Inhibition of β- but not α1-mediated adrenergic responses in isolated hearts and cardiomyocytes by nitric oxide and 8-bromo cyclic GMP

Cardiovascular Research

Volumn 32, Issue 3, 1996, Pages 622-629

  Ebihara, Yoshinori ^a   Karmazyn, Morris ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Contractile function; Intracellular calcium; Isoproterenol; Nitric oxide; Phenylephrine; Rat, heart; Rat, ventricular myocytes

Indexed keywords

8 BROMO CYCLIC GMP; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; PROPRANOLOL;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; HEART MUSCLE CONTRACTILITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CALCIUM; CELL SIZE; CELLS, CULTURED; CYCLIC GMP; ISOPROTERENOL; MALE; MOLSIDOMINE; MYOCARDIAL CONTRACTION; MYOCARDIUM; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PENICILLAMINE; PERFUSION; PHENYLEPHRINE; PROPRANOLOL; RATS; RATS, SPRAGUE-DAWLEY; S-NITROSO-N-ACETYLPENICILLAMINE; STIMULATION, CHEMICAL; VASODILATOR AGENTS;

EID: 0030245573     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/0008-6363(96)00117-4     Document Type: Article

References (27)

1. [1] Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-526.
2. [2] Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G, 1987. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 84:9265-9269.
3. [3] Gross SS, Wolin MS. Nitric oxide: pathophysiological mechanisms. Annu Rev Physiol 1995;57:737-769.
4. [4] Weyrich AS, Ma X-I, Buerke M, et al. Physiological concentrations of nitric oxide do not elicit an acute negative inotropic effect in unstimulated cardiac muscle. Circ Res 1994;75:692-700.
5. [5] Shen W, Xu X, Ochoa M, Zhao G, Wolin MS, Hintze TH. Role of nitric oxide in the regulation of oxygen consumption in conscious dogs. Circ Res 1994;75:1086-1095.
6. 1 and cell contraction in cultured chick ventricular myocytes. Circ Res 1994;75:285-295.
7. [7] Brady AJB, Poole-Wilson PA, Harding SE. Warren JB. Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am J Physiol 1992;263:H1963-H1966.
8. 2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterase through guanylyl cyclase activation. J Biol Chem 1993;268:26286-26295.
9. [9] Wahler GM, Dollinger SJ. Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase. Am J Physiol 1995;268:C45-C54.
10. [10] Grocott-Mason R, Fort S, Lewis MJ, Shah AM, 1994. Myocardial relaxant effect of exogenous nitric oxide in isolated ejecting hearts. Am J Physiol 1994;266:H1699-H1705.
11. [11] Grocott-Mason R, Anning P, Evans H, Lewis MJ, Shah AM. Modulation of left ventricular relaxation in isolated ejecting heart by endogenous nitric oxide. Am J Physiol 1994;267:H1804-H1813.
12. [12] Brady AJB, Warren JB, Poole-Wilson PA, Williams TJ, Harding SE. Nitrit oxide attenuates cardiac myocyte contraction. Am J Physiol 1993;265:H176-H182.
13. [13] Han X, Shimoni Y, Giles WR. An obligatory role for nitric oxide in autonomic control of mammalian heart rate. J Physiol 1994;476:309-314.
14. [14] Han X, Shimoni Y, Giles WR. A cellular mechanism for nitric-oxide-mediated cholinergic control of mammalian heart rate. J Gen Physiol 1995;106:45-65.
15. [15] Ebihara Y, Haist JV, Karmazyn M. Modulation of endothelin-1 effects on rat hearts and cardiomyocytes by nitric oxide and 8-bromo cyclic GMP. J Mol Cell Cardiol 1996;28:265-277.
16. [16] Balligand J-L, Kelly RA, Marsden PA, Smith TW, Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci USA 1993;90:347-351.
17. [17] Balligand J-C, Ungureanu-Longrois D, Simmons WW, et al. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. J Biol Chem 1994;269:27580-27588.
18. 1-adrenoceptors: an overview. Pharmacol Rev 1993;45:147-175.
19. [19] Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 1994;368:850-853.
20. 2+ mediated through α- and β-adrenoceptors. Circ Res 1988;62:247-265.
21. 2+ transient and contractions in single rat cardiomyocytes. J Mol Cell Cardiol 1992;24:809-820.
22. + exchanger. Circ Res 1991;68:269-279.
23. [23] Clerk A, Bogoyevitch MA, Andersson MB, Sugden PH. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J Biol Chem 1994;269:32848-32857.
24. [24] Dudek RR, Wildhirt S, Conforto A, et al. Inducible nitric oxide synthase activity in myocardium after myocardial infarction in rabbit. Biochem Biophys Res Commun 1994;205:1671-1680.
25. [25] Node K, Kitakaze M, Kosaka H, et al. Plasma nitric oxide end products are increased in the ischemic canine heart. Biochem Biophys Res Commun 1995;211:370-374.
26. [26] Winlaw DS, Smythe GA, Keogh AM, Schyvens CG, Spratt PM, Macdonald PS. Increased nitric oxide production in heart failure. Lancet 1994;344:373-374.
27. [27] O'Murchu B, Miller VM, Perrella MA, Burnett Jr JC. Increased production of nitric oxide in coronary arteries during congestive heart failure. J Clin Invest 1994;93:165-171.