Resveratrol-based combinatorial strategies for cancer management

Annals of the New York Academy of Sciences

Volumn 1290, Issue 1, 2013, Pages 113-121

  Singh, Chandra K ^a   George, Jasmine ^a   Ahmad, Nihal ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Cancer; Chemoprevention; Combination chemoprevention; Resveratrol

Indexed keywords

APIGENIN; BAICALEIN; CATECHIN; CURCUMIN; DOXORUBICIN; GEFITINIB; GENISTEIN; MELATONIN; PIPERINE; POLYPHENOL; QUERCETIN; RESVERATROL; TEMOZOLOMIDE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BIOAVAILABILITY; BREAST CANCER; CANCER CHEMOTHERAPY; CHEMOPROPHYLAXIS; DRUG EFFICACY; GLIOMA; HUMAN; LUNG CANCER; MELANOMA; NONHUMAN; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; RESTENOSIS; SKIN CANCER; SKIN CARCINOGENESIS; UNSPECIFIED SIDE EFFECT;

EID: 84880354207     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/nyas.12160     Document Type: Article

References (50)

1. Sporn, M.B. et al. 1976. Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed. Proc. 35: 1332-1338.
2. Yuan, Y. et al. 2012. Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway. CNS Neurosci. Ther. 18: 536-546.
3. Iwuchukwu, O.F., R.J. Tallarida & S. Nagar. 2011. Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells. Life Sci. 88: 1047-1054.
4. Harper, C.E. et al. 2009. Genistein and resveratrol, alone and in combination, suppress prostate cancer in SV-40 tag rats. Prostate 69: 1668-1682.
5. Tak, J.K., J.H. Lee & J.W. Park. 2012. Resveratrol and piperine enhance radiosensitivity of tumor cells. BMB Rep. 45: 242-246.
6. Kiskova, T. et al. 2012. A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Eur. J. Cancer Prev. 21: 163-170.
7. George, J. et al. 2011. Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53. PLoS One 6: e23395.
8. Castillo-Pichardo, L. & S.F. Dharmawardhane. 2012. Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer. Nutr. Cancer. 64: 1058-1069.
9. Harikumar, K.B. & B.B. Aggarwal. 2008. Resveratrol: a multitargeted agent for age-associated chronic diseases. Cell Cycle 7: 1020-1035.
10. Paul, B. et al. 1999. Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India. J. Ethnopharmacol. 68: 71-76.
11. Timmers, S., J. Auwerx & P. Schrauwen. 2012. The journey of resveratrol from yeast to human. Aging 4: 146-158.
12. Yang, F., T. Zhang & Y. Ito. 2001. Large-scale separation of resveratrol, anthraglycoside A and anthraglycoside B from Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography. J. Chromatogr. A 919: 443-448.
13. Jang, M. et al. 1997. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275: 218-220.
14. Harper, C.E. et al. 2007. Resveratrol suppresses prostate cancer progression in transgenic mice. Carcinogenesis 28: 1946-1953.
15. Seeni, A. et al. 2008. Suppression of prostate cancer growth by resveratrol in the transgenic rat for adenocarcinoma of prostate (TRAP) model. Asian Pac. J. Cancer Prev. 9: 7-14.
16. Ndiaye, M. et al. 2011. The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges. Arch. Biochem. Biophys. 508: 164-170.
17. Aziz, M.H. et al. 2005. Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? FASEB J. 19: 1193-1195.
18. Bhattacharya, S., S.R. Darjatmoko & A.S. Polans. 2011. Resveratrol modulates the malignant properties of cutaneous melanoma through changes in the activation and attenuation of the antiapoptotic protooncogenic protein Akt/PKB. Melanoma. Res. 21: 180-187.
19. Lee, H.S., A.W. Ha & W.K. Kim. 2012. Effect of resveratrol on the metastasis of 4T1 mouse breast cancer cells in vitro and in vivo. Nutr. Res. Pract. 6: 294-300.
20. Atten, M.J. et al. 2005. Resveratrol regulates cellular PKC alpha and delta to inhibit growth and induce apoptosis in gastric cancer cells. Invest. N. Drugs 23: 111-119.
21. Huderson, A.C. et al. 2012. Chemoprevention of benzo(a)pyrene-induced colon polyps in Apc(Min) mice by resveratrol. J. Nutr. Biochem. 24: 713-724.
22. Juan, M.E., I. Alfaras & J.M. Planas. 2012. Colorectal cancer chemoprevention by trans-resveratrol. Pharmacol. Res. 65: 584-591.
23. Patel, K.R. et al. 2010. Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients. Cancer Res. 70: 7392-7399.
24. Athar, M. et al. 2007. Resveratrol: a review of preclinical studies for human cancer prevention. Toxicol. Appl. Pharmacol. 224: 274-283.
25. Malhotra, A., P. Nair & D.K. Dhawan. 2011. Curcumin and resveratrol synergistically stimulate p21 and regulate cox-2 by maintaining adequate zinc levels during lung carcinogenesis. Eur. J. Cancer Prev. 20: 411-416.
26. Howells, L.M. et al. 2011. Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases-safety, pharmacokinetics, and pharmacodynamics. Cancer Prev. Res. 4: 1419-1425.
27. Vang, O. et al. 2011. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One 6: e19881.
28. Patel, K.R. et al. 2011. Clinical trials of resveratrol. Ann. N.Y. Acad. Sci. 1215: 161-169.
29. Garodia, P. et al. 2007. From ancient medicine to modern medicine: ayurvedic concepts of health and their role in inflammation and cancer. J. Soc. Integr. Oncol. 5: 25-37.
30. Wang, Z. et al. 2012. Emerging glycolysis targeting and drug discovery from chinese medicine in cancer therapy. Evid. Based Compl. Alternat. Med. 2012: 873175.
31. Ouyang, H. et al. 2011. Multimodality treatment of pancreatic cancer with liver metastases using chemotherapy, radiation therapy, and/or Chinese herbal medicine. Pancreas 40: 120-125.
32. DeVita, V.T., Jr. & E. Chu. 2008. A history of cancer chemotherapy. Cancer Res. 68: 8643-8653.
33. Ndiaye, M., R. Kumar & N. Ahmad. 2011. Resveratrol in cancer management: where are we and where we go from here? Ann. N.Y. Acad. Sci. 1215: 144-149.
34. Johnson, J.J. et al. 2011. Enhancing the bioavailability of resveratrol by combining it with piperine. Mol. Nutr. Food Res. 55: 1169-1176.
35. Lambert, J.D. et al. 2004. Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice. J. Nutr. 134: 1948-1952.
36. Khandelwal, A.R. et al. 2012. Resveratrol and quercetin interact to inhibit neointimal hyperplasia in mice with a carotid injury. J. Nutr. 142: 1487-1494.
37. Zhou, M. et al. 2012. Transcriptomic and metabonomic profiling reveal synergistic effects of quercetin and resveratrol supplementation in high fat diet fed mice. J. Proteome Res. 11: 4961-4971.
38. De Santi, C. et al. 2000. Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids. Xenobiotica 30: 857-866.
39. Kwon, K.J. et al. 2011. Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: a possible role in neuroprotection. J. Pineal. Res. 50: 110-123.
40. Zhang, J.J. et al. 2009. Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells. Am. J. Physiol. Cell Physiol. 297: C632-644.
41. Slusarz, A. et al. 2010. Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer. Cancer Res. 70: 3382-3390.
42. Jiang, J. et al. 2012. ProstaCaid inhibits tumor growth in a xenograft model of human prostate cancer. Int. J. Oncol. 40: 1339-1344.
43. Fulda, S. & K.M. Debatin. 2004. Sensitization for anticancer drug-induced apoptosis by the chemopreventive agent resveratrol. Oncogene 23: 6702-6711.
44. Gupta, S.C. et al. 2011. Chemosensitization of tumors by resveratrol. Ann. N.Y. Acad. Sci. 1215: 150-160.
45. Lin, C.J. et al. 2012. Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy. Free Radic. Biol. Med. 52: 377-391.
46. Gatouillat, G. et al. 2010. Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma. J. Cell Biochem. 110: 893-902.
47. Fukui, M., N. Yamabe & B.T. Zhu. 2010. Resveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo. Eur. J. Cancer. 46: 1882-1891.
48. Ghanim, H. et al. 2010. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J. Clin. Endocrinol. Metab. 95: E1-8.
49. Nguyen, A.V. et al. 2009. Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer. Cancer Manag. Res. 1: 25-37.
50. Ortuno, J. et al. 2010. Matrix effects on the bioavailability of resveratrol in humans. Food Chem. 120: 1123-1130.