Study of the regulation of the inotropic response to 5-HT 4 receptor activation via phosphodiesterases and its cross-talk with C-type natriuretic peptide in porcine left atrium

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 385, Issue 6, 2012, Pages 565-577

  Weninger, S ^a   De Maeyer, J H ^b   Lefebvre, R A ^a  

^a GHENT UNIVERSITY   (Belgium)

^b Movetis NV   (Belgium)

Author keywords

5 HT 4 receptor; CAMP cGMP signalling; PDE; Porcine atrium; Prucalopride; Serotonin

Indexed keywords

CILOSTAMIDE; CYCLIC AMP; CYCLIC GMP; ISOBUTYLMETHYLXANTHINE; NATRIURETIC PEPTIDE TYPE C; PHOSPHODIESTERASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IV; PRUCALOPRIDE; ROLIPRAM; SEROTONIN 4 RECEPTOR; ZAPRINAST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; EXPERIMENTAL PIG; HEART LEFT ATRIUM; IN VITRO STUDY; INOTROPISM; MALE; MUSCLE CONTRACTION; NONHUMAN; SIGNAL TRANSDUCTION;

ANIMALS; ATRIAL FUNCTION; BENZOFURANS; CYCLIC AMP; CYCLIC GMP; GUANYLATE CYCLASE; HEART ATRIA; ISOMETRIC CONTRACTION; MALE; NATRIURETIC PEPTIDE, C-TYPE; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN; SEROTONIN 5-HT4 RECEPTOR AGONISTS; SWINE;

EID: 84862880151     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-012-0746-y     Document Type: Article

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