Relationship between methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy

Chinese Journal of Medical Genetics

Volumn 18, Issue 4, 2001, Pages 276-278

  Wang, L ^a   Wang, J ^a   Xue, Y ^a   Chen, Y ^a   Zou, H ^a  

^a 187 Central Hospital of Chinese PLA   (China)

Author keywords

Diabetic nephropathy; Homocysteine; Methylenetetrahydrofolate reductase gene; Polymerase chain reaction restriction fragment length polymorphsim

Indexed keywords

MUTAGENESIS; PATIENT MONITORING;

GENE POLYMORPHISM;

GENES;

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALBUMIN;

ADULT; AGED; ARTICLE; CHINESE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DIAGNOSTIC PROCEDURE; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; DIABETIC NEPHROPATHIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HOMOCYSTEINE; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 0034884601     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in NIDDM patients
2. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
3. Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells
4. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
5. Clinical significance of pharmacological modulation of homocysteine metabolism
6. Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus
7. Hyperhomocysteinemia is a risk factor for coronary arteriosclerosis in Japanese patients with type 2 diabetes
8. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase