; 9: 238. http://dx.doi.org/10.1186/1476-4598-9-238
6. NAGARAJ NS. Evolving 'omics' technologies for diagnostics of head and neck cancer. Briefings in functional genomics & proteomics. 2009; 8: 49-59. http://dx.doi.org/10.1093/bfgp/elp004
7. LIN SC, CHEN YJ, KAO SY, HSU MT, LIN CH et al. Chromosomal changes in betel-associated oral squamous cell carcinomas and their relationship to clinical parameters. Oral oncology. 2002; 38: 266-73. http://dx.doi.org/10.1016/S1368-8375(01)00054-9
8. NAGPAL JK, PATNAIK S, DAS BR. Prevalence of high-risk human papilloma virus types and its association with P53 codon 72 polymorphism in tobacco addicted oral squamous cell carcinoma (OSCC) patients of Eastern India. International journal of cancer. 2001; 97: 649-53. http://dx.doi.org/10.1002/ijc.10112
9. SARTOR M, STEINGRIMSDOTTIR H, ELAMIN F, GAKEN J, WARNAKULASURIYA S et al. Role of p16/MTS1, cyclin D1 and RB in primary oral cancer and oral cancer cell lines. British journal of cancer. 1999; 80: 79. http://dx.doi.org/10.1038/sj.bjc.6690505
10. PETRICOIN EF, ZOON KC, KOHN EC, BARRETT JC, LIOTTA LA. Clinical proteomics: translating benchside promise into bedside reality. Nature Reviews Drug Discovery. 2002; 1: 683-95. http://dx.doi.org/10.1038/nrd891
11. RIENTO K, FRICK M, SCHAFER I, NICHOLS BJ. Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase. Journal of cell science. 2009; 122: 912-8. http://dx.doi.org/10.1242/jcs.039024
12. LIU J, DEYOUNG SM, ZHANG M, DOLD LH, SALTIEL AR. The stomatin/prohibitin/flotillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1 adipocytes. Journal of Biological Chemistry. 2005; 280: 16125-34. http://dx.doi.org/10.1074/jbc.M500940200
13. SALZER U, PROHASKA R. Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts. Blood. 2001; 97: 1141-3. http://dx.doi.org/10.1182/blood.V97.4.1141
14. THIEN CBF, LANGDON WY. Cbl: many adaptations to regulate protein tyrosine kinases. Nature Reviews Molecular Cell Biology. 2001; 2: 294-307. http://dx.doi.org/10.1038/35067100
15. BAUMANN CA, RIBON V, KANZAKI M, THURMOND DC, MORA S et al. CAP defines a second signalling pathway required for insulin-stimulated glucose transport. 2000.
16. SONG L, GONG H, LIN C, WANG C, LIU L, WU J, et al. Flotillin-1 Promotes Tumor Necrosis Factor-α Receptor Signaling and Activation of NF-κB in Esophageal Squamous Cell Carcinoma Cells. Gastroenterology. 2012. http://dx.doi.org/10.1053/j.gastro.2012.06.033
17. ZHANG PF, ZENG GQ, HU R, LI C, YI H et al. Identification of Flotillin-1 as a novel biomarker for lymph node metastasis and prognosis of lung adenocarcinoma by quantitative plasma membrane proteome analysis. Journal of Proteomics. 2012. http://dx.doi.org/10.1016/j.jprot.2012.08.021
18. LIN C, WU Z, LIN X, YU C, SHI T et al. Knockdown of FLOT1 impairs cell proliferation and tumorigenicity in breast cancer through upregulation of FOXO3a. Clinical Cancer Research. 2011; 17: 3089-99. http://dx.doi.org/10.1158/1078-0432.CCR-10-3068
19. KRISANAPRAKORNKIT S, WEINBERG A, PEREZ CN, DALE BA. Expression of the peptide antibiotic human β-defensin 1 in cultured gingival epithelial cells and gingival tissue. Infection and immunity. 1998; 66: 4222-8.
20. ZHOU X, LI X, GOU M, QIU J, LI J et al. Antitumoral efficacy by systemic delivery of heparin conjugated polyethylenimine-plasmid interleukin-15 complexes in murine models of lung metastasis. Cancer science. 2011; 102: 1403-9. http://dx.doi.org/10.1111/j.1349-7006.2011.01956.x
21. LEE SLC, ROUHI P, JENSEN LD, ZHANG D, JI H, HAUPTMANN G, et al. Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model. Proceedings of the National Academy of Sciences. 2009; 106: 19485-90. http://dx.doi.org/10.1073/pnas.0909228106
22. HUBER MA, KRAUT N, BEUG H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Current opinion in cell biology. 2005; 17: 548-58. http://dx.doi.org/10.1016/j.ceb.2005.08.001
23. JOYCE D, BOUZAHZAH B, FU M, ALBANESE C, D'AMICO M et al. Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-κB-dependent pathway. Journal of Biological Chemistry. 1999; 274: 25245-9. http://dx.doi.org/10.1074/jbc.274.36.25245
24. FRANCO HL, CASASNOVAS J, RODRIGUEZ-MEDINA JR, CADILLA CL. Redundant or separate entities?-roles of Twist1 and Twist2 as molecular switches during gene transcription. Nucleic acids research. 2011; 39: 1177-86. http://dx.doi.org/10.1093/nar/gkq890
25. LE PAGE C, KOUMAKPAYI IH, LESSARD L, MES-MASSON AM, SAAD F. EGFR and Her-2 regulate the constitutive activation of NF-kappaB in PC-3 prostate cancer cells. The Prostate. 2005; 65: 130-40. http://dx.doi.org/10.1002/pros.20234
26. AMADDII M, MEISTER M, BANNING A, TOMASOVIC A, MOOZ J et al. Flotillin-1/Reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling. Journal of Biological Chemistry. 2012; 287: 7265-78. http://dx.doi.org/10.1074/jbc.M111.287599
27. ZHU XF, LIU ZC, XIE BF, LI ZM, FENG GK et al. EGFR tyrosine kinase inhibitor AG1478 inhibits cell proliferation and arrests cell cycle in nasopharyngeal carcinoma cells. Cancer letters. 2001; 169: 27-32. http://dx.doi.org/10.1016/S0304-3835(01)00547-X
28. CLARK CA, MCEACHERN MD, SHAH SH, RONG Y, RONG X, et al. Curcumin inhibits carcinogen and nicotine-induced mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma. Cancer Prevention Research. 2010; 3: 1586-95. http://dx.doi.org/10.1158/1940-6207.CAPR-09-0244
29. JIMI E, FURUTA H, MATSUO K, TOMINAGA K, TAKAHASHI T et al. The cellular and molecular mechanisms of bone invasion by oral squamous cell carcinoma. Oral diseases. 2011; 17: 462-8. http://dx.doi.org/10.1111/j.1601-0825.2010.01781.x
30. MCMAHON HT, GALLOP JL. Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature. 2005; 438: 590-6. http://dx.doi.org/10.1038/nature04396
31. HANCOCK JF. Lipid rafts: contentious only from simplistic standpoints. Nature Reviews Molecular Cell Biology. 2006; 7: 456-62. http://dx.doi.org/10.1038/nrm1925
32. BICKEL PE, SCHERER PE, SCHNITZER JE, OH P, LISANTI MP et al. Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. Journal of Biological Chemistry. 1997; 272: 13793-802. http://dx.doi.org/10.1074/jbc.272.21.13793
33. SANTAMARIA A, CASTELLANOS E, GOMEZ V, BENEDIT P, RENAU-PIQUERAS et al. PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts. Molecular and cellular biology. 2005; 25: 1900-11. http://dx.doi.org/10.1128/MCB.25.5.1900-1911.2005
34. KIM BY, GAYNOR RB, SONG K, DRITSCHILO A, JUNG M. Constitutive activation of NF-kappaB in Ki-ras-transformed prostate epithelial cells. Oncogene. 2002; 21:4490. http://dx.doi.org/10.1038/sj.onc.1205547
35. HAMMERMAN PS, FOX CJ, CINALLI RM, XU A, WAGNER JD et al. Lymphocyte transformation by Pim-2 is dependent on nuclear factor-κB activation. Cancer research. 2004; 64: 8341-8. http://dx.doi.org/10.1158/0008-5472.CAN-04-2284
36. HANSON JL, HAWKE NA, KASHATUS D, BALDWIN AS. The nuclear factor κB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation. Cancer research. 2004; 64: 7248-55. http://dx.doi.org/10.1158/0008-5472.CAN-03-3898
37. ANTO RJ, MUKHOPADHYAY A, SHISHODIA S, GAIROLA CG, AGGARWAL BB. Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: correlation with induction of cyclooxygenase-2. Carcinogenesis. 2002; 23: 1511-8. http://dx.doi.org/10.1093/carcin/23.9.1511
38. AGGARWAL BB. Signalling pathways of the TNF superfamily: a double-edged sword. Nature Reviews Immunology. 2003; 3: 745-56. http://dx.doi.org/10.1038/nri1184
39. HUBER MA, BEUG H, WIRTH T. Epithelial-mesenchymal transition: NF-κB takes center stage. Cell Cycle. 2004; 3: 1477-80. http://dx.doi.org/10.4161/cc.3.12.1280
40. YEH CB, HSIEH MJ, HSIEH YH, CHIEN MH, CHIOU HL et al. Antimetastatic Effects of Norcantharidin on Hepatocellular Carcinoma by Transcriptional Inhibition of MMP-9 through Modulation of NF-kB Activity. PloS one. 2012; 7: e31055. http://dx.doi.org/10.1371/journal.pone.0031055
41. JULIEN S, PUIG I, CARETTI E, BONAVENTURE J, NELLES L et al. Activation of NF-κB by Akt upregulates Snail expression and induces epithelium mesenchyme transition. Oncogene. 2007; 26: 7445-56. http://dx.doi.org/10.1038/sj.onc.1210546
42. FELX M, GUYOT M, ISLER M, TURCOTTE R, DOYON J et al. Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-kappaB in human osteosarcoma. Clinical Science. 2006; 110: 645-54. http://dx.doi.org/10.1042/CS20050286