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Volumn 87, Issue 14, 2013, Pages 8053-8063

The B-cell-specific transcription factor and master regulator Pax5 promotes epstein-barr virus latency by negatively regulating the viral immediate early protein BZLF1

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; IMMEDIATE EARLY PROTEIN BZLF1; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR PAX5;

EID: 84880315168     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00546-13     Document Type: Article
Times cited : (30)

References (74)
  • 1
    • 34250010253 scopus 로고    scopus 로고
    • Epstein-Barr virus and its replication
    • Lippincott/The Williams & Wilkins Co, Philadelphia, PA
    • Kieff E, Rickinson AB. 2007. Epstein-Barr virus and its replication, p 2603-2654. In Knipe DM, Howley PM (ed), Fields virology, 5th ed. Lippincott/The Williams & Wilkins Co, Philadelphia, PA.
    • (2007) In Knipe DM, Howley PM (ed), Fields virology, 5th ed. , pp. 2603-2654
    • Kieff, E.1    Rickinson, A.B.2
  • 3
    • 29144534561 scopus 로고    scopus 로고
    • Peripheral B cells latently infected with Epstein-Barr virus display molecular hallmarks of classical antigen-selected memory B cells
    • Souza TA, Stollar BD, Sullivan JL, Luzuriaga K, Thorley-Lawson DA. 2005. Peripheral B cells latently infected with Epstein-Barr virus display molecular hallmarks of classical antigen-selected memory B cells. Proc. Natl. Acad. Sci. U. S. A. 102:18093-18098.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 18093-18098
    • Souza, T.A.1    Stollar, B.D.2    Sullivan, J.L.3    Luzuriaga, K.4    Thorley-Lawson, D.A.5
  • 4
    • 11144245265 scopus 로고    scopus 로고
    • Terminal differentiation into plasma cells initiates the replicative cycle of Epstein-Barr virus in vivo
    • Laichalk LL, Thorley-Lawson DA. 2005. Terminal differentiation into plasma cells initiates the replicative cycle of Epstein-Barr virus in vivo. J. Virol. 79:1296-1307.
    • (2005) J. Virol. , vol.79 , pp. 1296-1307
    • Laichalk, L.L.1    Thorley-Lawson, D.A.2
  • 5
    • 37849038673 scopus 로고    scopus 로고
    • ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus
    • doi:10.1371/journal.ppat.0030194
    • Yu X, Wang Z, Mertz JE. 2007. ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus. PLoS Pathog. 3:e194. doi:10.1371/journal.ppat.0030194.
    • (2007) PLoS Pathog. , vol.3
    • Yu, X.1    Wang, Z.2    Mertz, J.E.3
  • 6
    • 34447277651 scopus 로고    scopus 로고
    • X-boxbinding protein 1 activates lytic Epstein-Barr virus gene expression in combination with protein kinase D
    • Bhende PM, Dickerson SJ, Sun X, Feng WH, Kenney SC. 2007. X-boxbinding protein 1 activates lytic Epstein-Barr virus gene expression in combination with protein kinase D. J. Virol. 81:7363-7370.
    • (2007) J. Virol. , vol.81 , pp. 7363-7370
    • Bhende, P.M.1    Dickerson, S.J.2    Sun, X.3    Feng, W.H.4    Kenney, S.C.5
  • 8
    • 0034660443 scopus 로고    scopus 로고
    • The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators
    • Feederle R, Kost M, Baumann M, Janz A, Drouet E, Hammerschmidt W, Delecluse HJ. 2000. The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators. EMBO J. 19:3080-3089.
    • (2000) EMBO J. , vol.19 , pp. 3080-3089
    • Feederle, R.1    Kost, M.2    Baumann, M.3    Janz, A.4    Drouet, E.5    Hammerschmidt, W.6    Delecluse, H.J.7
  • 9
    • 0032506210 scopus 로고    scopus 로고
    • Rescue of the Epstein-Barr virus BZLF1 mutant, Z(S186A), early gene activation defect by the BRLF1 gene product
    • Adamson AL, Kenney SC. 1998. Rescue of the Epstein-Barr virus BZLF1 mutant, Z(S186A), early gene activation defect by the BRLF1 gene product. Virology 251:187-197.
    • (1998) Virology , vol.251 , pp. 187-197
    • Adamson, A.L.1    Kenney, S.C.2
  • 10
    • 77955794374 scopus 로고    scopus 로고
    • MCAF1 and synergistic activation of the transcription of Epstein-Barr virus lytic genes by Rta and Zta
    • Chang LK, Chuang JY, Nakao M, Liu ST. 2010. MCAF1 and synergistic activation of the transcription of Epstein-Barr virus lytic genes by Rta and Zta. Nucleic Acids Res. 38:4687-4700.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 4687-4700
    • Chang, L.K.1    Chuang, J.Y.2    Nakao, M.3    Liu, S.T.4
  • 11
    • 0025177308 scopus 로고
    • An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators
    • Cox MA, Leahy J, Hardwick JM. 1990. An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators. J. Virol. 64:313-321.
    • (1990) J. Virol. , vol.64 , pp. 313-321
    • Cox, M.A.1    Leahy, J.2    Hardwick, J.M.3
  • 12
    • 0034974152 scopus 로고    scopus 로고
    • Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation
    • Darr CD, Mauser A, Kenney S. 2001. Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation. J. Virol. 75: 6135-6142.
    • (2001) J. Virol. , vol.75 , pp. 6135-6142
    • Darr, C.D.1    Mauser, A.2    Kenney, S.3
  • 13
    • 0024469056 scopus 로고
    • Epstein-Barr virus BZLF1 transactivator specifically binds to a consensus AP-1 site and is related to c-fos
    • Farrell PJ, Rowe DT, Rooney CM, Kouzarides T. 1989. Epstein-Barr virus BZLF1 transactivator specifically binds to a consensus AP-1 site and is related to c-fos. EMBO J. 8:127-132.
    • (1989) EMBO J. , vol.8 , pp. 127-132
    • Farrell, P.J.1    Rowe, D.T.2    Rooney, C.M.3    Kouzarides, T.4
  • 14
    • 0025214570 scopus 로고
    • Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1
    • Flemington E, Speck SH. 1990. Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1. J. Virol. 64:1227-1232.
    • (1990) J. Virol. , vol.64 , pp. 1227-1232
    • Flemington, E.1    Speck, S.H.2
  • 15
    • 0025666546 scopus 로고
    • The enhancer factor R of Epstein-Barr virus (EBV) is a sequence-specific DNA binding protein
    • Gruffat H, Manet E, Rigolet A, Sergeant A. 1990. The enhancer factor R of Epstein-Barr virus (EBV) is a sequence-specific DNA binding protein. Nucleic Acids Res. 18:6835-6843.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 6835-6843
    • Gruffat, H.1    Manet, E.2    Rigolet, A.3    Sergeant, A.4
  • 16
    • 0023889721 scopus 로고
    • A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen
    • Hardwick JM, Lieberman PM, Hayward SD. 1988. A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen. J. Virol. 62:2274-2284.
    • (1988) J. Virol. , vol.62 , pp. 2274-2284
    • Hardwick, J.M.1    Lieberman, P.M.2    Hayward, S.D.3
  • 17
    • 0024550905 scopus 로고
    • The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters
    • Kenney S, Kamine J, Holley-Guthrie E, Lin JC, Mar EC, Pagano J. 1989. The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters. J. Virol. 63: 1729-1736.
    • (1989) J. Virol. , vol.63 , pp. 1729-1736
    • Kenney, S.1    Kamine, J.2    Holley-Guthrie, E.3    Lin, J.C.4    Mar, E.C.5    Pagano, J.6
  • 18
    • 0025255970 scopus 로고
    • The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions
    • Lieberman PM, Hardwick JM, Sample J, Hayward GS, Hayward SD. 1990. The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions. J. Virol. 64:1143-1155.
    • (1990) J. Virol. , vol.64 , pp. 1143-1155
    • Lieberman, P.M.1    Hardwick, J.M.2    Sample, J.3    Hayward, G.S.4    Hayward, S.D.5
  • 20
    • 0024379416 scopus 로고
    • The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle
    • Rooney CM, Rowe DT, Ragot T, Farrell PJ. 1989. The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle. J. Virol. 63:3109-3116.
    • (1989) J. Virol. , vol.63 , pp. 3109-3116
    • Rooney, C.M.1    Rowe, D.T.2    Ragot, T.3    Farrell, P.J.4
  • 21
    • 0038678667 scopus 로고    scopus 로고
    • Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta
    • Liu P, Speck SH. 2003. Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta. Virology 310: 199-206.
    • (2003) Virology , vol.310 , pp. 199-206
    • Liu, P.1    Speck, S.H.2
  • 22
    • 0029830047 scopus 로고    scopus 로고
    • Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism
    • Zalani S, Holley-Guthrie E, Kenney S. 1996. Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism. Proc. Natl. Acad. Sci. U. S. A. 93:9194-9199.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 9194-9199
    • Zalani, S.1    Holley-Guthrie, E.2    Kenney, S.3
  • 23
    • 0023503201 scopus 로고
    • Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency
    • Countryman J, Jenson H, Seibl R, Wolf H, Miller G. 1987. Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency. J. Virol. 61:3672-3679.
    • (1987) J. Virol. , vol.61 , pp. 3672-3679
    • Countryman, J.1    Jenson, H.2    Seibl, R.3    Wolf, H.4    Miller, G.5
  • 24
    • 0022646563 scopus 로고
    • trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment
    • Takada K, Shimizu N, Sakuma S, Ono Y. 1986. trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment. J. Virol. 57:1016-1022.
    • (1986) J. Virol. , vol.57 , pp. 1016-1022
    • Takada, K.1    Shimizu, N.2    Sakuma, S.3    Ono, Y.4
  • 25
    • 6944244957 scopus 로고    scopus 로고
    • The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome
    • Bhende PM, Seaman WT, Delecluse HJ, Kenney SC. 2004. The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome. Nat. Genet. 36:1099-1104.
    • (2004) Nat. Genet. , vol.36 , pp. 1099-1104
    • Bhende, P.M.1    Seaman, W.T.2    Delecluse, H.J.3    Kenney, S.C.4
  • 26
    • 19944397140 scopus 로고    scopus 로고
    • BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186
    • Bhende PM, Seaman WT, Delecluse HJ, Kenney SC. 2005. BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. J. Virol. 79:7338-7348.
    • (2005) J. Virol. , vol.79 , pp. 7338-7348
    • Bhende, P.M.1    Seaman, W.T.2    Delecluse, H.J.3    Kenney, S.C.4
  • 27
    • 63449134294 scopus 로고    scopus 로고
    • Methylation-dependent binding of the Epstein-Barr virus BZLF1 protein to viral promoters
    • doi:10.1371/journal.ppat.1000356
    • Dickerson SJ, Xing Y, Robinson AR, Seaman WT, Gruffat H, Kenney SC. 2009. Methylation-dependent binding of the Epstein-Barr virus BZLF1 protein to viral promoters. PLoS Pathog. 5:e1000356. doi:10.1371/journal.ppat.1000356.
    • (2009) PLoS Pathog. , vol.5
    • Dickerson, S.J.1    Xing, Y.2    Robinson, A.R.3    Seaman, W.T.4    Gruffat, H.5    Kenney, S.C.6
  • 28
    • 84871986829 scopus 로고    scopus 로고
    • Viral genome methylation differentially affects the ability of BZLF1 versus BRLF1 to activate Epstein-Barr virus lytic gene expression and viral replication
    • Wille CK, Nawandar DM, Panfil AR, Ko MM, Hagemeier SR, Kenney SC. 2013. Viral genome methylation differentially affects the ability of BZLF1 versus BRLF1 to activate Epstein-Barr virus lytic gene expression and viral replication. J. Virol. 87:935-950.
    • (2013) J. Virol. , vol.87 , pp. 935-950
    • Wille, C.K.1    Nawandar, D.M.2    Panfil, A.R.3    Ko, M.M.4    Hagemeier, S.R.5    Kenney, S.C.6
  • 30
    • 76249132533 scopus 로고    scopus 로고
    • AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome
    • Kalla M, Schmeinck A, Bergbauer M, Pich D, Hammerschmidt W. 2010. AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc. Natl. Acad. Sci. U. S. A. 107:850-855.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 850-855
    • Kalla, M.1    Schmeinck, A.2    Bergbauer, M.3    Pich, D.4    Hammerschmidt, W.5
  • 31
    • 80053966424 scopus 로고    scopus 로고
    • Epigenetic control of viral life-cycle by a DNA-methylationdependent transcription factor
    • doi:10.1371/journal.pone.0025922
    • Flower K, Thomas D, Heather J, Ramasubramanyan S, Jones S, Sinclair AJ. 2011. Epigenetic control of viral life-cycle by a DNA-methylationdependent transcription factor. PLoS One 6:e25922. doi:10.1371/journal.pone.0025922.
    • (2011) PLoS One , vol.6
    • Flower, K.1    Thomas, D.2    Heather, J.3    Ramasubramanyan, S.4    Jones, S.5    Sinclair, A.J.6
  • 33
    • 0025975985 scopus 로고
    • DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
    • Boyes J, Bird A. 1991. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 64:1123-1134.
    • (1991) Cell , vol.64 , pp. 1123-1134
    • Boyes, J.1    Bird, A.2
  • 34
    • 0026583975 scopus 로고
    • Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein
    • Boyes J, Bird A. 1992. Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein. EMBO J. 11:327-333.
    • (1992) EMBO J. , vol.11 , pp. 327-333
    • Boyes, J.1    Bird, A.2
  • 35
    • 0032168678 scopus 로고    scopus 로고
    • CpG methylation, chromatin structure, and gene silencing: a three-way connection
    • Razin A. 1998. CpG methylation, chromatin structure, and gene silencing: a three-way connection. EMBO J. 17:4905-4908.
    • (1998) EMBO J. , vol.17 , pp. 4905-4908
    • Razin, A.1
  • 36
    • 0024081657 scopus 로고
    • Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter
    • Watt F, Molloy PL. 1988. Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev. 2:1136-1143.
    • (1988) Genes Dev. , vol.2 , pp. 1136-1143
    • Watt, F.1    Molloy, P.L.2
  • 37
    • 80053456532 scopus 로고    scopus 로고
    • Pax5: a master regulator of B cell development and leukemogenesis
    • Medvedovic J, Ebert A, Tagoh H, Busslinger M. 2011. Pax5: a master regulator of B cell development and leukemogenesis. Adv. Immunol. 111: 179-206.
    • (2011) Adv. Immunol. , vol.111 , pp. 179-206
    • Medvedovic, J.1    Ebert, A.2    Tagoh, H.3    Busslinger, M.4
  • 39
    • 33644664045 scopus 로고    scopus 로고
    • Transcription factors drive B cell development
    • Hagman J, Lukin K. 2006. Transcription factors drive B cell development. Curr. Opin. Immunol. 18:127-134.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 127-134
    • Hagman, J.1    Lukin, K.2
  • 40
    • 23744485559 scopus 로고    scopus 로고
    • Early B-cell factor "pioneers" the way for B-cell development
    • Hagman J, Lukin K. 2005. Early B-cell factor "pioneers" the way for B-cell development. Trends Immunol. 26:455-461.
    • (2005) Trends Immunol. , vol.26 , pp. 455-461
    • Hagman, J.1    Lukin, K.2
  • 42
    • 2542455620 scopus 로고    scopus 로고
    • Stepwise reprogramming of B cells into macrophages
    • Xie H, Ye M, Feng R, Graf T. 2004. Stepwise reprogramming of B cells into macrophages. Cell 117:663-676.
    • (2004) Cell , vol.117 , pp. 663-676
    • Xie, H.1    Ye, M.2    Feng, R.3    Graf, T.4
  • 43
    • 79954624563 scopus 로고    scopus 로고
    • Histone acetyltransferase p300 acetylates Pax5 and strongly enhances Pax5-mediated transcriptional activity
    • He T, Hong SY, Huang L, Xue W, Yu Z, Kwon H, Kirk M, Ding SJ, Su K, Zhang Z. 2011. Histone acetyltransferase p300 acetylates Pax5 and strongly enhances Pax5-mediated transcriptional activity. J. Biol. Chem. 286:14137-14145.
    • (2011) J. Biol. Chem. , vol.286 , pp. 14137-14145
    • He, T.1    Hong, S.Y.2    Huang, L.3    Xue, W.4    Yu, Z.5    Kwon, H.6    Kirk, M.7    Ding, S.J.8    Su, K.9    Zhang, Z.10
  • 44
    • 34547126466 scopus 로고    scopus 로고
    • Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function
    • Schebesta A, McManus S, Salvagiotto G, Delogu A, Busslinger GA, Busslinger M. 2007. Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function. Immunity 27:49-63.
    • (2007) Immunity , vol.27 , pp. 49-63
    • Schebesta, A.1    McManus, S.2    Salvagiotto, G.3    Delogu, A.4    Busslinger, G.A.5    Busslinger, M.6
  • 45
    • 0036798665 scopus 로고    scopus 로고
    • Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene
    • Schebesta M, Pfeffer PL, Busslinger M. 2002. Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene. Immunity 17: 473-485.
    • (2002) Immunity , vol.17 , pp. 473-485
    • Schebesta, M.1    Pfeffer, P.L.2    Busslinger, M.3
  • 46
    • 33751201517 scopus 로고    scopus 로고
    • Pax5 maintains cellular identity by repressing gene expression throughout B cell differentiation
    • Carotta S, Holmes ML, Pridans C, Nutt SL. 2006. Pax5 maintains cellular identity by repressing gene expression throughout B cell differentiation. Cell Cycle 5:2452-2456.
    • (2006) Cell Cycle , vol.5 , pp. 2452-2456
    • Carotta, S.1    Holmes, M.L.2    Pridans, C.3    Nutt, S.L.4
  • 50
    • 0033760926 scopus 로고    scopus 로고
    • Methylation of transcription factor binding sites in the Epstein-Barr virus latent cycle promoter Wp coincides with promoter downregulation during virus-induced B-cell transformation
    • Tierney RJ, Kirby HE, Nagra JK, Desmond J, Bell AI, Rickinson AB. 2000. Methylation of transcription factor binding sites in the Epstein-Barr virus latent cycle promoter Wp coincides with promoter downregulation during virus-induced B-cell transformation. J. Virol. 74:10468-10479.
    • (2000) J. Virol. , vol.74 , pp. 10468-10479
    • Tierney, R.J.1    Kirby, H.E.2    Nagra, J.K.3    Desmond, J.4    Bell, A.I.5    Rickinson, A.B.6
  • 52
    • 32544452682 scopus 로고    scopus 로고
    • Modeling early Epstein-Barr virus infection in Drosophila melanogaster: the BZLF1 protein
    • Adamson AL, Wright N, LaJeunesse DR. 2005. Modeling early Epstein-Barr virus infection in Drosophila melanogaster: the BZLF1 protein. Genetics 171:1125-1135.
    • (2005) Genetics , vol.171 , pp. 1125-1135
    • Adamson, A.L.1    Wright, N.2    LaJeunesse, D.R.3
  • 53
    • 19944391936 scopus 로고    scopus 로고
    • Epstein-Barr virus BZLF1 protein binds to mitotic chromosomes
    • Adamson AL. 2005. Epstein-Barr virus BZLF1 protein binds to mitotic chromosomes. J. Virol. 79:7899-7904.
    • (2005) J. Virol. , vol.79 , pp. 7899-7904
    • Adamson, A.L.1
  • 54
    • 0036272784 scopus 로고    scopus 로고
    • Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells
    • Lin KI, Angelin-Duclos C, Kuo TC, Calame K. 2002. Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. Mol. Cell. Biol. 22:4771-4780.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4771-4780
    • Lin, K.I.1    Angelin-Duclos, C.2    Kuo, T.C.3    Calame, K.4
  • 56
    • 70249148999 scopus 로고    scopus 로고
    • Initiation of antigen receptor-dependent differentiation into plasma cells by calmodulin inhibition of E2A
    • Hauser J, Verma-Gaur J, Wallenius A, Grundstrom T. 2009. Initiation of antigen receptor-dependent differentiation into plasma cells by calmodulin inhibition of E2A. J. Immunol. 183:1179-1187.
    • (2009) J. Immunol. , vol.183 , pp. 1179-1187
    • Hauser, J.1    Verma-Gaur, J.2    Wallenius, A.3    Grundstrom, T.4
  • 57
    • 0021351866 scopus 로고
    • Cross-linking of cell surface immunoglobulins induces Epstein-Barr virus in Burkitt lymphoma lines
    • Takada K. 1984. Cross-linking of cell surface immunoglobulins induces Epstein-Barr virus in Burkitt lymphoma lines. Int. J. Cancer 33:27-32.
    • (1984) Int. J. Cancer , vol.33 , pp. 27-32
    • Takada, K.1
  • 58
    • 0027243214 scopus 로고
    • Analysis of the BZLF1 promoter of Epstein-Barr virus: identification of an anti-immunoglobulin response sequence
    • Shimizu N, Takada K. 1993. Analysis of the BZLF1 promoter of Epstein-Barr virus: identification of an anti-immunoglobulin response sequence. J. Virol. 67:3240-3245.
    • (1993) J. Virol. , vol.67 , pp. 3240-3245
    • Shimizu, N.1    Takada, K.2
  • 60
    • 0024332127 scopus 로고
    • Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas
    • Glaser R, Zhang HY, Yao KT, Zhu HC, Wang FX, Li GY, Wen DS, Li YP. 1989. Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas. Proc. Natl. Acad. Sci. U. S. A. 86:9524-9528.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 9524-9528
    • Glaser, R.1    Zhang, H.Y.2    Yao, K.T.3    Zhu, H.C.4    Wang, F.X.5    Li, G.Y.6    Wen, D.S.7    Li, Y.P.8
  • 61
    • 0016835245 scopus 로고
    • Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma
    • Menezes J, Leibold W, Klein G, Clements G. 1975. Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma. Biomedicine 22:276-284.
    • (1975) Biomedicine , vol.22 , pp. 276-284
    • Menezes, J.1    Leibold, W.2    Klein, G.3    Clements, G.4
  • 62
    • 0017710978 scopus 로고
    • Characteristics of a human cell line transformed by DNA from human adenovirus type 5
    • Graham FL, Smiley J, Russell WC, Nairn R. 1977. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 36:59-74.
    • (1977) J. Gen. Virol. , vol.36 , pp. 59-74
    • Graham, F.L.1    Smiley, J.2    Russell, W.C.3    Nairn, R.4
  • 63
    • 0029861946 scopus 로고    scopus 로고
    • A replication function associated with the activation domain of the Epstein-Barr virus Zta transactivator
    • Sarisky RT, Gao Z, Lieberman PM, Fixman ED, Hayward GS, Hayward SD. 1996. A replication function associated with the activation domain of the Epstein-Barr virus Zta transactivator. J. Virol. 70:8340-8347.
    • (1996) J. Virol. , vol.70 , pp. 8340-8347
    • Sarisky, R.T.1    Gao, Z.2    Lieberman, P.M.3    Fixman, E.D.4    Hayward, G.S.5    Hayward, S.D.6
  • 64
    • 0029833870 scopus 로고    scopus 로고
    • Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter
    • Fitzsimmons D, Hodsdon W, Wheat W, Maira SM, Wasylyk B, Hagman J. 1996. Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter. Genes Dev. 10:2198-2211.
    • (1996) Genes Dev. , vol.10 , pp. 2198-2211
    • Fitzsimmons, D.1    Hodsdon, W.2    Wheat, W.3    Maira, S.M.4    Wasylyk, B.5    Hagman, J.6
  • 65
    • 84860904972 scopus 로고    scopus 로고
    • The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1
    • doi:10.1371/journal.ppat.1002516
    • Robinson AR, Kwek SS, Kenney SC. 2012. The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1. PLoS Pathog. 8:e1002516. doi:10.1371/journal.ppat.1002516.
    • (2012) PLoS Pathog. , vol.8
    • Robinson, A.R.1    Kwek, S.S.2    Kenney, S.C.3
  • 66
    • 0035862177 scopus 로고    scopus 로고
    • Optimal Oct-2 affinity for an extended DNA site and the effect of GST fusion on site preference
    • Rhee JM, Trieu M, Turner EE. 2001. Optimal Oct-2 affinity for an extended DNA site and the effect of GST fusion on site preference. Arch. Biochem. Biophys. 385:397-405.
    • (2001) Arch. Biochem. Biophys. , vol.385 , pp. 397-405
    • Rhee, J.M.1    Trieu, M.2    Turner, E.E.3
  • 67
    • 0033381579 scopus 로고    scopus 로고
    • A human early B-cell factorlike protein participates in the regulation of the human CD19 promoter
    • Gisler R, Akerblad P, Sigvardsson M. 1999. A human early B-cell factorlike protein participates in the regulation of the human CD19 promoter. Mol. Immunol. 36:1067-1077.
    • (1999) Mol. Immunol. , vol.36 , pp. 1067-1077
    • Gisler, R.1    Akerblad, P.2    Sigvardsson, M.3
  • 68
    • 38449102144 scopus 로고    scopus 로고
    • Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
    • Klug M, Rehli M. 2006. Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 1:127-130.
    • (2006) Epigenetics , vol.1 , pp. 127-130
    • Klug, M.1    Rehli, M.2
  • 70
    • 0034979367 scopus 로고    scopus 로고
    • Epstein-Barr virus immediate-early protein BRLF1 interacts with CBP, promoting enhanced BRLF1 transactivation
    • Swenson JJ, Holley-Guthrie E, Kenney SC. 2001. Epstein-Barr virus immediate-early protein BRLF1 interacts with CBP, promoting enhanced BRLF1 transactivation. J. Virol. 75:6228-6234.
    • (2001) J. Virol. , vol.75 , pp. 6228-6234
    • Swenson, J.J.1    Holley-Guthrie, E.2    Kenney, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.