Combination of siRNA-directed gene silencing with cisplatin reverses drug resistance in human non-small cell lung cancer

Molecular Therapy Nucleic Acids

Volumn 2, Issue , 2013, Pages e110-

  Ganesh, Shanthi ^a,b   Iyer, Arun K ^a   Weiler, Jan ^b   Morrissey, David V ^b   Amiji, Mansoor M ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Cisplatin resistance; Combination therapy; Lung cancer; Multidrug resistance; Nanoparticles; SiRNA delivery

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CISPLATIN; DOXORUBICIN; LACTATE DEHYDROGENASE; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BCL 2; SMALL INTERFERING RNA; SURVIVIN; HYALURONIC ACID; LIVER ENZYME;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALGORITHM; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CANCER INHIBITION; CANCER RESISTANCE; DOWN REGULATION; DRUG SAFETY; DRUG TOLERABILITY; FOLLOW UP; GENE EXPRESSION; GENE SILENCING; HYDRODYNAMICS; IC 50; IN VITRO STUDY; IN VIVO STUDY; LACTATE DEHYDROGENASE BLOOD LEVEL; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR VOLUME; WEIGHT REDUCTION; ZETA POTENTIAL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; BODY WEIGHT; CANCER COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; ENCAPSULATION; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIVER; SPLEEN;

EID: 84880350972     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2013.29     Document Type: Article

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