Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production

Blood

Volumn 121, Issue 21, 2013, Pages 4413-4416

  Safdar, Huma ^a   Cheung, Ka Lei ^a   Salvatori, Daniela ^a   Versteeg, Henri H ^a   Laghmani, El Houari ^a   Wagenaar, Gerry T M ^a   Reitsma, Pieter H ^a   Van Vlijmen, Bart J M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; DABIGATRAN ETEXILATE; FIBRIN; FIBRINOGEN; PROTEIN C; SMALL INTERFERING RNA; ANTITHROMBIN III;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD CLOTTING DISORDER; CONTROLLED STUDY; FIBRIN DEPOSITION; FIBRINOGEN BLOOD LEVEL; GENE FUNCTION; GENE SILENCING; MANDIBLE; MAXILLA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA INTERFERENCE; VEIN THROMBOSIS; ACUTE DISEASE; ANIMAL; C57BL MOUSE; DISEASE MODEL; FEMALE; GENETICS; LIVER; PATHOPHYSIOLOGY; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX;

ACUTE DISEASE; ANIMALS; ANTITHROMBIN III; BLOOD COAGULATION DISORDERS; DISEASE MODELS, ANIMAL; FEMALE; GENE SILENCING; LIVER; MICE; MICE, INBRED C57BL; PHENOTYPE; PROTEIN C; RNA, SMALL INTERFERING; SEVERITY OF ILLNESS INDEX; VENOUS THROMBOSIS;

MLCS; MLOWN;

EID: 84880407298     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-11-465674     Document Type: Article

References (6)

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