Modulation of mouse coagulation gene transcription following acute in vivo delivery of synthetic small interfering RNAs targeting HNF4α and C/EBPα

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Safdar, Huma ^a   Cheung, Ka Lei ^a   Vos, Hans L ^a   Gonzalez, Frank J ^b   Reitsma, Pieter H ^a   Inoue, Yusuke ^c   van Vlijmen, Bart J M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NATIONAL CANCER INSTITUTE   (United States)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ANTIPLASMIN; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 9; CCAAT ENHANCER BINDING PROTEIN ALPHA; FATTY ACID BINDING PROTEIN; FIBRINOGEN; FIBRINOGEN A; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, MOUSE; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; COAGULATION GENE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE CONTROL; GENE SILENCING; GENE TARGETING; HEPATIC GENE; IN VIVO STUDY; MOUSE; NONHUMAN; REDUCTION; TRANSCRIPTION REGULATION; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; CELL CULTURE; FEMALE; GENE EXPRESSION REGULATION; GENE TRANSFER; GENETIC TRANSCRIPTION; GENETICS; LIVER; LIVER CELL; METABOLISM; REPRODUCIBILITY;

ANIMALIA;

ANIMALS; BLOOD COAGULATION; CCAAT-ENHANCER-BINDING PROTEINS; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GENE TARGETING; GENE TRANSFER TECHNIQUES; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; LIVER; MICE; MICE, INBRED C57BL; ORGAN SPECIFICITY; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC;

EID: 84861758209     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038104     Document Type: Article

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