Comparison of analgesic effect of direct breastfeeding, oral 25% dextrose solution and placebo during 1st DPT vaccination in healthy term infants: A randomized, placebo controlled trial

Indian Pediatrics

Volumn 50, Issue 7, 2013, Pages 649-653

  Goswami, Gaurav ^a   Upadhyay, Amit ^a   Gupta, Navratan Kumar ^a   Chaudhry, Rajesh ^a   Chawla, Deepak ^b   Sreenivas, V ^c  

^a LLRM MEDICAL COLLEGE   (India)

^b GOVERNMENT MEDICAL COLLEGE AND HOSPITAL   (India)

^c ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

25 dextrose; Breastfeeding; DPT vaccination; Duration of cry; Infant; Management; Pain

Indexed keywords

DIPHTHERIA PERTUSSIS TETANUS VACCINE; DISTILLED WATER; GLUCOSE; PLACEBO; UNCLASSIFIED DRUG; WATER; ANALGESIC AGENT;

ANALGESIC ACTIVITY; ARTICLE; BREAST FEEDING; CONTROLLED STUDY; CRYING; HUMAN; INFANT; MODIFIED FACIAL CODING SCORE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OUTCOME VARIABLE; PEDIATRIC WARD; RANDOMIZED CONTROLLED TRIAL; VACCINATION; ANALGESIA; FACIAL EXPRESSION; PAIN MEASUREMENT; PROCEDURES;

ANALGESICS; BREAST FEEDING; DIPHTHERIA-TETANUS-PERTUSSIS VACCINE; FACIAL EXPRESSION; GLUCOSE; HUMANS; INFANT; PAIN MANAGEMENT; PAIN MEASUREMENT; PLACEBOS;

EID: 84880305044     PISSN: 00196061     EISSN: 09747559     Source Type: Journal    
DOI: 10.1007/s13312-013-0196-8     Document Type: Article

References (23)

1. Grunau RVE, Graig KD. Pain expression in neonates; facial action and cry. Pain. 1987;28:395-410.
2. Barr RG. Reflections on measuring pain in infants: Dissociation in responsive systems and "honest signaling". Arch Dis Child Fetal Neonatal Ed. 1998;79:F152-F156.
3. Anand KJ. International Evidence-Based Group for Neonatal Pain. Consensus statement for the prevention and management of pain in the newborn. Arch Pediatr Adolesc Med. 2001;155:173-180.
4. Stevens B, Yamada J, Ohlsson A. Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev. 2010;1:CD001069.
5. Carbajal R, Chauvet X, Couderc S, Olivier-Martin M. Randomised trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates. BMJ. 1999;319:1393-1397.
6. Bucher HU, Baumgartner R, Bucher N, Seiler M, Fauchère JC. Artificial sweetener reduces nociceptive reaction in term newborn infants. Early Hum Dev. 2000;59:51-60.
7. Harrison D, Stevens B, Bueno M, Yamada J, Adams-Webber T, Beyene J, et al. Efficacy of sweet solutions for analgesia in infants between 1 and 12 months of age: a systematic review. Arch Dis Child Fetal Neonatal Ed. 2010;95:406-413.
8. Stevens B, Taddio A, Ohlsson A, Einarson T. The efficacy of sucrose for relieving procedural pain neonates-a systemstic review and metaanalysis. Acta Pediatr. 1997;86:837-842.
9. Upadhyay A, Aggarwal R, Narayan S, Joshi M, Paul VK, Deorari AK. Analgesic effect of expressed breast milk in procedural pain in term neonates: a randomized, placebocontrolled, double-blind trial. Acta Paediatr. 2004;93:518-522.
10. Uyan ZS, Ozek E, Bilgen H, Cebeci D, Akman I. Effect of foremilk and hindmilk on simple procedural pain in newborns. Pediatr Int. 2005;47:252-257.
11. Osinaike BB, Oyedeji AO, Adeoye OT, Dairo MD, Aderinto DA. Effect of breastfeeding during venepuncture in neonates. Ann Trop Paediatr. 2007;27:201-205.
12. Singh VB, Mishra SK, Singh T, Upadhyay A. Antinociceptive effect of exclusive breastfeeding in healthy term infants during vaccination. Early Human Development. 2008;84:50-51.
13. Uga E, Candriella M, Perino A, Alloni V, Angilella G, Trada M, et al. Heel lance in newborn during breastfeeding: an evaluation of analgesic effect of this procedure. Ital J Pediatr. 2008;34:3.
14. Skogsdal Y, Erricson M, Schollin. Analgesia in newborns given oral glucose. Acta Pediatr. 1997;86:217-220.
15. Ramenghi LA, Wood CM, Griffith GC, Levene MI. Reduction of pain response in premature infants using intraoral sucrose. Arch Dis Child Fetal Neonatal Ed. 1996;74:F126-F128.
16. Gonsolves S, Mercer J. Physiological correlates of painful stimulation in preterm infants. Clin J Pain. 1993;9:88-93.
17. Gray L, Watt L, Blass EM. Skin-to-skin contact is analgesic in healthy newborns. Pediatrics. 2000;105:252-257.
18. Okan F, Ozdil A, Bulbul A, Yapici Z, Nuhoglu A. Analgesic effects of skin-to-skin contact and breastfeeding in procedural pain in healthy term neonates. Ann Trop Paediatr. 2010;30:119-128.
19. Efe E, Ozer ZC. The use of breast-feeding for pain relief during neonatal immunization injections. Appl Nurs Res. 2007;20:10-16.
20. Phillips RM, Chantry CJ, Gallagher MP. Analgesic effects of breast-feeding or pacifier use with maternal holding in term infants. Ambul Pediatr. 2005;5:359-364.
21. Gray L, Miller LW, Philipp BL, Blass EM. Breastfeeding is analgesic in healthy newborns. Pediatrics. 2002;109:590-593.
22. Codipietro L, Ceccarelli M, Ponzone A. Breastfeeding or oral sucrose solution in term neonates receiving heel lance: A randomized, controlled trial. Pediatrics. 2008;122:716-721.
23. Shah PS, Aliwalas L, Shah V. Breastfeeding or breast milk to alleviate procedural pain in neonates: a systematic review. Breastfeed Med. 2007;2:74-82.