메뉴 건너뛰기




Volumn 35, Issue 7, 2013, Pages 1038-1043

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and susceptibility to diabetic nephropathy in Chinese type 2 diabetic patients: A meta-analysis

Author keywords

C677T polymorphism; Chinese; Diabetes mellitus; Diabetic nephropathy; Meta analysis; Methylenetetrahydrofolate reductase

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

EID: 84880295205     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2013.810542     Document Type: Review
Times cited : (19)

References (45)
  • 2
    • 0037061867 scopus 로고    scopus 로고
    • Clinical practice. Nephropathy in patients with type 2 diabetes
    • Remuzzi G, Schieppati A, Ruggenenti P. Clinical practice. Nephropathy in patients with type 2 diabetes. N Engl J Med. 2002;346:1145-1151.
    • (2002) N Engl J Med. , vol.346 , pp. 1145-1151
    • Remuzzi, G.1    Schieppati, A.2    Ruggenenti, P.3
  • 3
    • 0032990386 scopus 로고    scopus 로고
    • Genetic determinants of diabetic nephropathy
    • Chowdhury TA, Dyer PH, Kumar S, et al. Genetic determinants of diabetic nephropathy. Clin Sci (Lond). 1999;96(3):221-230.
    • (1999) Clin Sci (Lond). , vol.96 , Issue.3 , pp. 221-230
    • Chowdhury, T.A.1    Dyer, P.H.2    Kumar, S.3
  • 4
    • 33645804043 scopus 로고    scopus 로고
    • Influence of apolipoprotein e genotype on progression of diabetic nephropathy
    • Joss N, Jardine A, Gaffney D, et al. Influence of apolipoprotein E genotype on progression of diabetic nephropathy. Nephron Exp Nephrol. 2005;101(4):e127-e133.
    • (2005) Nephron Exp Nephrol. , vol.101 , Issue.4
    • Joss, N.1    Jardine, A.2    Gaffney, D.3
  • 5
    • 0029994018 scopus 로고    scopus 로고
    • Familial factors determine the development of diabetic nephropathy in patients with IDDM
    • Quinn M, Angelico MC, Warram JH, et al. Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia. 1996;39(8):940-945.
    • (1996) Diabetologia. , vol.39 , Issue.8 , pp. 940-945
    • Quinn, M.1    Angelico, M.C.2    Warram, J.H.3
  • 6
    • 33645067138 scopus 로고    scopus 로고
    • Familial factors in diabetic nephropathy: An off-spring study
    • Agius E, Attard G, Shakespeare L, et al. Familial factors in diabetic nephropathy: an off-spring study. Diabet Med. 2006;23:331-334.
    • (2006) Diabet Med. , vol.23 , pp. 331-334
    • Agius, E.1    Attard, G.2    Shakespeare, L.3
  • 7
    • 0012355336 scopus 로고    scopus 로고
    • Diabetes mellitus and hyperhomocysteinemia
    • Guldener CV, Stehouwer CDA. Diabetes mellitus and hyperhomocysteinemia. Semin Vasc Med. 2002;2:351-359.
    • (2002) Semin Vasc Med. , vol.2 , pp. 351-359
    • Guldener, C.V.1    Stehouwer, C.D.A.2
  • 8
    • 0043166547 scopus 로고    scopus 로고
    • Effects of the C677T and A1298C polymorphisms of the MTHFR gene on the genetic predisposition for diabetic nephropathy
    • Moczulski D, Fojcik H, Zukowska-Szczechowska E, et al. Effects of the C677T and A1298C polymorphisms of the MTHFR gene on the genetic predisposition for diabetic nephropathy. Nephrol Dial Transplant. 2003;18:1535-1540.
    • (2003) Nephrol Dial Transplant. , vol.18 , pp. 1535-1540
    • Moczulski, D.1    Fojcik, H.2    Zukowska-Szczechowska, E.3
  • 9
    • 0347004549 scopus 로고    scopus 로고
    • Elevated plasma homocysteine level is an independent predictor of coronary heart disease events in patients with type 2 diabetes mellitus
    • Minna S, Jukka M, Markku L, et al. Elevated plasma homocysteine level is an independent predictor of coronary heart disease events in patients with type 2 diabetes mellitus. Ann Inter Med. 2004;140: 94-100.
    • (2004) Ann Inter Med. , vol.140 , pp. 94-100
    • Minna, S.1    Jukka, M.2    Markku, L.3
  • 10
    • 10944234529 scopus 로고    scopus 로고
    • Effect of folic acid on methionine and homocysteine metabolism in end-stage renal disease
    • Stam F, Guldener CV, Wee PMT, et al. Effect of folic acid on methionine and homocysteine metabolism in end-stage renal disease. Kidney Int. 2000;567:259-264.
    • (2000) Kidney Int. , vol.567 , pp. 259-264
    • Stam, F.1    Guldener, C.V.2    Wee, P.M.T.3
  • 11
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995;10:111-113.
    • (1995) Nat Genet. , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 12
    • 36749104379 scopus 로고    scopus 로고
    • The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy
    • Eroglu Z, Erdogan M, Tetik A, et al. The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy. Diab Metab Res Rev. 2007;23:621-624.
    • (2007) Diab Metab Res Rev. , vol.23 , pp. 621-624
    • Eroglu, Z.1    Erdogan, M.2    Tetik, A.3
  • 13
    • 0033802994 scopus 로고    scopus 로고
    • The Association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients
    • Shpichinetsky V, Raz I, Friedlander Y, et al. The Association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients. J Nutr. 2000;130: 2493-2497.
    • (2000) J Nutr. , vol.130 , pp. 2493-2497
    • Shpichinetsky, V.1    Raz, I.2    Friedlander, Y.3
  • 14
    • 36148965526 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy: A meta-analysis
    • Zintzaras E, Uhlig K, Koukoulis GN, Papathanasiou AA, Stefanidis I. Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy: a meta-analysis. J Hum Genet. 2007;52(11):881-890.
    • (2007) J Hum Genet. , vol.52 , Issue.11 , pp. 881-890
    • Zintzaras, E.1    Uhlig, K.2    Koukoulis, G.N.3    Papathanasiou, A.A.4    Stefanidis, I.5
  • 15
    • 84859239810 scopus 로고    scopus 로고
    • Is the C677T polymorphism in methylenetetrahydrofolate reductase gene a risk factor for diabetic nephropathy or diabetes mellitus in a Chinese population
    • Cui WP, Du B, Jia Y, et al. Is the C677T polymorphism in methylenetetrahydrofolate reductase gene a risk factor for diabetic nephropathy or diabetes mellitus in a Chinese population? Arch Med Res. 2012;43(1):42-50.
    • (2012) Arch Med Res , vol.43 , Issue.1 , pp. 42-50
    • Cui, W.P.1    Du, B.2    Jia, Y.3
  • 16
    • 84859227757 scopus 로고    scopus 로고
    • Association of homocysteine, methyleneterahydrofolate reductase gene polymorphism with nephropathy in type 2 diabetes mellitus
    • In Chinese
    • Cao H, Huang DF, Mao L, et al. Association of homocysteine, methyleneterahydrofolate reductase gene polymorphism with nephropathy in type 2 diabetes mellitus. ACTA Universitatis Medicinalis Nanjing (Natural Science). 2005;25:249-251. (In Chinese).
    • (2005) ACTA Universitatis Medicinalis Nanjing (Natural Science). , vol.25 , pp. 249-251
    • Cao, H.1    Huang, D.F.2    Mao, L.3
  • 17
    • 84880314830 scopus 로고    scopus 로고
    • An association study of methylenetetrahydrofolate reductase gene polymorphism with diabetic nephropathy
    • In Chinese
    • Sun JZ, Xu YC, Zhu YL, et al. An association study of methylenetetrahydrofolate reductase gene polymorphism with diabetic nephropathy. J Nephrol Dial Transplant. 2001;10:33-35. (In Chinese).
    • (2001) J Nephrol Dial Transplant. , vol.10 , pp. 33-35
    • Sun, J.Z.1    Xu, Y.C.2    Zhu, Y.L.3
  • 18
    • 2342477858 scopus 로고    scopus 로고
    • Genetic polymorphism of methylenetetrahydrofolate reductase as a risk factor for diabetic nephropathy in Chinese type 2 diabetic patients
    • Sun JZ, Xu YC, Zhu YL, et al. Genetic polymorphism of methylenetetrahydrofolate reductase as a risk factor for diabetic nephropathy in Chinese type 2 diabetic patients. Diabet Res Clin Pract. 2004;64:185-190.
    • (2004) Diabet Res Clin Pract. , vol.64 , pp. 185-190
    • Sun, J.Z.1    Xu, Y.C.2    Zhu, Y.L.3
  • 19
    • 84862191385 scopus 로고    scopus 로고
    • Changes of the plasma homocysteine and its mechanism in type 2 diabetes with microangiopathy
    • In Chinese
    • Guo QY, Lu JM, Qin HG, et al. Changes of the plasma homocysteine and its mechanism in type 2 diabetes with microangiopathy. Chin J Diabet. 2002;10:32-36. (In Chinese).
    • (2002) Chin J Diabet. , vol.10 , pp. 32-36
    • Guo, Q.Y.1    Lu, J.M.2    Qin, H.G.3
  • 22
    • 12744274510 scopus 로고    scopus 로고
    • Heterogeneity testing in meta-analysis of genome searches
    • Zintzaras E, Ioannidis JP. Heterogeneity testing in meta-analysis of genome searches. Genet Epidemiol. 2005;28:123-137.
    • (2005) Genet Epidemiol. , vol.28 , pp. 123-137
    • Zintzaras, E.1    Ioannidis, J.P.2
  • 23
    • 39149139125 scopus 로고    scopus 로고
    • Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches
    • Zintzaras E, Lau J. Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches. J Clin Epidemiol. 2008;61: 634-645.
    • (2008) J Clin Epidemiol. , vol.61 , pp. 634-645
    • Zintzaras, E.1    Lau, J.2
  • 26
    • 0035433811 scopus 로고    scopus 로고
    • The association of methylenetetrahydrofolate reductase gene polymorphism with diabetic nephropathy in type 2 diabetes mellitus in Chinese
    • In Chinese
    • Sun JZ, Xu YC, Zhu YL, et al. The association of methylenetetrahydrofolate reductase gene polymorphism with diabetic nephropathy in type 2 diabetes mellitus in Chinese. Chin J Intern Med. 2001;40:529-532. (In Chinese).
    • (2001) Chin J Intern Med. , vol.40 , pp. 529-532
    • Sun, J.Z.1    Xu, Y.C.2    Zhu, Y.L.3
  • 27
    • 84859249439 scopus 로고    scopus 로고
    • Matched case-control study on the association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and diabetic nephropathy in type 2 diabetic patients
    • In Chinese
    • Lin R, Wang CN, Liu XM. Matched case-control study on the association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and diabetic nephropathy in type 2 diabetic patients. Modern Prevent Med. 2009;36:3801-3804. (In Chinese).
    • (2009) Modern Prevent Med. , vol.36 , pp. 3801-3804
    • Lin, R.1    Wang, C.N.2    Liu, X.M.3
  • 28
    • 84859241741 scopus 로고    scopus 로고
    • Relationship between plasma level of homocysteine and urine microalbumin in incipient type 2 diabetic nephropathy
    • In Chinese
    • Yue H, Liu J, Kang WJ, et al. Relationship between plasma level of homocysteine and urine microalbumin in incipient type 2 diabetic nephropathy. Chin J Gen Pract. 2006;15:725-729. (In Chinese).
    • (2006) Chin J Gen Pract. , vol.15 , pp. 725-729
    • Yue, H.1    Liu, J.2    Kang, W.J.3
  • 29
    • 77957863236 scopus 로고    scopus 로고
    • Study on the relationship between gene polymorphisms of N5,10-methylenetetrahydrofolate reductase and nephropathy in type 2 diabetes mellitus in Gansu Han Chinese of China
    • In Chinese
    • Chen AR, Ning YY, Zhu XZ, et al. Study on the relationship between gene polymorphisms of N5,10-methylenetetrahydrofolate reductase and nephropathy in type 2 diabetes mellitus in Gansu Han Chinese of China. Clin J Prev Contr Chron Non-Commun Dis. 2004;12:195-197. (In Chinese).
    • (2004) Clin J Prev Contr Chron Non-Commun Dis. , vol.12 , pp. 195-197
    • Chen, A.R.1    Ning, Y.Y.2    Zhu, X.Z.3
  • 30
    • 84859240770 scopus 로고    scopus 로고
    • Relationship between methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy in type 2 diabetes mellitus in the Hans of Hebei Province
    • In Chinese
    • Xu JS, Zhang J, Shan BE, et al. Relationship between methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy in type 2 diabetes mellitus in the Hans of Hebei Province. Clin Focus. 2003;18:787-789. (In Chinese).
    • (2003) Clin Focus. , vol.18 , pp. 787-789
    • Xu, J.S.1    Zhang, J.2    Shan, B.E.3
  • 31
    • 0034884601 scopus 로고    scopus 로고
    • Relationship between methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy
    • In Chinese
    • Wang LQ, Wang JY, Xue YM, et al. Relationship between methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy. Chin J Med Genet. 2001;18:226-228. (In Chinese).
    • (2001) Chin J Med Genet. , vol.18 , pp. 226-228
    • Wang, L.Q.1    Wang, J.Y.2    Xue, Y.M.3
  • 32
    • 2442469680 scopus 로고    scopus 로고
    • Study on the relationship between N5, 10-methylenetetrahydrofolate reductase gene polymorphism and the susceptibility to microangiopathy in type 2 diabetes mellitus
    • In Chinese
    • Yang GQ, Lu JM, Pan CY. Study on the relationship between N5, 10-methylenetetrahydrofolate reductase gene polymorphism and the susceptibility to microangiopathy in type 2 diabetes mellitus. Chin J Endocrinol Metab. 2001;17:224-227. (In Chinese).
    • (2001) Chin J Endocrinol Metab. , vol.17 , pp. 224-227
    • Yang, G.Q.1    Lu, J.M.2    Pan, C.Y.3
  • 33
    • 84859250527 scopus 로고    scopus 로고
    • Correlation between single nucleotide polymorphisms in methylenetetrahydrofolate reductase gene and type 2 diabetes mellitus in Chinese Han nationality
    • In Chinese
    • Zhang YD, Shi L, Yu M, et al. Correlation between single nucleotide polymorphisms in methylenetetrahydrofolate reductase gene and type 2 diabetes mellitus in Chinese Han nationality. J Mod Lab Med. 2010;25:14-16. (In Chinese).
    • (2010) J Mod Lab Med. , vol.25 , pp. 14-16
    • Zhang, Y.D.1    Shi, L.2    Yu, M.3
  • 34
    • 84859228199 scopus 로고    scopus 로고
    • Correlation of MTHFR gene polymorphism and plasma homocysteine with microalbuminuria in type 2 diabetes
    • In Chinese
    • Wen J, Chen ZQ, Li XM, et al. Correlation of MTHFR gene polymorphism and plasma homocysteine with microalbuminuria in type 2 diabetes. Shanghai Med J. 2008;31:47-51. (In Chinese).
    • (2008) Shanghai Med J. , vol.31 , pp. 47-51
    • Wen, J.1    Chen, Z.Q.2    Li, X.M.3
  • 35
    • 84859262420 scopus 로고    scopus 로고
    • The association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and type 2 diabetes mellitus
    • In Chinese
    • Chen P, Pan YH, Sun DL, et al. The association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and type 2 diabetes mellitus. J Qiqihar Med Coll. 2008;29: 672-673. (In Chinese).
    • (2008) J Qiqihar Med Coll. , vol.29 , pp. 672-673
    • Chen, P.1    Pan, Y.H.2    Sun, D.L.3
  • 36
    • 79953759095 scopus 로고    scopus 로고
    • Genetic associations in diabetic nephropathy: A meta-analysis
    • Mooyaart AL, Valk EJJ, van Es LA, et al. Genetic associations in diabetic nephropathy: a meta-analysis, Diabetologia. 2011;54: 544-553.
    • (2011) Diabetologia , vol.54 , pp. 544-553
    • Mooyaart, A.L.1    Valk, E.J.J.2    Van Es, L.A.3
  • 37
    • 0029066299 scopus 로고
    • Motulsky AGA quantitative assessment of plasma homocysteine as a risk factor for vascular disease
    • Boushey CJ, Beresford SAA, Omenn GS. Motulsky AGA quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA. 1995;274:1049-1057.
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.A.2    Omenn, G.S.3
  • 38
    • 0031662210 scopus 로고    scopus 로고
    • Kessling AM MTHFR association with arteriosclerotic vascular disease
    • Fletcher O. Kessling AM MTHFR association with arteriosclerotic vascular disease? Hum Genet. 1998;103:11-21.
    • (1998) Hum Genet , vol.103 , pp. 11-21
    • Fletcher, O.1
  • 39
    • 33845200050 scopus 로고    scopus 로고
    • MTHFR C677T and A1298C gene polymorphisms an hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients
    • Mtiraoui N, Ezzidi I, Chaieb M, et al. MTHFR C677T and A1298C gene polymorphisms an hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients. Diabetes Res Clin Pract. 2007;75:99-106.
    • (2007) Diabetes Res Clin Pract. , vol.75 , pp. 99-106
    • Mtiraoui, N.1    Ezzidi, I.2    Chaieb, M.3
  • 40
    • 0042733751 scopus 로고    scopus 로고
    • Homocysteine induces vascular endothelial growth factor expression in differentiated THP-1 macrophages
    • Maeda M, Yamamoto I, Fujio Y, et al. Homocysteine induces vascular endothelial growth factor expression in differentiated THP-1 macrophages. Biochim Biophys Acta. 2003;1623: 41-46.
    • (2003) Biochim Biophys Acta. , vol.1623 , pp. 41-46
    • Maeda, M.1    Yamamoto, I.2    Fujio, Y.3
  • 41
    • 2442572249 scopus 로고    scopus 로고
    • Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4
    • Roybal CN, Yang S, Sun CW, et al. Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4. J Biol Chem. 2004;279:14844-14852.
    • (2004) J Biol Chem. , vol.279 , pp. 14844-14852
    • Roybal, C.N.1    Yang, S.2    Sun, C.W.3
  • 42
    • 33750713086 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice
    • Sung SH, Ziyadeh FN, Wang A, et al. Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice. J Am Soc Nephrol. 2006;117:3093-3104.
    • (2006) J Am Soc Nephrol. , vol.117 , pp. 3093-3104
    • Sung, S.H.1    Ziyadeh, F.N.2    Wang, A.3
  • 43
    • 0032743217 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in IDDM patients
    • Shcherbak NS, Shutskaya ZV, Sheidina AM, et al. Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in IDDM patients. Mol Genet Metab. 1999;68(3):375-378.
    • (1999) Mol Genet Metab. , vol.68 , Issue.3 , pp. 375-378
    • Shcherbak, N.S.1    Shutskaya, Z.V.2    Sheidina, A.M.3
  • 44
    • 0032497143 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in NIDDM patients
    • Neugebauer S, Baba T, Watanabe T. Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in NIDDM patients. Lancet. 1998;352:454-457.
    • (1998) Lancet. , vol.352 , pp. 454-457
    • Neugebauer, S.1    Baba, T.2    Watanabe, T.3
  • 45
    • 0007762495 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphism is not associated to diabetic nephropathy in type 2 diabetes
    • Scaglione L, Ganbino R, Gay M, et al. Methylenetetrahydrofolate reductase gene polymorphism is not associated to diabetic nephropathy in type 2 diabetes. Diabetologia. 1999;42:A329.
    • (1999) Diabetologia. , vol.42
    • Scaglione, L.1    Ganbino, R.2    Gay, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.