Influence of phosphodiesterases and cGMP on cAMP generation and on phosphorylation of phospholamban and troponin i by 5-HT4 receptor activation in porcine left atrium

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 8, 2013, Pages 671-684

  Weninger, Sabine ^a   De Maeyer, Joris H ^b   Lefebvre, Romain A ^a  

^a GHENT UNIVERSITY   (Belgium)

^b Movetis NV   (Belgium)

Author keywords

5 HT4 receptor; cAMP; cGMP; Phosphodiesterases; Pig atrium

Indexed keywords

CILOSTAMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP; GUANYLATE CYCLASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IV; PHOSPHOLAMBAN; PRUCALOPRIDE; ROLIPRAM; SEROTONIN 4 RECEPTOR; TROPONIN I; BENZOFURAN DERIVATIVE; CALCIUM BINDING PROTEIN; CYCLIC AMP; ISOBUTYLMETHYLXANTHINE; PHOSPHODIESTERASE INHIBITOR; SEROTONIN; SEROTONIN 4 AGONIST;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HEART LEFT ATRIUM; HEART MUSCLE CONTRACTILE FORCE; INOTROPISM; NONHUMAN; PROTEIN PHOSPHORYLATION; TREATMENT RESPONSE; ANIMAL; HEART ATRIUM; HEART ATRIUM FUNCTION; HEART CONTRACTION; IN VITRO STUDY; MALE; PHOSPHORYLATION; PHYSIOLOGY; SWINE;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; ATRIAL FUNCTION; BENZOFURANS; CALCIUM-BINDING PROTEINS; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; HEART ATRIA; IN VITRO TECHNIQUES; MALE; MYOCARDIAL CONTRACTION; PHOSPHODIESTERASE INHIBITORS; PHOSPHORYLATION; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN; SEROTONIN 5-HT4 RECEPTOR AGONISTS; SWINE; TROPONIN I;

EID: 84880291989     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0855-2     Document Type: Article

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