CD44 immunoreactivity in the developing human kidney: A marker of renal progenitor stem cells?

Renal Failure

Volumn 35, Issue 7, 2013, Pages 967-970

  Fanni, Daniela ^a   Fanos, Vassilios ^a   Gerosa, Clara ^a   Senes, Giancarlo ^a   Sanna, Alice ^a   Van Eyken, Peter ^b   Iacovidou, Nicoletta ^c   Monga, Guido ^d   Faa, Gavino ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

CD44; Fetus; Immunohistochemistry; Kidney; Mesenchymal cells; MET; Nephrogenesis

Indexed keywords

HERMES ANTIGEN;

ARTICLE; CAPSULAR CELL; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CORTICAL INTERSTITIAL CELL; FEMALE; FETUS; GESTATIONAL AGE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTRAGLOMERULAR CELL; KIDNEY CELL; KIDNEY DEVELOPMENT; KIDNEY INTERSTITIUM; MALE; MEDULLARY INTERSTITIAL CELL; MESENCHYME; MESENCHYME CELL; NERVE CELL; NEWBORN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL STEM CELL; STEM CELL;

ANTIGENS, CD44; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL TRANSDIFFERENTIATION; FEMALE; FETUS; GESTATIONAL AGE; HUMANS; HYALURONIC ACID; IMMUNOHISTOCHEMISTRY; INFANT, NEWBORN; KIDNEY; MALE; ORGANOGENESIS; PODOCYTES; STEM CELLS;

EID: 84880286319     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2013.808955     Document Type: Article

References (19)

1. Isacke CM, Yarwood H. The hyaluronan receptor, CD44. Int J Biochem Cell Biol. 2002;34(7):718-721.
2. Culty M, Nguyen HA, Underhill CB. The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan. J Cell Biol. 1992;116(4):1055-1062.
3. Pure E, Cuff CA. A crucial role for CD44 in inflammation. Trends Mol Med. 2001;7(5):213-221.
4. Schmits R, Filmus J, Gerwin N, et al. CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity. Blood. 1997;90(6):2217-2233.
5. van der Windt GJ, Hoogendijk AJ, de Vos AF, et al. The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia. Lab Investig J Tech Methods Pathol. 2011;91(4):588-597.
6. Fatima H, Moeller M, Smeets B, et al. Parietal epithelial cell activation distinguishes early recurrence of FSGS in the transplant from minimal change disease. Modern Pathol. 2011;24(Suppl 1): 344A.
7. Faa G, Gerosa C, Fanni D, et al. Morphogenesis and molecular mechanisms involved in human kidney development. J Cell Physiol. 2012;227(3):1257-1268.
8. Fanos V, Mussap M, Cuzzolin L, et al. Renal safety of antifungals and non-steroidal anti-inflammatory drugs in the newborn. In: Fanos V, Chevalier RL, Faa G, Cataldi L, eds. Developmental nephrology: from embryology to metabolomics. Quartu Sant'Elena: Hygeia Press; 2011:131-148
9. Anglani F, Forino M, Del Prete D, et al. In search of adult renal stem cells. J Cell Mol Med. 2004;8(4):474-487.
10. Bussolati B, Bruno S, Grange C, et al. Isolation of renal progenitor cells from adult human kidney. Am J Pathol. 2005;166(2):545-555.
11. Fatima H, Moeller MJ, Smeets B, et al. Parietal epithelial cell activation marker in early recurrence of FSGS in the transplant. CJASN. 2012;7(11):1852-1858.
12. Appel D, Kershaw DB, Smeets B, et al. Recruitment of podocytes from glomerular parietal epithelial cells. JASN. 2009; 20(2):333-343.
13. Sagrinati C, Netti GS, Mazzinghi B, et al. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. JASN. 2006;17(9):2443-2456.
14. Swetha G, Chandra V, Phadnis S, Bhonde R. Glomerular parietal epithelial cells of adult murine kidney undergo EMT to generate cells with traits of renal progenitors. J Cell Mol Med. 2011; 15(2):396-413.
15. Humphreys BD, Valerius MT, Kobayashi A, et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008;2(3):284-291.
16. Ng YY, Fan JM, Mu W, et al. Glomerular epithelial-myofibroblast transdifferentiation in the evolution of glomerular crescent formation. Nephrol Dial Transplant. 1999;14(12):2860-2872.
17. Anglani F, Ceol M, Mezzabotta F, et al. The renal stem cell system in kidney repair and regeneration. J Virtual Library. 2008;13: 6395-6405.
18. Faa G, Gerosa C, Fanni D, et al. Kidney embryogenesis: how to look at old things with new eyes. In: Fanos V, Chevalier RL, Faa G, Cataldi L, ed. Developmental nephrology: from embryology to metabolomics. Quartu Sant'Elena: Hygeia Press; 2011:23-45
19. Fanni D, Gerosa C, Nemolato S, et al. "Physiological" renal regenerating medicine in VLBW preterm infants: could a dream come true? J Maternal-fetal Neonatal Med. 2012;25(Suppl 3):41-48.