Toxicokinetics of α-thujone following intravenous and gavage administration of α-thujone or α- and β-thujone mixture in male and female F344/N rats and B6C3F1 mice

Toxicology and Applied Pharmacology

Volumn 271, Issue 2, 2013, Pages 216-228

  Waidyanatha, Suramya ^a   Johnson, Jerry D ^b   Hong, S Peter ^b   Robinson, Veronica Godfrey ^a   Gibbs, Seth ^b   Graves, Steven W ^b   Hooth, Michelle J ^a   Smith, Cynthia S ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b BATTELLE MEMORIAL INSTITUTE   (United States)

Author keywords

Bioavailability; Gavage; Neurotoxicity; Rodents; Thujone; Toxicokinetics

Indexed keywords

ABSINTHOL; BETA THUYONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; FEMALE; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; RAT; SEX DIFFERENCE; TOXICOKINETICS;

BIOAVAILABILITY; GAVAGE; NEUROTOXICITY; RODENTS; THUJONE; TOXICOKINETICS;

ALGORITHMS; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; BRAIN CHEMISTRY; CHEMISTRY, PHARMACEUTICAL; DATA INTERPRETATION, STATISTICAL; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HALF-LIFE; INJECTIONS, INTRAVENOUS; INTUBATION, GASTROINTESTINAL; ISOMERISM; MALE; MICE; MICE, INBRED STRAINS; MONOTERPENES; PHARMACOKINETICS; RATS; RATS, INBRED F344;

EID: 84880397126     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.05.001     Document Type: Article

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