Functional tight junction barrier localizes in the second layer of the stratum granulosum of human epidermis

Journal of Dermatological Science

Volumn 71, Issue 2, 2013, Pages 89-99

  Yoshida, Kazue ^a,b   Yokouchi, Mariko ^a,c   Nagao, Keisuke ^a   Ishii, Ken ^a,d   Amagai, Masayuki ^a   Kubo, Akiharu ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^c TOKYO ELECTRIC POWER COMPANY   (Japan)

^d TOHO UNIVERSITY   (Japan)

Author keywords

Bullous impetigo; Skin barrier; Tight junction

Indexed keywords

BACTERIAL TOXIN; DESMOGLEIN 1; EXFOLIATIN; IMMUNOGLOBULIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ADULT; AGED; ARTICLE; CELL JUNCTION; CLINICAL ARTICLE; DESMOSOME; DIFFUSION; EPIDERMIS; EPIDERMIS GRANULAR LAYER; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; IMPETIGO BULLOSA; KERATINOCYTE; MACROMOLECULE; MALE; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STRATUM CORNEUM; TIGHT JUNCTION;

BULLOUS IMPETIGO; SKIN BARRIER; TIGHT JUNCTION;

ADHERENS JUNCTIONS; ADULT; AGED; ANIMALS; DESMOGLEIN 1; DESMOSOMES; DIFFUSION; EPIDERMIS; FEMALE; HUMANS; IMPETIGO; KERATINOCYTES; MACROMOLECULAR SUBSTANCES; MALE; MICE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; PERMEABILITY; SINGLE-CHAIN ANTIBODIES; TIGHT JUNCTIONS;

EID: 84880325086     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.04.021     Document Type: Article

References (52)

1. Schempp C., Emde M., Wölfle U. Dermatology in the Darwin anniversary. Part 1: Evolution of the integument. J Dtsch Dermatol Ges 2009, 7:750-757.
2. Farquhar M.G., Palade G.E. Cell junctions in amphibian skin. J Cell Biol 1965, 26:263-291.
3. Landmann L., Stolinski C., Martin B. The permeability barrier in the epidermis of the grass snake during the resting stage of the sloughing cycle. Cell Tissue Res 1981, 215:369-382.
4. Furuse M., Hata M., Furuse K., Yoshida Y., Haratake A., Sugitani Y., et al. Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol 2002, 156:1099-1111.
5. Kubo A., Nagao K., Yokouchi M., Sasaki H., Amagai M. External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. J Exp Med 2009, 206:2937-2946.
6. Kirschner N., Houdek P., Fromm M., Moll I., Brandner J.M. Tight junctions form a barrier in human epidermis. Eur J Cell Biol 2010, 89:839-842.
7. Yuki T., Hachiya A., Kusaka A., Sriwiriyanont P., Visscher M.O., Morita K., et al. Characterization of tight junctions and their disruption by UVB in human epidermis and cultured keratinocytes. J Invest Dermatol 2011, 131:744-752.
8. De Benedetto A., Rafaels N.M., McGirt L.Y., Ivanov A.I., Georas S.N., Cheadle C., et al. Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol 2011, 127:773-786.
9. Mackenzie I.C. Ordered structure of the epidermis. J Invest Dermatol 1975, 65:45-51.
10. Mackenzie I.C., Linder J.E. An examination of cellular organization within the stratum corneum by a silver staining method. J Invest Dermatol 1973, 61:245-250.
11. Christophers E. Cellular architecture of the stratum corneum. J Invest Dermatol 1971, 56:165-169.
12. Mackenzie I.C. Relationship between mitosis and the ordered structure of the stratum corneum in mouse epidermis. Nature 1970, 226:653-655.
13. Mackenzie I.C., Zimmerman K., Peterson L. The pattern of cellular organization of human epidermis. J Invest Dermatol 1981, 76:459-461.
14. Kligman A.M. A brief history of how the dead stratum corneum became alive. Skin barrier 2006, 15-24. Taylor & Francis Group, London. P.M. Elias, K.R. Feingold (Eds.).
15. Ishida-Yamamoto A., Kishibe M., Murakami M., Honma M., Takahashi H., Iizuka H. Lamellar granule secretion starts before the establishment of tight junction barrier for paracellular tracers in mammalian epidermis. PLoS ONE 2012, 7:e31641.
16. Ouchi T., Kubo A., Yokouchi M., Adachi T., Kobayashi T., Kitashima D., et al. Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome. J Exp Med 2011, 208:2607-2613.
17. Hashimoto K. Intercellular spaces of the human epidermis as demonstrated with lanthanum. J Invest Dermatol 1971, 57:17-31.
18. Chen Y., Merzdorf C., Paul D.L., Goodenough D.A. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J Cell Biol 1997, 138:891-899.
19. Ishii K., Lin C., Siegel D.L., Stanley J.R. Isolation of pathogenic monoclonal anti-desmoglein 1 human antibodies by phage display of pemphigus foliaceus autoantibodies. J Invest Dermatol 2008, 128:939-948.
20. Hanakawa Y., Schechter N.M., Lin C., Garza L., Li H., Yamaguchi T., et al. Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. J Clin Invest 2002, 110:53-60.
21. Cavarelli J., Prévost G., Bourguet W., Moulinier L., Chevrier B., Delagoutte B., et al. The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7Å resolution. Structure 1997, 5:813-824.
22. Vath G.M., Earhart C.A., Rago J.V., Kim M.H., Bohach G.A., Schlievert P.M., et al. The structure of the superantigen exfoliative toxin A suggests a novel regulation as a serine protease. Biochemistry 1997, 36:1559-1566.
23. Meder D., Shevchenko A., Simons K., Füllekrug J. Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. J Cell Biol 2005, 168:303-313.
24. Itoh M., Yonemura S., Nagafuchi A., Tsukita S., Tsukita S. A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J Cell Biol 1991, 115:1449-1462.
25. Nagafuchi A., Tsukita S. The loss of the expression of alpha catenin, the 102kD cadherin associated protein, in central nervous tissues during development. Dev Growth Differ 1994, 36:59-71.
26. Saitou M., Ando-Akatsuka Y., Itoh M., Furuse M., Inazawa J., Fujimoto K., et al. Mammalian occludin in epithelial cells: its expression and subcellular distribution. Eur J Cell Biol 1997, 73:222-231.
27. Brandner J.M., Kief S., Grund C., Rendl M., Houdek P., Kuhn C., et al. Organization and formation of the tight junction system in human epidermis and cultured keratinocytes. Eur J Cell Biol 2002, 81:253-263.
28. Pummi K., Malminen M., Aho H., Karvonen S.L., Peltonen J., Peltonen S. Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes. J Invest Dermatol 2001, 117:1050-1058.
29. Schlüter H., Wepf R., Moll I., Franke W.W. Sealing the live part of the skin: the integrated meshwork of desmosomes, tight junctions and curvilinear ridge structures in the cells of the uppermost granular layer of the human epidermis. Eur J Cell Biol 2004, 83:655-665.
30. Takai Y., Ikeda W., Ogita H., Rikitake Y. The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin. Annu Rev Cell Dev Biol 2008, 24:309-342.
31. Doyonnas R., Kershaw D.B., Duhme C., Merkens H., Chelliah S., Graf T., et al. Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin. J Exp Med 2001, 194:13-27.
32. McNagny K.M., Pettersson I., Rossi F., Flamme I., Shevchenko A., Mann M., et al. Thrombomucin, a novel cell surface protein that defines thrombocytes and multipotent hematopoietic progenitors. J Cell Biol 1997, 138:1395-1407.
33. Sassetti C., Tangemann K., Singer M.S., Kershaw D.B., Rosen S.D. Identification of podocalyxin-like protein as a high endothelial venule ligand for l-selectin: parallels to CD34. J Exp Med 1998, 187:1965-1975.
34. Amagai M., Matsuyoshi N., Wang Z.H., Andl C., Stanley J.R. Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. Nat Med 2000, 6:1275-1277.
35. Amagai M., Yamaguchi T., Hanakawa Y., Nishifuji K., Sugai M., Stanley J.R. Staphylococcal exfoliative toxin B specifically cleaves desmoglein 1. J Invest Dermatol 2002, 118:845-850.
36. Nishifuji K., Shimizu A., Ishiko A., Iwasaki T., Amagai M. Removal of amino-terminal extracellular domains of desmoglein 1 by staphylococcal exfoliative toxin is sufficient to initiate epidermal blister formation. J Dermatol Sci 2010, 59:184-191.
37. Anderson J.M., Van Itallie C.M. Physiology and function of the tight junction. Cold Spring Harb Perspect Biol 2009, 1:a002584.
38. Cereijido M., Contreras R.G., Shoshani L., Flores-Benitez D., Larre I. Tight junction and polarity interaction in the transporting epithelial phenotype. Biochim Biophys Acta 2008, 1778:770-793.
39. Ovaere P., Lippens S., Vandenabeele P., Declercq W. The emerging roles of serine protease cascades in the epidermis. Trends Biochem Sci 2009, 34:453-463.
40. Candi E., Schmidt R., Melino G. The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 2005, 6:328-340.
41. Schlüter H., Moll I., Wolburg H., Franke W.W. The different structures containing tight junction proteins in epidermal and other stratified epithelial cells, including squamous cell metaplasia. Eur J Cell Biol 2007, 86:645-655.
42. Ando-Akatsuka Y., Yonemura S., Itoh M., Furuse M., Tsukita S. Differential behavior of E-cadherin and occludin in their colocalization with ZO-1 during the establishment of epithelial cell polarity. J Cell Physiol 1999, 179:115-125.
43. Hirschmann J.V. Impetigo: etiology and therapy. Current clinical topics in infectious diseases 2002, 42-51. Blackwell Publishing, Inc., Malden, MA. J.S. Remington, M.N. Swartz (Eds.).
44. Schröder J.M., Harder J. Antimicrobial skin peptides and proteins. Cell Mol Life Sci 2006, 63:469-486.
45. Schittek B., Hipfel R., Sauer B., Bauer J., Kalbacher H., Stevanovic S., et al. Dermcidin: a novel human antibiotic peptide secreted by sweat glands. Nat Immunol 2001, 2:1133-1137.
46. Braff M.H., Di Nardo A., Gallo R.L. Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies. J Invest Dermatol 2005, 124:394-400.
47. Aberg K.M., Man M.-Q., Gallo R.L., Ganz T., Crumrine D., Brown B.E., et al. Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol 2008, 128:917-925.
48. Oren A., Ganz T., Liu L., Meerloo T. In human epidermis, beta-defensin 2 is packaged in lamellar bodies. Exp Mol Pathol 2003, 74:180-182.
49. Kubo A., Nagao K., Amagai M. Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases. J Clin Invest 2012, 122:440-447.
50. Travers J.B., Norris D.A., Leung D.Y. The keratinocyte as a target for staphylococcal bacterial toxins. J Investig Dermatol Symp Proc 2001, 6:225-230.
51. Iwatsuki K., Yamasaki O., Morizane S., Oono T. Staphylococcal cutaneous infections: invasion, evasion and aggression. J Dermatol Sci 2006, 42:203-214.
52. Anderson J.M. Molecular structure of tight junctions and their role in epithelial transport. News Physiol Sci 2001, 16:126-130.